Abstract: Broadly speaking, embodiments of the present techniques provide techniques for generating haptic feedback or haptic sensations, and in particular to techniques for outputting haptic feedback which varies depending on the input. The haptic feedback is delivered by a shape memory alloy (SMA) actuator that controls the movement of a component based on the required haptic feedback/sensation.

Abstract: Broadly speaking, embodiments of the present techniques provide shape memory alloy (SMA) actuation apparatus for moving a moveable component relative to a static component or support structure and along a notional primary axis. The SMA actuation apparatus may comprise a biasing element to resist motion of the moveable component in particular directions relative to the primary axis, or may comprise an arrangement of SMA actuator wires that provides the biasing function.

Abstract: Methods and systems are provided authenticating transactions on a token contract. A transaction rule compliance engine that utilizes stored user information to ensure that transactions of tokens associated with the token contract comply with defined ruleset. A curation system maintains the stored user information on the token contract or elsewhere on the blockchain system.

Abstract: Methods and systems are provided for efficient distribution of digital assets according to a token contract defined by a rule set governing token ownership, transactions, and entitlements. A token contract audit system analyzes a ledger from a token contract to determine a balance for each of a plurality of users for the contract. A token distribution contract management system generates a distribution contract and publishes the contract to a distributed blockchain system to allow a subset of the plurality of users of the token contract to interact with the distribution contract.

Abstract: A device for depth mapping of an object comprises an emitter comprising a laser and an optical component, an actuator and a control processor unit. The actuator is arranged to change the relative position and/or relative orientation of the optical component to the laser. The control processor unit is configured to receive information relating to change in the location and/or orientation of the device during use of the device, and to instruct the actuator to change the relative position and/or relative orientation of the optical component to the laser so as to compensate for change in the location and/or orientation of the device during use of the device.

Abstract: Broadly speaking, embodiments of the present techniques provide apparatuses and methods for controlling the position and/or orientation of a moveable component of an actuator, using at least two shape memory alloy (SMA) actuator wires and at least one sensor for sensing position/orientation of the moveable component.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: A device for depth mapping of an object comprises an emitter comprising a laser and an optical component, an actuator and a control processor unit. The actuator is arranged to change the relative position and/or relative orientation of the optical component to the laser. The control processor unit is configured to receive information relating to change in the location and/or orientation of the device during use of the device, and to instruct the actuator to change the relative position and/or relative orientation of the optical component to the laser so as to compensate for change in the location and/or orientation of the device during use of the device.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of thrombin, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing a disease or disorder, which disease or disorder is amenable to treatment or prevention by the inhibition of thrombin.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.

Abstract: There are provided inter alia multisubstituted aromatic compounds useful for the inhibition of kallikrein, which compounds include substituted pyrazolyl or substituted triazolyl. There are additionally provided pharmaceutical compositions. There are additionally provided methods of treating and preventing certain diseases or disorders, which disease or disorder is amenable to treatment or prevention by the inhibition of kallikrein.