Abstract: Novel cardiovascular prosthetic devices or implants having many useful cardiovascular applications comprise a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue forms a smooth thin adherent coating of self-determining thickness on the porous surface making it resistant to the formation of the blood clots normally associated with the presence of foreign bodies in the blood stream. The device has particular utility in heart valves, pacemaker electrodes, blood pumps, blood stream filters, an artificial pancreas, vascular access tubes, small and large bore vascular grafts, blood pump diaphragms and vascular and intracardiac patches.

Abstract: Implantable artificial blood pumps are described. The blood-contacting surfaces have pores therein which communicate with a subsurface of interconnected pores. This structure induces tissue formation thereon and avoidance of the incidence of thromboembolism.

Abstract: Novel cardiovascular prosthetic devices or implants having many useful cardiovascular applications comprise a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue forms a smooth thin adherent coating of self-determining thickness on the porous surface making it resistant to the formation of the blood clots normally associated with the presence of foreign bodies in the blood stream. The device has particular utility in heart valves, pacemaker electrodes, blood pumps, blood stream filters, an artificial pancreas, vascular access tubes, small and large bore vascular grafts, blood pump diaphragms and vascular and intracardiac patches.

Abstract: Novel cardiovascular prosthetic devices or implants having many useful cardiovascular applications comprise a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue forms a smooth thin adherent coating of self-determining thickness on the porous surface making it resistant to the formation of the blood clots normally associated with the presence of foreign bodies in the blood stream. The device has particular utility in heart valves, pacemaker electrodes, blood pumps, blood stream filters, an artificial pancreas, vascular access tubes, small and large bore vascular grafts, blood pump diaphragms and vascular and intracardiac patches.

Abstract: An endocardial pacemaker electrode is constructed of electroconductive metal inert to blood and consists of a dense rigid metal substrate and a rigid porous metal coating adhered to at least a major portion of the substrate. The electrode has a regular geometrical shape with a maximum transverse dimension of about 0.5 to 3 mm and a minimum longitudinal dimension of at least about 0.25 mm. The porous coating includes a plurality of metal particles bonded together at their points of contact with each other and with the substrate to form a network of interconnected pores substantially uniformly distributed throughout the coating. The porous coating has a porosity of about 10 to 50% by volume and a thickness of less than about 500 microns. The metal particles have a particle size selected from -100 +325 mesh, -325 +500 mesh and -500 mesh.

Abstract: A novel cardiovascular prosthetic device or implant having many useful cardiovascular applications comprises a porous surface and a network of interconnected interstitial pores below the surface in fluid flow communication with the surface pores. Tissue forms a smooth thin adherent coating of self-determining thickness on the porous surface making it resistant to the formation of the blood clots normally associated with the presence of foreign bodies in the blood stream.