Patents by Inventor David C. Greenspan

David C. Greenspan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20010041186
    Abstract: A method for treating wounds including contacting a wound with an effective wound healing amount of bioactive glass and topical antibiotic and composition for the accelerated healing of wounds and burns including particulates of bioactive glass and at least one topical antibiotic.
    Type: Application
    Filed: October 1, 1998
    Publication date: November 15, 2001
    Inventors: DAVID C. GREENSPAN, JON K. WEST
  • Patent number: 6244871
    Abstract: A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel, etc. having a particle size range <90 &mgr;m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
    Type: Grant
    Filed: January 7, 2000
    Date of Patent: June 12, 2001
    Assignee: Univ. of Maryland Baltimore
    Inventors: Leonard J. Litkowski, Gary D. Hack, David C. Greenspan
  • Patent number: 6197342
    Abstract: This invention relates to a synthetic bone replacement material impregnated with drugs such as antibiotics and growth hormones, which facilitate and promote the regeneration of bone and/or soft tissue. Methods for making the impregnated material and its medical use are also taught.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: March 6, 2001
    Inventors: Paul D. Thut, Leonard J. Litkowski, David C. Greenspan
  • Patent number: 6171986
    Abstract: A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the -near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: January 9, 2001
    Assignee: USBiomaterials Corp.
    Inventors: Jipin Zhong, David C. Greenspan
  • Patent number: 6153221
    Abstract: This invention relates to a synthetic bone replacement material impregnated with drugs such as antibiotics and growth hormones, which facilitate and promote the regeneration of bone and/or soft tissue. Methods for making the impregnated material and its medical use are also taught.
    Type: Grant
    Filed: September 21, 1998
    Date of Patent: November 28, 2000
    Assignees: Paul D. Thut, Leonard J. Litkowski
    Inventors: Paul D. Thut, Leonard J. Litkowski, David C. Greenspan
  • Patent number: 6086374
    Abstract: A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel, etc. having a particle size range <90 .mu.gm which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity and tooth surface remineralization.
    Type: Grant
    Filed: January 29, 1997
    Date of Patent: July 11, 2000
    Assignee: USBiomaterials Corp.
    Inventors: Leonard J. Litkowski, Gary D. Hack, David C. Greenspan
  • Patent number: 6010713
    Abstract: A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.
    Type: Grant
    Filed: January 13, 1998
    Date of Patent: January 4, 2000
    Assignee: USBiomaterials Corp.
    Inventors: Jipin Zhong, David C. Greenspan
  • Patent number: 5977204
    Abstract: Biodegradable polymeric therapeutic implant materials incorporating bioactive ceramics such as Bioglass.RTM. ceramic are provided. These implants provide increased mechanical properties and pH control, enabling the use of these materials to design porous and nonporous therapeutic implants used as cell scaffolds for healing of tissue defects or fixation devices, having desired degradation times, mechanical properties, elasticity and biocompatibility.
    Type: Grant
    Filed: April 11, 1997
    Date of Patent: November 2, 1999
    Assignees: OsteoBiologics, Inc., USBiomaterials Corporation
    Inventors: Barbara D. Boyan, Gabriele Niederauer, Kristine Kieswetter, Neil C. Leatherbury, David C. Greenspan
  • Patent number: 5972384
    Abstract: This invention relates to a synthetic bone replacement material impregnated with drugs such as antibiotics and growth hormones, which facilitate and promote the regeneration of bone and/or soft tissue. Methods for making the impregnated material and its medical use are also taught.
    Type: Grant
    Filed: October 1, 1997
    Date of Patent: October 26, 1999
    Assignees: University of Maryland, Baltimore, USBiomaterials, Corp.
    Inventors: Paul D. Thut, Leonard J. Litkowski, David C. Greenspan
  • Patent number: 5874101
    Abstract: A process for making bioactive glasses is described including preparing a reaction mixture of reactants capable of forming a sol-gel, aging the reaction mixture, near equilibrium drying a gel resulting from the reaction mixture, and heating the -near equilibrium-dried gel described. Also described are near equilibrium-dried bioactive glass compositions.
    Type: Grant
    Filed: April 14, 1997
    Date of Patent: February 23, 1999
    Assignee: USBiomaterials Corp.
    Inventors: Jipin Zhong, David C. Greenspan
  • Patent number: 5834008
    Abstract: A method for treating wounds including contacting a wound with an effective wound healing amount of bioactive glass and topical antibiotic and composition for the accelerated healing of wounds and burns including particulates of bioactive glass and at least one topical antibiotic.
    Type: Grant
    Filed: September 19, 1996
    Date of Patent: November 10, 1998
    Assignee: U.S. Biomaterials Corp.
    Inventors: David C. Greenspan, Jon K. West
  • Patent number: 5735942
    Abstract: A novel silica based bioactive glass composition that can be used in conjunction with a delivery agent such as a toothpaste, gel saliva, etc. having a particle size range <90 .mu.m which will form a rapid and continuous reaction with body fluids due to the immediate and long term ionic release of Ca and P from the core silica particles, to produce a stable crystalline hydroxy carbonate apatite layer deposited onto and into the dentin tubules for the immediate and long term reduction of dentin hypersensitivity.
    Type: Grant
    Filed: July 16, 1997
    Date of Patent: April 7, 1998
    Assignees: USBiomaterials Corporation, University of Maryland
    Inventors: Leonard J. Litkowski, Gary D. Hack, David C. Greenspan
  • Patent number: 4977001
    Abstract: A cladding for a molybdenum body such as a molybdenum tube for protecting the molybdenum from corrosive high temperature environments. The cladding contains oxides of molybdenum, aluminum, silicon and alkali metals in about the following percentages by weight of the total metal content: molybdenum 18-40 percent; aluminum 10-25 percent; silicon 25-50 percent; and, alkali metals 8-12 percent. The cladding may be formed by bringing the molybdenum body into contact in the presence of oxygen, with a refractory containing oxides of aluminum, silicon and alkali metals at a temperature greater than 400.degree. C.
    Type: Grant
    Filed: January 20, 1988
    Date of Patent: December 11, 1990
    Assignee: Vesuvius Crucible Company
    Inventor: David C. Greenspan
  • Patent number: 4749416
    Abstract: Temperature sensing apparatus for use in the sidewall or bottom of a vessel for containing molten metal. A temperature sensing element is mounted within a sheath which is provided with a sacrificial coating to protect the sheath from premature oxidation such as may occur during a gas-flame pre-heat cycle. The sheath which is being protected against premature oxidation by the sacrificial coating is a composite of a closed end metal tube and a plurality of porous cermet layers of aluminum oxide-chromium oxide-molybdenum with the concentration of molybdenum decreasing in proceeding from the inner cermet layer to the outer cermet layer. The outer cermet layer of the sheath is covered by a ceramic layer of aluminum oxide. The sacrificial coating consists of a layer of zirconium oxide in combination with and covered by a layer of fibrous alumina. The sacrificial coating is typically destroyed by the end of a pre-heat cycle.
    Type: Grant
    Filed: August 1, 1986
    Date of Patent: June 7, 1988
    Assignee: System Planning Corporation
    Inventor: David C. Greenspan
  • Patent number: 4746534
    Abstract: A protective sheath for a temperature sensing device for use in determining the temperature of molten metals. The temperature sensing device, such as a thermocouple, is encased in a molybdenum tube which is coated with successive porous layers of molybdenum, a plurality of layers of Al.sub.2 O.sub.3 -Cr.sub.2 O.sub.3 -Mo in a decreasing concentration of Mo in proceeding from the inner to the outer layers, and a layer of substantially pure Al.sub.2 O.sub.3 -Cr.sub.2 O.sub.3. The Al.sub.2 O.sub.3 -Cr.sub.2 O.sub.3 layer may be covered with an outer coating of a material, such as boron nitride, to protect the Al.sub.2 O.sub.3 -Cr.sub.2 O.sub.3 layer from attack by slag. Alternating layers of Al.sub.2 O.sub.3 -Cr.sub.2 O.sub.3 and boron nitride may be applied as outermost sacrificial layers.
    Type: Grant
    Filed: November 10, 1987
    Date of Patent: May 24, 1988
    Assignee: System Planning Corporation
    Inventors: R. Michael Phillippi, David C. Greenspan, Richard T. Ellis, Tadeusz M. Drzewiecki, Taki Negas, Ernie Tokay, James R. Bush
  • Patent number: 4721534
    Abstract: A protective sheath for a temperature sensing device for use in determining the temperature of molten metals. The temperature sensing device, such as a thermocouple, is encased in a molybdenum tube which is coated with successive porous layers of molybdenum, a plurality of layers of Al.sub.2 O.sub.3 --Cr.sub.2 O.sub.3 --Mo in a decreasing concentration of Mo in proceeding from the inner to the outer layers, and a layer of substantially pure Al.sub.2 O.sub.3 --Cr.sub.2 O.sub.3. The Al.sub.2 O.sub.3 --Cr.sub.2 O.sub.3 layer may be covered with an outer coating of a material, such as boron nitride, to protect the Al.sub.2 O.sub.3 --Cr.sub.2 O.sub.3 layer from attack by slag. Alternating layers of Al.sub.2 O.sub.3 --Cr.sub.2 O.sub.3 and boron nitride may be applied as outermost sacrificial layers.
    Type: Grant
    Filed: September 12, 1985
    Date of Patent: January 26, 1988
    Assignee: System Planning Corporation
    Inventors: R. Michael Phillippi, David C. Greenspan, Richard T. Ellis, Tadeusz M. Drzewiecki, Taki Negas, Ernie Tokay, James R. Bush
  • Patent number: 4721533
    Abstract: An immersion pyrometer having an outer casing comprising a mixture of graphite and a refractory metal oxide for contact with molten metal, an inner sheath enclosed by said outer casing, said inner sheath comprising a closed end metal tube wherein the closed end is in heat transfer contact with said outer casing, and a thermocouple within said inner sheath.
    Type: Grant
    Filed: August 1, 1986
    Date of Patent: January 26, 1988
    Assignee: System Planning Corporation
    Inventors: R. Michael Phillippi, David C. Greenspan, Ernie Tokay