Patents by Inventor David C. Montefiori

David C. Montefiori has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for reducing HIV-1 mother-to-child transmission by inducing V3-specific or CD4 binding site-specific antibodies
    Patent number: 11077130
    Abstract: The invention provides compositions and methods to induce and boost antibody response, including but not limited to IgG responses binding to HIV-1 in a subject in need thereof, wherein the induced/boosted plasma level of the antibody responses, for example V3 and/or CD4 binding site antibody responses, is over a threshold level and is associated with reduced risk of maternal-to-child-transmission (MTCT) of HIV-1.
    Type: Grant
    Filed: September 26, 2014
    Date of Patent: August 3, 2021
    Assignee: DUKE UNIVERSITY
    Inventors: Barton F. Haynes, Sallie Permar, M. Anthony Moody, Feng Gao, Hua-Xin Liao, Georgia Tomaras, David C. Montefiori
  • HIV-1 MOTHER-TO-CHILD TRANSMISSION CORRELATES OF PROTECTION AND VACCINE
    Publication number: 20160339051
    Abstract: The invention provides compositions and methods to induce and boost antibody response, including but not limited to IgG responses binding to HIV-1 in a subject in need thereof, wherein the induced/boosted plasma level of the antibody responses, for example V3 and/or CD4 binding site antibody responses, is over a threshold level and is associated with reduced risk of maternal-to-child-transmission (MTCT) of HIV-1.
    Type: Application
    Filed: September 26, 2014
    Publication date: November 24, 2016
    Inventors: Barton F. Haynes, Sallie Permar, M. Anthony Moody, Feng Gao, Hua-Xin Liao, Georgia Tomaras, David C. Montefiori
  • METHOD FOR THE GENERATION OF MONOCLONAL ANTIBODIES DERIVED FROM HUMAN B CELLS
    Publication number: 20130029424
    Abstract: The present invention relates, in general, to human B cells, and, in particular to a method of immortalizing and cloning human B cells and to monoclonal antibodies derived therefrom. The invention further relates to methods of using the monoclonal antibodies for therapeutic and diagnostic purposes.
    Type: Application
    Filed: April 11, 2011
    Publication date: January 31, 2013
    Inventors: Barton F. Haynes, Mattia Bonsignori, Kwan-Ki Hwang, Hua-Xin Liao, David C. Montefiori, Micah A. Luftig
  • Method of inhibiting replication of HIV with water-soluble melanins
    Patent number: 5057325
    Abstract: Replication of human immunodeficiency virus (HIV) is inhibited in human patients by administering melanins. L-dopa melanin is preferred, but other water-soluble melanins can be used.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: October 15, 1991
    Assignee: Vanderbilt University
    Inventor: David C. Montefiori