Abstract: Devices and methods for mapping tissue, such as cardiac tissue, and applying electrical energy to ablate the tissue may include an applicator region comprising two or more wire electrodes that extend between the arms of the device as well as a plurality of mapping and/or sensing electrodes (e.g., ring electrodes) on the arms and/or the elongate body. These devices may sense electrical activity using the mapping electrodes and may deliver energy between the first wire electrode and the second wire electrode to ablate, for example, cardiac tissue.

Abstract: A robotic surgical system can include one or more adjustable arm supports that support one or more robotic arms. The adjustable arm supports and/or robotic arms can be configured to be deployed from low mount positions, for example, from positions below the surface of the table. The robotic arms can include a plurality of joints providing a plurality of degrees of freedom. The joints may be grouped into a proximal shoulder, an elbow, and a distal wrist. The robotic arms can include one or more redundant degrees of freedom. An insertion mechanism, associated with the robotic arm and configured for providing insertion of an instrument along an assertion axis, can be provided at a distal end of the robotic arms.

Abstract: Compositions comprising an AhR agonist compound, such as indigo and/or an indigo derivative, such as indirubin and isatin, are described. Methods of treatment, including the treatment of ulcerative colitis, by administering the compositions are described. In an embodiment, compositions in the form of a solid amorphous dispersion of the AhR agonist are described.

Abstract: A flexible needle comprises a flexible body, an optical fiber, and a connector adapted for connecting the optical fiber to a processor. The flexible body comprises a wall including an interior surface defining a lumen. The wall further defines a securing feature. The securing feature is one of a channel within the wall, an external groove on an exterior surface of the wall, or an interior groove on an interior surface of the wall. The optical fiber is positioned at least partially within the securing feature. The flexible body further comprises a distal tip portion configured to pierce or puncture tissue.

Abstract: Provided herein are 6-carboxylic acids of benzimidazoles and 4-aza-, 5-aza-, 7-aza- and 4,7-diaza-benzimidazoles as GLP-1R agonists, processes to make said compounds, and methods comprising administering said compounds to a mammal in need thereof.

Abstract: A hot-stamped coated steel part includes a steel substrate and an aluminum alloy coating comprising, proceeding from steel substrate outwards, an interdiffusion layer and an outer layer. The total thickness of the coating ecoating and the thickness of the interdiffusion layer eIDL satisfy the following condition: 4 ? 0 ? E pc ? 80 ? with ? E pc = ( 3 ? 3 . 3 - e IDL 0 . 9 + e IDL - e coating ) 2 - 1 ? 4 ? 8 ? ( e IDL - e coating ) - ( 3 ? 3 . 3 - e IDL 0 . 9 + e IDL - e coating ) The hot-stamped coated steel part comprises an undeformed portion having a thickness ePflat from 0.6 mm to 3.5 mm, and at least one deformed portion. A lineic density of cracks dC in the coating in the undeformed portion is higher than or equal to a minimum lineic density of cracks dCmin(ePflat) defined as: dC m ? i ? n ( e pflat ) = 1 ? 5 . 5 + 9 ? 1 * e - 7.44 - 2 . 8 ? 8 * arctan ? ( 5.49 * ( e pflat - 1.

Abstract: An imaging system is provided that includes: a transmitter array; and a receiver array, wherein a transmission signal is transmitted from the transmitter array at an angle with respect to the receiver array, wherein the transmission signal is structured to focus at a region within 10-50 percent of a distance to the axis of rotation.

Abstract: A method can include receiving seismic data of a subsurface region; performing an iterative full waveform inversion using at least a portion of the seismic data to generate a model of the subsurface region, where the performing includes, after one or more iterations of the full waveform inversion, automatically selecting one or more parts of the seismic data for inclusion in the at least a portion of the seismic data based on data classification using one or more quality attributes; and outputting the model of the subsurface region.

Abstract: Bumpers for maintaining a gap between a light sheet and a translucent material in backlighting applications, as well as installation kits comprising light sheets and such bumpers. In some embodiments, the bumper comprises a base part having a central body, one or more bumper members, and at least one arm section which extends radially outward from the central body and connects to a respective bumper member opposite the central body. The central body may have an opening for receiving a fastener therethrough, with each bumper further comprising a cap part for covering the opening. Bumper member profiles are also specified with respect to height, radial extension, and convex curvature parameters.

Abstract: An example operation includes one or more of predicting, by a vehicle, a duration and a severity of an electrical-related event, determining, by the vehicle, a behavior profile of a group of devices at a location, based on a need of at least one of the group of devices during the event, and an amount of energy consumption of at least one of the group of devices during the event, predicting, by the vehicle, an energy requirement during the event at the location, based on the predicted duration, the predicted severity and the determined behavior profile, directing, by the vehicle, energy to be stored prior to the event by both the vehicle and an energy storage unit (ESU) associated with the location, and directing, by the vehicle, a flow of energy to the group of devices during the event, from the ESU and the vehicle.

Abstract: An aftertreatment temperature management system includes: an engine operative to combust a fuel; an aftertreatment system including an oxidation catalyst and operative to receive exhaust produced by the engine; a heat exchanger coupled to the aftertreatment system and operative to exchange heat between exhaust downstream of the oxidation catalyst and exhaust upstream of the oxidation catalyst; and an insulation at least partially enclosing the heat exchanger and the oxidation catalyst.

Abstract: Automatic generation of optimized aggregation metrics for usage-based insurance (UBI) includes performing a high-dimensional Bayesian optimization on a data archive, the data archive including a plurality of signals from vehicles and corresponding UBI effects, wherein the high-dimensional Bayesian optimization includes performing testing on weighted groups of the plurality of signals using one or more aggregation functions; and transmitting the one or more aggregation functions to a vehicle to cause the vehicle to provide aggregated signals for input to a UBI model to predict a UBI rate for the vehicle.

Abstract: Disclosed are methods, systems, and non-transitory computer readable memory for processing, analyzing, and visualizing complex digital object sets using large language models. For instance, a method may include receiving a set of digital objects; indexing the received set of digital objects to generate indexed data; generating a timeline prompt based on the indexed data; processing the timeline prompt to generate a timeline response; and outputting the timeline response as an interactive timeline of based on the set of digital objects.

Abstract: Methods and systems are described herein for inspection of a workpiece, such as a honeycomb body. The methods and systems include collecting a plurality of images of the honeycomb body, extracting measurement data from each of the plurality of images, converting the measurement data extracted from each image into a common frame of reference, and combining the measurement data together.

Abstract: Game information for a wagering game is received from a remote gaming table. Live actions by a live dealer for the wagering game are captured by an image capture device. Image information based on the captured live actions are transmitted to the remote gaming table to provide a live holographic image of the dealer at the remote gaming table. An input device receives game input from the live dealer and game instructions based on the game input are transmitted to the remote gaming table to execute game actions at the remote gaming table to generate a game result for the wagering game.

Abstract: The present teaching relates to system, method, medium for in-situ perception in an autonomous driving vehicle. A plurality of types of sensor data acquired continuously by a plurality of types of sensors deployed on the vehicle are first received, where the plurality of types of sensor data provide information about surrounding of the vehicle. Based on at least one model, one or more items are tracked from a first of the plurality of types of sensor data acquired by one or more of a first type of the plurality of types of sensors, wherein the one or more items appear in the surrounding of the vehicle. At least some of the one or more items are then automatically labeled on-the-fly via either cross modality validation or cross temporal validation of the one or more items and are used to locally adapt, on-the-fly, the at least one model in the vehicle.

Abstract: As part of a dialog session between a user and an automated assistant, implementations can process, using a streaming ASR model, a stream of audio data to generate ASR output, process, using an NLU model, the ASR output to generate NLU output, and generate, based on the NLU output, a stream of fulfillment data. Further, implementations can further determine, based on processing the stream of audio data, audio-based characteristics associated with spoken utterance(s) captured in the stream of audio data. Based on a current state of the stream of NLU output, the stream of fulfillment data, and the audio-based characteristics, implementations can determine whether a next interaction state to be implemented is: (i) causing fulfillment output to be implemented; (ii) causing natural conversation output to be audibly rendered; or (iii) refrain from causing any interaction to be implemented, can cause the next interaction state to be implemented.

Abstract: A federated distributed computational system enables secure collaboration across multiple institutions for multi-species biological data analysis. The system consists of interconnected computational nodes managed by a central federation manager. Each node contains specialized components that work together to process multi-species biological data while preserving privacy. These components include a local computational engine that handles data processing, a physics-information integration subsystem that combines physical state calculations with information-theoretic optimization, a privacy preservation module that protects sensitive information, a knowledge integration component that manages biological data relationships, and a communication interface that enables secure information exchange between nodes. The federation manager coordinates all computational activities and manages resource allocations across the network while ensuring data privacy is maintained throughout the process.

Abstract: The present invention relates to a system and a method implemented by an intelligent module. The system comprises an interface, an artificial intelligence module, and an intelligent flow framework module. The intelligent flow framework module is communicatively coupled to the interface and the artificial intelligence module. The intelligent flow framework module is configured to define at least one task based on an event and contextual data for completing a mission. The system provides the ability to adapt quickly to changing circumstances and make intelligent decisions to ensure the successful completion of missions/objectives.

Abstract: A bearing assembly for a linear electromagnetic machine includes a sleeve having a surface configured to provide a bearing between the surface and a translator, a front plate coupled to the sleeve, a support block, and a plurality of flexures coupled to the support block. Each flexure is coupled between the support block and one of the front plate or a stator. For example, a load path extends from a stator to the support block via a first set of flexures of the plurality of flexures, from the support block to the front plate via a second set of flexures of the plurality of flexures, and from the front plate to the sleeve. In the example of four flexures, two flexures are affixed to the support block and front plate, while two other flexures are affixed to the support block and the stator.