Abstract: A printed article prepared by a flexographic printing process by applying a coating or ink that contains materials that are highly reactive with hydroxyl groups to an article substrate using a flexographic roller or plate made of non-polar polymers and optionally impregnated with silicone. In addition, a flexographic process for preparing a printed article by pattern applying more than one type of coating onto an article substrate. Unique patterns are laser engraved onto non-polar polymeric flexographic rollers/plates that may be impregnated with silicone, to preferably each coat different portions of the article substrate surface.