Abstract: The system and method for the creation of lyophilized beads using an automated or semi-automated system. The system can include a dispense head used in conjunction with a fluid system for dispensing a fluid containing a biological container. The dispense head can dispense droplets of fluid into a container containing a liquid coolant such as liquid nitrogen. The coolant can freeze the droplets solid, and you can dispense more beads into the system.

Abstract: This disclosure provides an isolated polypeptide therapeutics, polynucleotides encoding the polypeptides and antibodies that bind to the polypeptides are also provided. Therapeutic and diagnostic uses are further provided.

Abstract: A gravitational separation device is provided and the process is provided involving a packed column containing a packing material and having a device for vibrating the packed column and the particles. The gravitational separation device allows for efficient and effective separation of solid particles having different densities. The process preferably involves conditioning an aqueous pulp of mineral ore with a dispersant and feeding the dispersed aqueous pulp into an inlet into an intermediate section of the packed column and forming a high density bed of high density particles in a lower portion of the column, and forming a low density bed of low density particles in an upper portion of the column. Tailings are removed from the upper end of the column and concentrated mineral ore having reduced levels of gangue are removed from the bottom of the column.

Abstract: The froth flotation device includes a flotation column partially filled with a packing which defines a large number of small flow passages extending in a circuitous pattern between the upper and lower portions of the column. A conditioned aqueous pulp of a mineral ore, such as iron ore, is introduced into the midzone of the column. A pressurized inert gas, such as air, is introduced into the bottom of the column and is forced upwardly through the flow passages in the packing. As the air flows upwardly through these flow passages, it is broken into fine bubbles which intimately contact the floatable particles (e.g., iron oxide) in the aqueous pulp and forms a froth concentrate or float fraction which overflows from the top of the column. Wash water is introduced into the top of the column and flows through the flow passages in the packing countercurrently to the float fraction to scrub entrained non-floatable particles (e.g., gangue) from the froth concentrate.

Abstract: Iron oxides of finely-ground, low grade, siliceous oxidized iron ores can be effectively floated from the silica-bearing gangue in the presence of slime by conditioning an aqueous pulp of the ore with a reagent formed by incorporating a water-soluble polyvalent metal salt into an aqueous solution of an alkali metal silicate prior to subjecting the pulp to froth flotation in the presence of an anionic type collector.

Abstract: A high grade fraction is recovered from lithium-containing ores by conditioning a finely-ground aqueous pulp of the ore with a conditioning reagent formed by incorporating a water-soluble polyvalent metal salt into an aqueous solution of an alkali metal silicate and with an anionic collector and then subjecting the conditioned pulp, without desliming, to a froth flotation operation whereby a concentrate containing lithium and a tailing containing gangue are produced.