Patents by Inventor David Castel

David Castel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20250213824
    Abstract: Various tube attachment device embodiments for attaching a tube, such as a medical drainage tube, to a patient to help stabilize or otherwise maintain the position of the tube in relation to the patient. One device embodiment includes a tube attachment ring comprising a lumen, an extendable clamp arm operably coupled to the tube attachment ring, and a base operably coupled to the tube attachment ring. Another implementation includes a device body comprising a first channel defined within the device body and a clamp body rotatably coupled to the device body, the clamp body comprising a second channel parallel with the first channel. Other aspects include methods of using any such device embodiment to attach a tube to a patient.
    Type: Application
    Filed: December 27, 2024
    Publication date: July 3, 2025
    Inventors: David Castel, Sigal Meilin
  • Publication number: 20240010990
    Abstract: The present invention concerns a novel in vitro assay for determining the invasive ability of brain tumour cells, in particular brain tumour stem cells. This new assay, called 3D invasion assay, is based on the analysis and comparison of the area of neurospheres grown in vitro into a Matrigel extracellular-like matrix. The invention also concerns the use of said assay for diagnosing metastatic brain tumour in subjects, for determining its prognosis, as well as for the monitoring, for the stratification, for identifying subjects at risk of metastasis, and/or predicting the metastasis-associated risk in subjects diagnosed with brain tumour.
    Type: Application
    Filed: September 14, 2021
    Publication date: January 11, 2024
    Applicant: Institut Gustave Roussy
    Inventors: David CASTEL, Marie Anne DEBILY, Jacques GRILL, Marco BRUSHI
  • Patent number: 10173056
    Abstract: The present invention is directed to methods for improving male fertility inter alia by increasing sperm count in a male subject. The methods of the invention comprise applying a positive electrical current below sensation level to at least one site of a scrotum of a subject in need thereof.
    Type: Grant
    Filed: July 11, 2013
    Date of Patent: January 8, 2019
    Assignee: Tel Hashomer Medical Research Infrastructure and Service Ltd.
    Inventors: Gil Raviv, David Shashar, Yoram Shadmi, Itzchak Shvitlowsky, David Castel
  • Publication number: 20150190632
    Abstract: The present invention is directed to methods for improving male fertility inter alia by increasing sperm count in a male subject. The methods of the invention comprise applying a positive electrical current below sensation level to at least one site of a scrotum of a subject in need thereof.
    Type: Application
    Filed: July 11, 2013
    Publication date: July 9, 2015
    Inventors: Gil Raviv, David Shashar, Yoram Shadmi, Itzchak Shvitlowsky, David Castel
  • Patent number: 4016878
    Abstract: A heater and humidifier for use with a breathing mask or other breathing apparatus, to avoid unpleasant and injurious effects of prolonged breathing of cold dry air, or other breathing gas mixture. The action is accomplished by injection and combustion of hydrogen directly in the breathing gas, and is carried out in a safe manner adjacent to or in the breathing mask. In addition to the heating effect, the hydrogen combines with oxygen in the breathing gas to produce moisture. The apparatus is adaptable to use under water, or in the atmosphere at any altitude and can be operated without a special power source.
    Type: Grant
    Filed: June 27, 1975
    Date of Patent: April 12, 1977
    Assignee: Foundation for Ocean Research
    Inventors: David Castel, Stephen E. Suess