Patents by Inventor David C. Whitcomb

David C. Whitcomb has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 10174377
    Abstract: The present application discloses methods for predicting the risk of developing, or the presence of, recurrent acute pancreatitis and/or chronic pancreatitis, in a subject, by identifying the presence of an rs12688220 T allele, an rs7057398 T allele, and/or an rs10273639 C allele in a sample from the subject. The present application also discloses methods for treating or preventing pancreatitis in a human subject in need thereof.
    Type: Grant
    Filed: May 8, 2015
    Date of Patent: January 8, 2019
    Assignee: University Of Pittsburgh—Of The Commonwealth System Of Higher Education
    Inventor: David C. Whitcomb
  • Patent number: 9315867
    Abstract: The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
    Type: Grant
    Filed: November 4, 2010
    Date of Patent: April 19, 2016
    Assignees: UNIVERSITY OF WASHINGTON, UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL, THE CLEVELAND CLINIC FOUNDATION, UNIVERSITY OF PITTSBURG
    Inventors: Teresa A. Brentnall, Ru Chen, Katherine L. Pogue-Geile, David C. Whitcomb, Mary Patricia Bronner, Carol A. Otey
  • Publication number: 20150315649
    Abstract: The present application discloses methods for predicting the risk of developing, or the presence of, recurrent acute pancreatitis and/or chronic pancreatitis, in a subject, by identifying the presence of an rs12688220 C allele, an rs7057398 T allele, and/or an rs10273639 C allele in a sample from the subject. The present application also discloses methods for treating or preventing pancreatitis in a human subject in need thereof.
    Type: Application
    Filed: May 8, 2015
    Publication date: November 5, 2015
    Inventor: David C. Whitcomb
  • Publication number: 20110104694
    Abstract: The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
    Type: Application
    Filed: November 4, 2010
    Publication date: May 5, 2011
    Applicants: University of Washington, University of North Carolina at Chapel Hill, University of Pittsburgh, The Cleveland Clinic Foundation
    Inventors: Teresa A. Brentnall, Ru Chen, Katherine L. Pogue-Geile, David C. Whitcomb, Mary Patricia Bronner, Carol A. Otey
  • Patent number: 7851144
    Abstract: The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
    Type: Grant
    Filed: August 16, 2007
    Date of Patent: December 14, 2010
    Assignees: The University of Washington, The University of North Carolina at Chapel Hill, The University of Pittsburgh, The Cleveland Clinic Foundation
    Inventors: Teresa A. Brentnall, Ru Chen, Katherine L. Pogue-Geile, David C. Whitcomb, Mary Patricia Bronner, Carol A. Otey
  • Publication number: 20080318225
    Abstract: The present invention provides methods and compositions involving detecting the presence of and/or assessing the risk of cancer in a subject. These methods include methods of detecting and diagnosing cancer in an individual; methods of identifying individuals at risk of developing a cancer; and methods of staging a cancer. The methods generally involve detecting a palladin gene nucleotide sequence alteration that has been found to be associated with cancer and/or detecting a level of a palladin mRNA and/or protein in a biological sample. The present invention further provides nucleic acid probes, nucleic acid primers, and antibodies, as well as kits comprising one or more of the same, for use in a subject method.
    Type: Application
    Filed: August 16, 2007
    Publication date: December 25, 2008
    Inventors: Teresa A. Brentnall, Ru Chen, Katherine L. Pogue-Geile, David C. Whitcomb, Mary Patricia Bronner, Carol A. Otey