Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: An apparatus and method for generating a low concentration of gas within a carrier gas flow employing one or more miniature one-piece cylinders filled under pressure with a pure gas, or a concentrated gas balanced with an inert gas or gas mixture. Released from the cylinder through a pierced or other controlled opening, the flow of the gas is regulated by a pressure regulator and a micro orifice to be blended into a steady stream of diluent gas, typically ambient air, to form a desired gas concentration. No gas is generated if the pressure of the gas in the cylinder, which is monitored constantly by a pressure transducer, is below a predetermined level. The apparatus can be built into a portable device, or an automated docking station (or calibration station) for testing and calibrating gas detection and monitoring instruments, or into a fixed gas detection system for performing such functions.

Abstract: A gas detection instrument comprises a combustible gas sensor and associated circuitry, which supplies power to the sensor and measures and displays resulting sensor response. The supplied power is switched between timed pulses of electricity and steady state electricity, with the intermittent electricity being employed only when no significant change in sensor output has been detected. Alternatively, timed pulses of electricity are maintained, and predictive software algorithms are used to give readings for gas concentration during interruption of the power supply. The sensor operation enables the instrument to respond to rapid changes in gas concentration while minimizing power consumption of the sensor.

Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: A gas detection instrument comprises a combustible gas sensor and associated circuitry, which supplies power to the sensor and measures and displays resulting sensor response. The supplied power is switched between timed pulses of electricity and steady state electricity, with the intermittent electricity being employed only when no significant change in sensor output has been detected. Alternatively, timed pulses of electricity are maintained, and predictive software algorithms are used to give readings for gas concentration during interruption of the power supply. The sensor operation enables the instrument to respond to rapid changes in gas concentration while minimizing power consumption of the sensor.

Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: The invention provides sodium channel modulating compounds which are useful for treating diseases or conditions associated with sodium channel activity, such as neuropathic pain. The invention also provides pharmaceutical compositions comprising a compound of the present invention, as well as therapeutic methods comprising administering such a compound or salt to a mammal (e.g. a human).

Abstract: The compounds of this invention comprise 2-10 ligands covalently connected, each of the ligands being capable of binding to a ligand binding site in a Na+ channel, thereby modulating the biological activities thereof.

Abstract: A board handling apparatus for receiving, collecting, and stacking boards cut to length by a sawing device includes a frame, a plurality of take-away conveyors adjustably secured to the frame for receiving and collecting the boards, a scissor lift mechanism secured generally under the take-away conveyors for lifting a platform, and a pair of extendable fingers operably supported on the platform for raising/extending/lowering/retracting movement for stacking the collected boards on a pallet. The take-away conveyors are adjustably secured to the frame so that their spacing can be adjusted to an optimal spacing. Also, additional take-away conveyors can be added if desired. The fingers are adjustably secured on the platform so that their spacing can be adjusted to an optimal spacing. Additional fingers can be attached to the platform if desired. Also, additional lift mechanisms can be added with additional platforms to expand the capability of the board handling apparatus.

Abstract: A method and apparatus for synchronizing a received television signal to a subcarrier locked signal is provided. The apparatus includes a comparison block for determining whether the received television signal and subcarrier locked signal are related by a predetermined fixed frequency relationship and for providing indications of the same, and a signal generation block for dividing down the subcarrier locked signal according to the predetermined fixed frequency relationship so as to provide an output signal which is synchronized with the subcarrier locked signal, and at a frequency determined according to the fixed frequency relationship when the signals are related. The apparatus is particularly useful in PIP applications where the received television signal is a horizontal signal and the subcarrier locked signal is a four times multiple of the subcarrier frequency.

Abstract: Apparatus and methods for remodulating digital luminance and color difference components for display as PIP information, or together with other composite video components for multi-PIP and test pattern applications are disclosed. A digital encoder is used for conducting a digital quadrature modulation on the color difference components and for digitally adding the luminance signal thereto prior to the converting of the remodulated information into an analog format. Preferably, the digital video information output by the encoder is in the form Y1+(R-Y)1, Y1 +(B-Y)1, Y2-(R-Y)1, Y2-(B-Y)1, Y3+(R-Y)2. Y3+(b-Y)2, Y4 -(R-Y)2, . . . , where Y is the luminance component, R-Y and B-Y are color difference components, and where the numbers index received samples of the video components with the luminance component being sampled at twice the frequency of the color difference components.

Abstract: A stabilized gated oscillator that provides pulses at a predetermined repetition rate in phase coherence with a gating signal includes a ceramic resonator in a feedback resonant circuit between the output terminal and the input terminal of a linear amplifier. The resonant circuit, which establishes the repetition rate, is constructed to provide an oscillator frequency in a frequency range between two resonant frequencies of the ceramic resonator wherein the ceramic resonator acts as an inductance.

Abstract: A gated oscillator circuit for generating a sampling signal for digitally processing television signals, uses an LC oscillator to achieve, high frequency stability and reduced edge jitter. Circuitry is provided on both sides of a tank circuit in the oscillator for decoupling the tank circuit from other active circuit elements thereby enhancing the frequency stability.