Patents by Inventor David C. Rupp

David C. Rupp has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Botulinum Neurotoxin Proteins and Methods to Engineer and Generate Same
    Publication number: 20230332126
    Abstract: Botulinum neurotoxin proteins and fragments thereof that bind and/or cleave a noncanonical substrate, e.g., non-neuronal SNARE proteins such as human SNAP-23 (hSNAP-23) and SNAP-29 (hSNAP-29), are described.
    Type: Application
    Filed: August 24, 2021
    Publication date: October 19, 2023
    Inventors: Gregory A. Weiss, Amy D. Brideau-Andersen, Rebekah P. Dyer, Lance E. Steward, Linh Q. Le, Gaetano Speciale, David C. Rupp, Birgitte P.S. Jacky, Madison H. Fletcher, Sudipta Majumdar
  • FORMULATIONS OF BIOLOGICS FOR INTRAVESICAL INSTILLATION
    Publication number: 20230256063
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Application
    Filed: September 16, 2022
    Publication date: August 17, 2023
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp, Terrence J. Hunt, Gary Shimizu, Joseph Francis, Ron S. Broide, Ester Fernandez-Salas, Catherine Rheaume
  • FORMULATIONS OF BIOLOGICS FOR INTRAVESICAL INSTILLATION
    Publication number: 20230256097
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Application
    Filed: September 26, 2022
    Publication date: August 17, 2023
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp
  • FORMULATIONS OF BIOLOGICS FOR INTRAVESICAL INSTILLATION
    Publication number: 20190022195
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Application
    Filed: April 16, 2018
    Publication date: January 24, 2019
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp, Terrence Hunt, Gary Shimizu, Joseph Francis, Ron S. Broide, Ester Fernandez-Salas
  • Formulations of biologics for intravesical instillation
    Patent number: 9943576
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Grant
    Filed: April 30, 2015
    Date of Patent: April 17, 2018
    Assignee: Allergan, Inc.
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp, Terrence Hunt, Gary Shimizu, Joseph Francis, Ron S. Broide, Ester Fernandez-Salas
  • Shaft seal assembly
    Patent number: 9845883
    Abstract: A shaft seal assembly for establishing a liquid-tight seal between a steering knuckle and an axle shaft is provided. The shaft seal assembly includes an outer case and a first elastomeric member attached to one another. The elastomeric member has a castellated feature including a plurality of projections extending in a radially outward direction and separated from one another by a plurality of grooves. When the shaft seal assembly is installed in the steering knuckle, a cavity is presented between the steering knuckle and the first elastomeric member. Together, the grooves and cavity allow air to flow from a hub on one side of the seal assembly to a vacuum port in the steering knuckle. The cavity extends circumferentially around the seal assembly, and thus, air flow from the hub to the vacuum port is not dependent upon the orientation of the seal assembly relative to the steering knuckle.
    Type: Grant
    Filed: June 8, 2012
    Date of Patent: December 19, 2017
    Assignee: Federal-Mogul LLC
    Inventors: Richard M. Larson, David C. Rupp, Reynaldo Fernandez, John Stark, Gerald A. Greca
  • FORMULATIONS OF BIOLOGICS FOR INTRAVESICAL INSTILLATION
    Publication number: 20160030570
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Application
    Filed: July 30, 2015
    Publication date: February 4, 2016
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp
  • FORMULATIONS OF BIOLOGICS FOR INTRAVESICAL INSTILLATION
    Publication number: 20150313973
    Abstract: Pharmaceutical formulations comprising a clostridial derivative and a permeabilizing agent for intravesical instillation are disclosed.
    Type: Application
    Filed: April 30, 2015
    Publication date: November 5, 2015
    Inventors: Eric A. Forssen, Patrick M. Hughes, David C. Rupp, Terrence Hunt, Gary Shimizu, Joseph Francis, Ron S. Broide, Ester Fernandez-Salas
  • SHAFT SEAL ASSEMBLY
    Publication number: 20120313328
    Abstract: A shaft seal assembly for establishing a liquid-tight seal between a steering knuckle and an axle shaft is provided. The shaft seal assembly includes an outer case and a first elastomeric member attached to one another. The elastomeric member has a castellated feature including a plurality of projections extending in a radially outward direction and separated from one another by a plurality of grooves. When the shaft seal assembly is installed in the steering knuckle, a cavity is presented between the steering knuckle and the first elastomeric member. Together, the grooves and cavity allow air to flow from a hub on one side of the seal assembly to a vacuum port in the steering knuckle. The cavity extends circumferentially around the seal assembly, and thus, air flow from the hub to the vacuum port is not dependent upon the orientation of the seal assembly relative to the steering knuckle.
    Type: Application
    Filed: June 8, 2012
    Publication date: December 13, 2012
    Inventors: Richard M. Larson, David C. Rupp, Reynaldo Fernandez, John Stark, Gerald A. Greca
  • Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
    Patent number: 5854303
    Abstract: A polymeric material incorporating a polyvalent cation chelating agent in an amount effective to inhibit the growth of an ocular pathogen, particularly a protozoan, can be used to produce eye care products such as contact lens cases and containers for containing eye care solutions and contact lenses.
    Type: Grant
    Filed: January 27, 1998
    Date of Patent: December 29, 1998
    Assignee: Allergan Sales, Inc.
    Inventors: Charles Hayes Powell, David C. Rupp
  • Polymer, article and method for inhibiting the growth of ocular pathogens in eye care products
    Patent number: 5739178
    Abstract: A polymeric material incorporating a polyvalent cation chelating agent in an amount effective to inhibit the growth of an ocular pathogen, particularly a protozoan, can be used to produce eye care products such as contact lens cases and containers for containing eye care solutions and contact lenses.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: April 14, 1998
    Assignee: Allergan
    Inventors: Charles Hayes Powell, David C. Rupp
  • Contact lens disinfecting compositions and methods employing terpenes
    Patent number: 5696171
    Abstract: A disinfecting composition for contact lenses includes an effective disinfecting amount of a terpene or combination of terpenes.
    Type: Grant
    Filed: August 30, 1994
    Date of Patent: December 9, 1997
    Assignee: Allergan, Inc.
    Inventors: David C. Rupp, Terrence J. Hunt
  • Method of inhibiting protozoan growth in eye care products using a polyvalent cation chelating agent
    Patent number: 5382599
    Abstract: A method for inhibiting the growth of protozoa in an eye care product is disclosed. The method includes the step of adding to the eye care product an effective protozoan growth-inhibiting amount of a polyvalent cation chelating agent. Methods are also disclosed for inhibiting the growth of protozoa on a surface of an eye care product by contacting the surface with a solution including an effective protozoan growth-inhibiting amount of a polyvalent cation chelating agent. Eye care products containing protozoan growth-inhibiting agents are also disclosed.
    Type: Grant
    Filed: October 13, 1993
    Date of Patent: January 17, 1995
    Assignee: Allergan, Inc.
    Inventors: David C. Rupp, Claude Anger, Saroj Kapadia, Mary Totaro