Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.

Abstract: Novel substituted quinazoline compounds and compositions for use in therapy as CSBP/p38 kinase inhibitors.

Abstract: Substituted quinazolinone compounds of formula (I) and compositions thereof for use in therapy as CSBP/p38 kinase inhibitors.

Abstract: The present invention relates to 4,4-disubstituted-3,4-dihydro-2(1H)-quinazolines of formula (1), or stereoisomeric forms, stereoisomeric mixtures, or pharmaceutically acceptable salt forms thereof, which are useful as inhibitors of HIV reverse transcriptase, and to pharmaceutical compositions and diagnostic kits comprising the same, and methods of using the same for treating viral infection or as an assay standard or reagent.

Abstract: The present invention is directed to the novel use of a CSBP/p38 inhibitor for the treatment, including prophylaxis of inflammation enhanced cough in a mammal in need thereof.

Abstract: The present invention is directed to the novel use of a CSBP/p38 inhibitor for the treatment, including prophylaxis of smoke induced pathology resulting from acute and chronic inflammation in the lung.

Abstract: Invention is a method of treating cough in a mammal, including a human, which comprises administering to such mammal an effective amount of an inhibitor of GABA uptake.

Abstract: Disclosed are concentrated alkaline liquid detergent compositions suitable for dilution with hard or de-ionized water. The compositions can be stored before and after dilution for prolonged periods at temperatures ranging from about 40.degree. F. (4.degree. C.) to about 100.degree. F. (38.degree. C.) without precipitates forming. The compositions contain a maleic acid-olefin copolymer, a detergent surfactant, a solvent/buffer system comprising beta-aminoalkanol and/or monoethanolamine, and less than about 85% water. The copolymer acts as a crystallization inhibitor and is uniquely soluble in the concentrated liquid detergent compositions.

Abstract: Aqueous, liquid hard surface detergent compositions having improved cleaning and good filming/streaking characteristics contain specific polycarboxylate detergent builders at critical levels. Preferred formulas contain a zwitterionic/anionic detergent surfactant mixture at levels (e.g., from about 0.02 to about 15%); hydrophobic solvent; alkaline material, especially volatile alkaline materials comprising monoethanolamine or certain beta-amino-alkanol compounds; and salt of ethylenediaminetetraacetic acid as the detergent builder in levels (e.g., from about 0.05% to about 0.5%, by weight of the composition).

Abstract: Aqueous, liquid hard surface detergent compositions contain zwitterionic and cationic detergent surfactants and monoethanolamine and/or other specific beta-aminoalkanols as solvents and/or buffers for improved spotting/filming and good cleaning. Some formulas do not contain large amounts of builders and are suitable for general purpose cleaning including cleaning of glass. Other formulas are concentrated and contain chelating agents (detergent builders) to improve stability of more dilute compositions prepared from the concentrated compositions. Some of the formulas, both dilute and concentrated, possess disinfectant properties.

Abstract: There is disclosed an air knife for preventing transfer of liquid from one container to another. The air knife comprises an expansion chamber having a product inlet opening on to one container and a product outlet opening onto a second container. Around the circumference of the expansion chamber is positioned a distribution chamber. Air is input to the distribution chamber through an air inlet and a large bore inlet and passes around the whole of the annular distribution chamber. Several evenly-spaced small bore inlets allow ingress of air from the distribution chamber into the expansion chamber. The air, at a pressure greater than the fluid outside the product inlet and product outlet is forced out of the product inlet and product outlet thus forcing liquid adhering to an elongate product, such as a strip of components being electroplated, passing from the product inlet through the expansion chamber and out of product outlet, off the elongate product.

Abstract: A process for hydrolyzing triglyceride having its carboxylic acid moieties containing from 6 to 26 carbon atoms involves reacting with water in the presence of low molecular weight displacing acid catalyst, strong acid catalyst and sufficient water to form water and oil phases, to produce carboxylic acids corresponding to said moieties and glycerine.

Abstract: Continuous, countercurrent flow, fluid-solid contacting process for the separation of more unsaturated fatty acid ester from a less unsaturated fatty acid ester in a mixture comprising the two types of esters. The solid adsorbent utilized in said process is a Type X or Type Y zeolite containing specified cations at the exchangeable cationic sites, and the desorbent is a mixture of a paraffinic hydrocarbon and an ether.