Patents by Inventor David C. Sek

David C. Sek has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Protein Formulations Containing Sorbitol
    Publication number: 20080200655
    Abstract: The present invention provides a method for suppressing protein aggregation in a liquid formulation during freeze-thaw by including sorbitol in the liquid formulation. The present invention also provides methods for storing and preparing a liquid formulation containing a protein and sorbitol such that the presence of sorbitol suppresses protein aggregation during freezing and/or thawing.
    Type: Application
    Filed: February 15, 2008
    Publication date: August 21, 2008
    Applicant: Wyeth
    Inventor: David C. Sek
  • Use Of Sucrose To Suppress Mannitol-Induced Protein Aggregation
    Publication number: 20080200656
    Abstract: The present invention provides a method for suppressing mannitol-induced protein aggregation by providing sucrose to a liquid formulation containing a protein. The present invention also provides methods for storing and preparing a liquid formulation containing a protein and a combination of mannitol and sucrose such that the presence of sucrose suppresses mannitol-induced protein aggregation.
    Type: Application
    Filed: February 15, 2008
    Publication date: August 21, 2008
    Applicant: WYETH
    Inventors: David C. Sek, Nicholas W. Warne, Kin Ho, Donna L. Luisi, Angela Kantor
  • High Protein Concentration Formulations Containing Mannitol
    Publication number: 20080139792
    Abstract: The present invention provides a method for inhibiting mannitol-induced aggregation of a protein in a liquid formulation by increasing the protein concentration to an amount greater than 50 mg/ml. The present invention also provides methods for storing and preparing a liquid formulation containing mannitol and a protein concentration greater than 50 mg/ml.
    Type: Application
    Filed: December 5, 2007
    Publication date: June 12, 2008
    Applicant: WYETH
    Inventors: David C. Sek, Kin Ho