Patents by Inventor David C. S. Huang

David C. S. Huang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20100292200
    Abstract: The description discloses methods of enhancing or maintaining the viability or lifespan of platelets comprising administering an agent that down modulates apoptosis. The description also discloses a method of decreasing the survival, lifespan or viability of platelets comprising administering an effective amount of an agent that enhances apoptosis.
    Type: Application
    Filed: August 10, 2007
    Publication date: November 18, 2010
    Applicant: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Thomas Benjamin Kile, David C.S. Huang, Kylie D. Mason, Andrew Warwick Roberts, Marina Rose Carpinelli
  • Patent number: 7582439
    Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bim”, and to genetic sequences encoding same. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.
    Type: Grant
    Filed: April 24, 2006
    Date of Patent: September 1, 2009
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Suzanne Cory, Jerry Adams, David C. S. Huang, Liam O'Connor, Andreas Strasser, Hamsa Puthalakath, Lorraine O'Reilly
  • Publication number: 20080027145
    Abstract: The present invention relates generally to therapeutic molecules useful for inducing apoptosis of particular cells such as, but not limited to, cancer cells and methods for generating and/or selecting same. The present invention further provides methods for inducing apoptosis of cells such as cancer cells and pharmaceutical compositions useful for same. The present invention further provides methods for generating or selecting therapeutic agents capable of inducing apoptosis of particular cells by the selective inhibition of pro-survival proteins. The present invention further provides a computational approach to therapeutic molecule design based on structure-binding characteristics.
    Type: Application
    Filed: February 3, 2005
    Publication date: January 31, 2008
    Inventors: David C. S. Huang, Peter M. Colman, Catherine L. Day, Jerry M. Adams, Lin Chen, Simon N. Willis, Andrew Wei, Brian J. Smith, Mark G. Hinds
  • Patent number: 7064193
    Abstract: The present invention relates generally to novel molecules capable of, inter alia, modulating apoptosis in mammalian cells and to genetic sequences encoding same. More particularly, the present invention relates to a novel member of the Bcl-2 family of proteins, referred to herein as “Bim”, and to genetic sequences encoding same. The molecules of the present invention are useful, for example, in therapy, diagnosis, antibody generation and as a screening tool for therapeutic agents capable of modulating physiological cell death or survival and/or modulating cell cycle entry.
    Type: Grant
    Filed: September 17, 1998
    Date of Patent: June 20, 2006
    Assignee: The Walter and Eliza Hall Institute of Medical Research
    Inventors: Suzanne Cory, Jerry Adams, David C. S. Huang, Liam O'Connor, Andreas Strasser, Hamsa Puthalakath, Lorraine O'Reilly