Patents by Inventor David C. Sample

David C. Sample has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of isolating extract from the Euphorbia obesa plant and methods for using the same
    Patent number: 6923993
    Abstract: The present invention is directed to a process of isolating an extract from a Euphorbia obesa (EO) plant by: preparing a sample of said plant comprising removal of the latex material; dissolving said sample with first solvent to form a solution; separating said solution into a liquid and a pulp fraction; and purifying said pulp fraction. The isolated EO extract induces apoptosis and inhibits growth of a cancerous cell. Thus, the present invention is also directed to a method for inducing apoptosis and growth inhibition of a cancerous cell by contacting the cell with an effective amount of the EO extract by the process of the invention. Preferably, the extract is administered both to the tumor directly and intravenously. The preferred lines of cancerous cells are melanoma, non-small cell lung cancer, prostate cancer, breast carcinoma, ovarian cancer, lymphoma and leukemia cells.
    Type: Grant
    Filed: December 12, 2001
    Date of Patent: August 2, 2005
    Inventors: Nicholas D. Donato, Nicholas J. Donato, David C. Sample, Margot Perez, John S. McMurray, Robert A Newman
  • Method of isolating extract from the euphorbaciae obesa plant and methods for using the same
    Publication number: 20030118677
    Abstract: The present invention is directed to a process of isolating an extract from a Euphorbaciae obesa (EO) plant by: preparing a sample of said plant comprising removal of the latex material; dissolving said sample with first solvent to form a solution; seperating said solution into a liquid and a pulp fraction; and purifying said pulp fraction. The isolated EO extract induces apoptosis and inhibits growth of a cancerous cell. Thus, the present invention is also directed to a method for inducing apoptosis and growth inhibition of a cancerous cell by contacting the cell with an effective amount of the EO extract by the process of the invention. Preferably, the extract is administered both to the tumor directly and intravenously. The preferred lines of cancerous cells are melanoma, non-small cell lung cancer, prostate cancer, breast carcinoma, ovarian cancer, lymphoma and leukemia cells.
    Type: Application
    Filed: December 12, 2001
    Publication date: June 26, 2003
    Applicant: Credere Corporation
    Inventors: Nicholas D. Donato, Nicholas J. Donato, David C. Sample, Margot Perez, John S. McMurray, Robert A. Newman