Patents by Inventor David C. Humber

David C. Humber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of cephalosporin compounds
    Patent number: 4258183
    Abstract: A process for the preparation of a 3-carbamoyloxymethyl cephalosporin compound which comprises hydrolyzing a 3-phosphonocarbamoyloxymethyl cephalosporin compound. The hydrolysis is preferably effected at a pH in the range of pH3 to 4, for example using aqueous sodium hydrogen carbonate.
    Type: Grant
    Filed: September 20, 1979
    Date of Patent: March 24, 1981
    Assignee: Glaxo Group Limited
    Inventors: David C. Humber, Stuart B. Laing, Gordon G. Weingarten
  • 7.beta.-[2-Aryl-2-(etherified oximino)acetamido]-3-N-substituted carbamoyloxymethylceph-3-em-4-carboxylic acids
    Patent number: 4122259
    Abstract: Cephalosporin antibiotics in which the 7.beta.-acylamido group is syn 2-aryl-2-(etherified imino) acetamido and in which the 3-position substituent is an alkyl-, alkenyl-etc. substituted carbamoyloxymethyl group exhibit high antibacterial activity against a broad range of gram positive and gram negative organisms, particularly high stability to .beta.-lactamases produced by various organisms, and stability in vivo. The compounds are syn isomers or exist as mixtures of syn and anti isomers containing at least 90% of the syn isomer.
    Type: Grant
    Filed: December 10, 1976
    Date of Patent: October 24, 1978
    Assignee: Glaxo Laboratories Limited
    Inventor: David C. Humber