Abstract: A parking brake system for vehicles, in particular heavy-duty vehicles, is provided. The parking brake system has a parking brake actuator having an actuation pushrod slidably housed within an actuator cylinder and adapted to act on a release mechanism of a vehicle brake for unlocking the vehicle brake, and a hydraulic pump operated by an electric motor, adapted to deliver a flow of fluid into the actuator cylinder for moving the actuation pushrod.

Abstract: Methods are provided herein for selectively killing senescent cells and for treating senescence-associated diseases and disorders by administering a senolytic agent. Senescence-associated diseases and disorders treatable by the methods using the senolytic agents described herein include cardiovascular diseases and disorders associated with or caused by arteriosclerosis, such as atherosclerosis; idiopathic pulmonary fibrosis; chronic obstructive pulmonary disease; osteoarthritis; senescence-associated ophthalmic diseases and disorders; and senescence-associated dermatological diseases and disorders.

Abstract: This invention establishes a new paradigm for treatment of Parkinson's disease (PD) by eliminating senescent cells that reside in or around the site of the disease pathophysiology. Exposure of test subjects to the herbicide paraquat (PQ) increases the risk for developing Parkinson's disease. The data in this disclosure show that PQ induces a senescence arrest and SASP in astrocytes, in culture and in vivo in mice, and senescent cell markers were present in astrocytes in midbrain tissue from PD patients. In a transgenic mouse model, senescent cell ablation protected against PQ-induced PD-like neuropathology. Removal of senescent cells from affected sites using small molecule agents that specifically target senescent cells can help prevent or ameliorate signs and symptoms of the disease.

Abstract: An aircraft includes external structures, and one or more thermal emitters integrated with one or more of the external structures. The one or more thermal emitters are configured to generate heat to deice the one or more external structures. The one or more thermal emitters are configured to receive electrical power from one or more of an auxiliary power unit of the aircraft, a power distribution system of the aircraft, one or more engines of the aircraft, or an external power cart that is separate and distinct from the aircraft.

Abstract: An electrical contact for a semiconductor device, and a method of forming an electrical contact is disclosed. The electrical contact comprises a perimeter area, an aperture located within the perimeter area and one or more electrical tracks extending from the perimeter area into the aperture. The one or more electrical tracks comprise a non-linear shape. The presence of the one or more electrical tracks within the aperture provides a means to remove, or significantly reduce, the problematic effects of current crowding within a semiconductor device in which it is employed. The electrical contacts provide particular application for semiconductor laser devices. When the electrical contact is located on an output surface of the semiconductor laser device, the condition for a diffraction pattern to be imparted onto the emission profile of the output light of the semiconductor laser device is removed, thus improving the overall beam quality of the output light.

Abstract: Systems and methods for wire arc additive manufacturing systems that print in horizontal orientations are described. Horizontal WAAM 3D print systems comprise metal 3D print systems in a horizontal orientation with one or more robots operating concurrently on a work piece using one or more wire feeds and a rotating, horizontal build plate.

Abstract: The use of ion-conducting materials to protect electrodes is generally described. The ion-conducting material may be in the form of a layer that is adjacent to a polymeric layer, such as a porous separator, to form a composite. At least a portion of the pores of the polymer layer may be filled or unfilled with the ion-conducting material. In some embodiments, the ion-conducting layer is sufficiently bonded to the polymer layer to prevent delamination of the layers during cycling of an electrochemical cell.

Abstract: According to the invention there is provided a method of processing a mixture of minerals including the steps of: (a) providing a mixture of minerals which includes a metal containing mineral and one or more unwanted gangue minerals; (b) achieving a contact between the mixture of minerals and polymeric material that includes a mineral binding moiety which selectively binds to the metal containing mineral; and (c) separating the gangue minerals and the polymeric material which has the metal containing mineral bound thereto.

Abstract: Composite structures including an ion-conducting material and a polymeric material (e.g., a separator) to protect electrodes are generally described. The ion-conducting material may be in the form of a layer that is bonded to a polymeric separator. The ion-conducting material may comprise a lithium oxysulfide having a lithium-ion conductivity of at least at least 10?6 S/cm.

Abstract: Methods for laser cutting electrodes and electrodes with modified edges are generally described.

Abstract: Composite structures including an ion-conducting material and a polymeric material (e.g., a separator) to protect electrodes are generally described. The ion-conducting material may be in the form of a layer that is bonded to a polymeric separator. The ion-conducting material may comprise a lithium oxysulfide having a lithium-ion conductivity of at least at least 10?6 S/cm.

Abstract: The use of ion-conducting materials to protect electrodes is generally described. The ion-conducting material may be in the form of a layer that is adjacent to a polymeric layer, such as a porous separator, to form a composite. At least a portion of the pores of the polymer layer may be filled or unfilled with the ion-conducting material. In some embodiments, the ion-conducting layer is sufficiently bonded to the polymer layer to prevent delamination of the layers during cycling of an electrochemical cell.

Abstract: Systems and methods related to cutting (e.g., ultrasonically cutting) metals (e.g., lithium metal) and electrode precursors are generally provided. The electrodes or electrode precursors may involve, for example, a lithium metal electrode or a lithium composite electrode, e.g., for use in an electrochemical cell or battery.

Abstract: The use of ion-conducting materials to protect electrodes is generally described. The ion-conducting material may be in the form of a layer that is adjacent to a polymeric layer, such as a porous separator, to form a composite. At least a portion of the pores of the polymer layer may be filled or unfilled with the ion-conducting material. In some embodiments, the ion-conducting layer is sufficiently bonded to the polymer layer to prevent delamination of the layers during cycling of an electrochemical cell.

Abstract: A laser device has a photonic crystal surface emitting laser (PCSEL) element. At a first lateral side of the PCSEL element, a reflector is arranged to reflect back into the PCSEL element at least a portion of light travelling out of the PCSEL element through the first lateral side of the PCSEL element. Between the first lateral side of the PCSEL element and the reflector there is interposed an electrically controllable light-transmission region configured to control the transmission of light from the PCSEL element to the reflector, based on an electrical input. Also disclosed is a method of operation of a corresponding laser device.

Abstract: Lithium metal electrodes, modular lithium deposition systems, and associated articles and methods are generally described.

Abstract: Systems and methods related to cutting electrodes (e.g. lithium metal) and electrode precursors are generally provided. The electrodes or electrode precursors may involve, for example, a lithium metal electrode or a lithium composite electrode, e.g., for use in an electrochemical cell or battery.

Abstract: A method for improving privacy of security cameras is described. In one embodiment, predetermined events are monitored via a security camera. The security camera may include an optical barrier. At least one of the predetermined events is detected via the security camera. Based on detecting at least one of the predetermined events, the optical barrier is repositioned, via the security camera, in relation to a camera lens of the security camera.

Abstract: Methods and systems are described for detecting a premise condition. According to at least one embodiment, a method for detecting a premise condition includes detecting a sound with a security system component, determining with the security system component whether the sound belongs to a recognized class of sounds, sending the recognized class to a remote control unit, and causing with the remote control unit a predetermined response to occur based on the recognized class.

Abstract: According to the invention there is provided a method of processing a mixture of minerals including the steps of: (a) providing a mixture of minerals which includes a metal containing mineral and one or more unwanted gangue minerals; (b) achieving a contact between the mixture of minerals and polymeric material that includes a mineral binding moiety which selectively binds to the metal containing mineral; and (c) separating the gangue minerals and the polymeric material which has the metal containing mineral bound thereto.