Patents by Inventor David Colclough

David Colclough has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Nitric oxide synthase inhibitor phosphate salt
    Patent number: 7317040
    Abstract: A compound of formula (I): namely (2S)-2-amino-4-{[2-(ethanimidoylamino)ethyl]thio}butanoic acid, compound with phosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relatively non-hygroscopic selective inhibitor of inducible nitric oxide synthase.
    Type: Grant
    Filed: December 17, 2001
    Date of Patent: January 8, 2008
    Assignee: SmithKline Beecham Corporation
    Inventors: David Box, David Colclough, Iain Gillies, Michael Simon Loft, Rebecca Moore
  • Nitric oxide synthase inhibitor phosphate salt
    Publication number: 20040087654
    Abstract: A compound of formula (I): namely (2S)-2-amino-4-{[2-(etha-nimidoylamino)ethyl]thio}butanoic acid, compound with prosphoric acid, or a solvate or physiologically functional derivative thereof, is useful as a relatively non-hygroscopic selective inhibitor of inducible nitric oxice synthase.
    Type: Application
    Filed: November 11, 2003
    Publication date: May 6, 2004
    Inventors: David Box, David Colclough, Iain Gillies, Michael Simon Loft, Rebecca Moore
  • Chemical process
    Patent number: 6673921
    Abstract: A process for the preparation of the compound (I) or an acid addition salt thereof which comprises reacting a compound of formula (II), wherein R is an optionally substituted benzyl group under concomitant reduction and hydrogenolysis conditions, followed, if required, by isolation of the compound as an acid addition salt thereof.
    Type: Grant
    Filed: February 19, 2003
    Date of Patent: January 6, 2004
    Assignee: SmithKline Beecham Corporation
    Inventors: David Colclough, Anne Hodgson
  • Chemical process
    Publication number: 20030158082
    Abstract: A process for the preparation of the compound (1) or an acid addition salt thereof which comprises reacting a compound of formula (II), wherein R is an optionally substituted benzyl group under concomitant reduction and hydrogenolysis conditions, followed, if required, by isolation of the compound as an acid addition salt thereof.
    Type: Application
    Filed: February 19, 2003
    Publication date: August 21, 2003
    Inventors: David Colclough, Anne Hodgson