Patents by Inventor David Chaplin

David Chaplin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20050160958
    Abstract: An apparatus and method for ballasting and de-ballasting a vessel having a hull with several watertight ballast compartments. In a first embodiment, a pressure tank is isolatably and fluidly coupled to a common sea chest, to the atmosphere, to ballast compartments via a distribution manifold, and to a source of compressed gas. The pressure tank is first vented and filled with water from the sea chest, then isolated. The filled tank is then coupled to a ballast tank and the source of compressed gas, which displaces water from the tank to the ballast compartment. In other embodiments, ballasting is by venting and flooding compartments using individual sea chests located within the ballast compartments or a firewater system. For de-ballasting, compressed gas displaces ballast water through overboard discharges, through the common sea chest via the pressure tank, or through individual sea chests located within the ballast compartments.
    Type: Application
    Filed: January 21, 2005
    Publication date: July 28, 2005
    Inventors: Terrence Kryska, David Chaplin
  • Publication number: 20050065595
    Abstract: The subject matter of this invention relates to implants, in particular intracavernous or intravascular implants, preferably for use in the treatment or prophylaxis of coronary or peripheral vascular occlusions or vascular narrowings or stenoses, in particular for use in the prophylaxis of a restenosis, which implants contain CA4 or CA4P in a chemically covalently or noncovalently bonded or a physically fixed form, and methods for the production and application thereof.
    Type: Application
    Filed: September 3, 2002
    Publication date: March 24, 2005
    Inventors: David Chaplin, Stephan Wnendt, Bernd Kuttler, Gunter Lorenz
  • Patent number: 6713517
    Abstract: Methods of killing tumor or cancer cells in human patients using an aryl N-substituted carboxamide having one or more aryl halo or one or more aromatic nitrogens, and/or acid addition salts thereof. The carboxamide may be an N-substituted nicotinamide or an N-substituted benzamide having such features, and may be used directly as a chemotherapeutic agent, or as a sensitizer for radiation or other chemotherapeutic agents. New compositions for such use include N-(2-diethylamino-ethyl)-4-amino-3-chlorobenzamide, N-(2-diethylamino-ethyl) nicotinamide, and their acid addition salts, e.g. hydrochlorides.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: March 30, 2004
    Assignee: OXiGENE, Inc.
    Inventors: Ronald W. Pero, Anders Olsson, Tomas Ekberg, Alan Schwartz, David Chaplin
  • Patent number: 6028111
    Abstract: The use of benzamide and nicotinamide analogs, in particular N-substituted benzamides and nicotinamides, other than benzamides with N-pyridinyl substitutions, as anti-inflammatory agents.
    Type: Grant
    Filed: February 27, 1997
    Date of Patent: February 22, 2000
    Assignee: OXiGENE, Inc.
    Inventors: Ronald W. Pero, David Chaplin