Patents by Inventor David C. Kravitz
David C. Kravitz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11942209Abstract: Methods, systems, and apparatus monitor medication usage data for one patient or a population of patients, which can be processed to determine compliance patterns. Such methods and systems can associate, analyze, organize and present medication usage data, compliance patterns, and correlations between compliance patterns and outcomes data for electronic analysis or analysis by a caretaker. Such methods, systems, and apparatus permit analysis of compliance patterns to enable, for example, establishment or adjustment of safe and effective treatment regimens, and may include feedback systems for ensuring authenticity of medication and/or effects of medication on a patient.Type: GrantFiled: October 22, 2018Date of Patent: March 26, 2024Assignee: I.D. THERAPEUTICS LLCInventors: Steven L. Mayer, David C. Kravitz, Tracey H. Mayer
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Patent number: 10572627Abstract: Methods and apparatus monitor medication usage data for one patient or a population of patients, which can be processed to determine compliance patterns. Such methods and systems can associate, analyze, organize and present medication usage data, compliance patterns, and correlations between compliance patterns and outcomes data for electronic analysis or analysis by a caretaker. Such methods and apparatus permit analysis of compliance patterns to enable, for example, establishment or adjustment of safe and effective treatment regimens, and may include feedback systems for ensuring authenticity of medication and/or effects of medication on a patient. Such methods and apparatus also permit detection of medication in a biological sample of the patient through a medication monitor having a detection device, such as a skin-prick device, and a glucose sensor that can detect a target agent in the biological sample.Type: GrantFiled: February 17, 2016Date of Patent: February 25, 2020Assignee: I.D. THERAPEUTICS LLCInventors: Steven L. Mayer, David C. Kravitz, Tracey H. Mayer
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Patent number: 10420337Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue with a perfusate; and a sensor operatively connected to the perfusion circuit. The sensor includes a solid support to which is attached a recognition molecule that permits detection of the target agent. The recognition molecule specifically binds to the target agent in the presence of the target agent but not significantly to other agents. The sensor also includes an enzyme that can catalyze the conversion of a substance to glucose. In the presence of the target agent the enzyme can convert the substance into glucose, which can then be detected and optionally measured by the sensor.Type: GrantFiled: March 15, 2013Date of Patent: September 24, 2019Assignee: LIFELINE SCIENTIFIC, INC.Inventors: Steven L. Mayer, David C. Kravitz, Tracey H. Mayer
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Patent number: 10258032Abstract: A bag includes an organ transporter compartment to contain an organ transporter disposed in the transporter compartment. The bag may include openings to access portions of the organ transporter, such as a battery or power cable, when the organ transporter is disposed in the bag. The bag may also include a frame and handles. The handles may include structure adapted to mate with handles on the organ transporter. The bag may also include a single cover that provides access to multiple compartments with their own internal covers. Also, the bag may include windows to view documents stored in the bag and/or to view and/or display control panels on the organ transporter.Type: GrantFiled: January 11, 2012Date of Patent: April 16, 2019Assignee: LIFELINE SCIENTIFIC, INC.Inventors: David C. Kravitz, Peter DeMuylder, Brian Otts, Stephan Merkle, Jeremiah P. O'Leary, Christopher E. Svensrud
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Publication number: 20190057765Abstract: Methods, systems, and apparatus monitor medication usage data for one patient or a population of patients, which can be processed to determine compliance patterns. Such methods and systems can associate, analyze, organize and present medication usage data, compliance patterns, and correlations between compliance patterns and outcomes data for electronic analysis or analysis by a caretaker. Such methods, systems, and apparatus permit analysis of compliance patterns to enable, for example, establishment or adjustment of safe and effective treatment regimens, and may include feedback systems for ensuring authenticity of medication and/or effects of medication on a patient.Type: ApplicationFiled: October 22, 2018Publication date: February 21, 2019Applicant: I.D. THERAPEUTICS LLCInventors: Steven L. MAYER, David C. KRAVITZ, Tracey H. MAYER
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Publication number: 20160162659Abstract: Methods and apparatus monitor medication usage data for one patient or a population of patients, which can be processed to determine compliance patterns. Such methods and systems can associate, analyze, organize and present medication usage data, compliance patterns, and correlations between compliance patterns and outcomes data for electronic analysis or analysis by a caretaker. Such methods and apparatus permit analysis of compliance patterns to enable, for example, establishment or adjustment of safe and effective treatment regimens, and may include feedback systems for ensuring authenticity of medication and/or effects of medication on a patient. Such methods and apparatus also permit detection of medication in a biological sample of the patient through a medication monitor having a detection device, such as a skin-prick device, and a glucose sensor that can detect a target agent in the biological sample.Type: ApplicationFiled: February 17, 2016Publication date: June 9, 2016Applicant: I.D. THERAPEUTICS LLCInventors: Steven L. MAYER, David C. KRAVITZ, Tracey H. MAYER
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Publication number: 20160042084Abstract: Methods of monitoring, maintaining, and/or restoring viability of at least one organ in a perfusion apparatus are disclosed. The methods include monitoring data comprising information relating to events occurring while at least one organ is present in a perfusion apparatus to form a data record. And they further include connecting the perfusion apparatus to a network through wiring or wirelessly, and continuously uploading the data record to a database at a location away from the perfusion apparatus in such a manner that a database computer that obtains the data record from the database can at least one of manage, track, monitor, and diagnose the at least one organ in the perfusion apparatus in real-time based upon the information in the data record.Type: ApplicationFiled: October 21, 2015Publication date: February 11, 2016Inventors: Donald R. OWEN, David C. KRAVITZ, John BRASSIL, Kelvin G.M. BROCKBANK, Andrew BURROUGHS, Douglas SCHEIN, Stanley HARRIS, Dennis J. STEIBEL, Richard FRASER, Christopher G. CURTIS
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Patent number: 8962303Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. In perfusion, organ perfusion pressure is preferably controlled in response to a sensor disposed in an end of tubing placed in the organ, by a pneumatically pressurized medical fluid reservoir, providing perfusion pressure fine tuning, overpressurization prevention and emergency flow cut-off. In the hypothermic mode, the organ is perfused with a medical fluid, preferably a simple crystalloid solution containing antioxidants, intermittently or in slow continuous flow. The medical fluid may be fed into the organ from an intermediary tank having a low pressure head to avoid organ overpressurization. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate.Type: GrantFiled: August 10, 2011Date of Patent: February 24, 2015Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Douglas Schein
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Publication number: 20140272923Abstract: An apparatus for perfusing an organ or tissue includes a perfusion circuit for perfusing the organ or tissue with a perfusate; and a sensor operatively connected to the perfusion circuit. The sensor includes a solid support to which is attached a recognition molecule that permits detection of the target agent. The recognition molecule specifically binds to the target agent in the presence of the target agent but not significantly to other agents. The sensor also includes an enzyme that can catalyze the conversion of a substance to glucose. In the presence of the target agent the enzyme can convert the substance into glucose, which can then be detected and optionally measured by the sensor.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Applicant: LIFELINE SCIENTIFIC, INC.Inventors: Steven L. MAYER, David C. KRAVITZ, Tracey H. MAYER
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Publication number: 20140278468Abstract: Methods and apparatus monitor medication usage data for one patient or a population of patients, which can be processed to determine compliance patterns. Such methods and systems can associate, analyze, organize and present medication usage data, compliance patterns, and correlations between compliance patterns and outcomes data for electronic analysis or analysis by a caretaker. Such methods and apparatus permit analysis of compliance patterns to enable, for example, establishment or adjustment of safe and effective treatment regimens, and may include feedback systems for ensuring authenticity of medication and/or effects of medication on a patient. Such methods and apparatus also permit detection of medication in a biological sample of the patient through a medication monitor having a detection device, such as a skin-prick device, and a glucose sensor that can detect a target agent in the biological sample.Type: ApplicationFiled: March 15, 2013Publication date: September 18, 2014Applicant: I.D. THERAPEUTICS LLCInventors: Steven L. MAYER, David C. KRAVITZ, Tracey H. MAYER
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Patent number: 8609400Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate. The perfusion process can be automatically controlled using a control program.Type: GrantFiled: May 12, 2010Date of Patent: December 17, 2013Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Douglas Schein
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Publication number: 20130177897Abstract: A bag includes an organ transporter compartment to contain an organ transporter disposed in the transporter compartment. The bag may include openings to access portions of the organ transporter, such as a battery or power cable, when the organ transporter is disposed in the bag. The bag may also include a frame and handles. The handles may include structure adapted to mate with handles on the organ transporter. The bag may also include a single cover that provides access to multiple compartments with their own internal covers. Also, the bag may include windows to view documents stored in the bag and/or to view and/or display control panels on the organ transporter.Type: ApplicationFiled: January 11, 2012Publication date: July 11, 2013Applicant: LIFELINE SCIENTIFIC, INC.Inventors: David C. KRAVITZ, Peter DEMUYLDER, Brian OTTS, Stephan MERKLE, Jeremiah P. O'LEARY, Christopher E. SVENSRUD
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Patent number: 8445260Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. In perfusion, organ perfusion pressure is preferably controlled in response to a sensor disposed in an end of tubing placed in the organ, by a pneumatically pressurized medical fluid reservoir, providing perfusion pressure fine tuning, overpressurization prevention and emergency flow cut-off. In the hypothermic mode, the organ is perfused with a medical fluid, preferably a simple crystalloid solution containing antioxidants, intermittently or in slow continuous flow. The medical fluid may be fed into the organ from an intermediary tank having a low pressure head to avoid organ overpressurization. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate.Type: GrantFiled: August 10, 2011Date of Patent: May 21, 2013Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Douglas Schein, Stanley Harris, Dennis Steibel, Richard Fraser, Dickon Isaacs
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Patent number: 8431385Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures.Type: GrantFiled: January 21, 2011Date of Patent: April 30, 2013Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Douglas Schein
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Patent number: 8420381Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures.Type: GrantFiled: November 5, 2010Date of Patent: April 16, 2013Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Dennis J. Steibel, Richard Fraser, Stanley Harris, Douglas Schein
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Patent number: 8349551Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures. In the hypothermic mode, the organ is perfused with a medical fluid, preferably a simple crystalloid solution containing antioxidants, intermittently or in slow continuous flow. Viability of the organ may be automatically monitored, preferably by monitoring characteristics of the medical fluid perfusate. The perfusion process can be automatically controlled using a control program.Type: GrantFiled: November 5, 2010Date of Patent: January 8, 2013Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Dennis J. Steibel, Richard Fraser, Stanley Harris, Douglas Schein
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Patent number: 8323954Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures.Type: GrantFiled: March 29, 2011Date of Patent: December 4, 2012Assignee: Lifeline Scientific, Inc.Inventors: David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Douglas Schein
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Patent number: 8318415Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures.Type: GrantFiled: October 22, 2010Date of Patent: November 27, 2012Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Dickon Isaacs, Dennis J Steibel, Richard Fraser, Stanley Harris, Douglas Schein, Christopher G. Curtis
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Patent number: 8268612Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. Other apparatus include an organ transporter, an organ cassette and an organ diagnostic device. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures.Type: GrantFiled: August 10, 2011Date of Patent: September 18, 2012Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz, John Brassil, Kelvin G. M. Brockbank, Andrew Burroughs, Douglas Schein, Dickon Isaacs
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Patent number: 8268547Abstract: An organ perfusion apparatus and method monitor, sustain and/or restore viability of organs and preserve organs for storage and/or transport. The method includes perfusing the organ at hypothermic and/or normothermic temperatures, preferably after hypothermic organ flushing for organ transport and/or storage. The method can be practiced with prior or subsequent static or perfusion hypothermic exposure of the organ. Organ viability is restored by restoring high energy nucleotide (e.g., ATP) levels by perfusing the organ with a medical fluid, such as an oxygenated cross-linked hemoglobin-based bicarbonate medical fluid, at normothermic temperatures. In perfusion, organ perfusion pressure is preferably controlled in response to a sensor disposed in an end of tubing placed in the organ, by a pneumatically pressurized medical fluid reservoir, providing perfusion pressure fine tuning, overpressurization prevention and emergency flow cut-off.Type: GrantFiled: October 25, 2005Date of Patent: September 18, 2012Assignee: Lifeline Scientific, Inc.Inventors: Donald R. Owen, David C. Kravitz