Patents by Inventor David Canter

David Canter has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and apparatus for screening and detecting multiple genetic mutations
    Patent number: 8772467
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Grant
    Filed: October 7, 2009
    Date of Patent: July 8, 2014
    Assignee: Gamida for Life B.V.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • METHODS AND APPARATUS FOR SCREENING AND DETECTING MULTIPLE GENETIC MUTATIONS
    Publication number: 20100167960
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Application
    Filed: October 7, 2009
    Publication date: July 1, 2010
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • Methods and apparatus for screening and detecting multiple genetic mutations
    Patent number: 7601493
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Grant
    Filed: July 24, 2003
    Date of Patent: October 13, 2009
    Assignee: Nanogen, Inc.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter
  • Methods and materials for optimization of electronic transportation and hybridization reactions
    Patent number: 7314542
    Abstract: Methods for the transport and hybridization of a nucleic acid on an electrode device by providing a low conductivity buffer with a reducing agent to the device. The low conductivity buffer may also contain a zwitterion. A current and voltage is applied to a location of the device to effect electrophoretic transportation of the nucleic acid towards the location. The nucleic acid is then hybridized to a nucleic probed located at the location. The reducing agent in the low conductivity buffer may also be acting as a chaotropic agent.
    Type: Grant
    Filed: September 22, 2005
    Date of Patent: January 1, 2008
    Assignee: Nanogen, Inc.
    Inventors: Daniel D. Smolko, Paul D. Swanson, Dalibor Hodko, David Canter, Robert W. Haigis, Tricia Patterson
  • Methods and materials for optimization of electronic transportation and hybridization reactions
    Publication number: 20060065531
    Abstract: Methods for the transport and hybridization of a nucleic acid on an electrode device by providing a low conductivity buffer with a reducing agent to the device. The low conductivity buffer may also contain a zwitterion. A current and voltage is applied to a location of the device to effect electrophoretic transportation of the nucleic acid towards the location. The nucleic acid is then hybridized to a nucleic probed located at the location. The reducing agent in the low conductivity buffer may also be acting as a chaotropic agent.
    Type: Application
    Filed: September 22, 2005
    Publication date: March 30, 2006
    Applicant: Nanogen, Inc
    Inventors: Daniel Smolko, Paul Swanson, Dalibor Hodko, David Canter, Robert Haigis, Tricia Patterson
  • Methods and apparatus for screening and detecting multiple genetic mutations
    Publication number: 20040146880
    Abstract: An assay system and methods are described where patient samples containing genomic DNA are analyzed for the presence of known genetic polymorphisms using a universal reporter strategy. In a preferred embodiment, the amplified DNA is localized at test sites in an array of sites on a microchip followed by a series of hybridization reactions that screen for the presence of a single mutation from among a number of mutations, and allow the identification of specific mutations. In addition to universal reporters, the assay may use blockers and discriminators for screening and identification of known polymorphisms.
    Type: Application
    Filed: July 24, 2003
    Publication date: July 29, 2004
    Applicant: Nanogen, Inc.
    Inventors: Ray R. Radtkey, Lance C. Held, Robert B. Wallace, Karen Menge, David Canter