Patents by Inventor David Coomber
David Coomber has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9706273Abstract: The invention relates to a method for auto-configuring a wavelength selective switch (WSS) device having an output port and a plurality of input ports and coupled to a WSS controller. When connected to a WDM optical network, the WSS controller is programmed to utilize one or more optical channel monitors (OCM) coupled to the input and/or output ports to detect which of the wavelengths are present at the input ports. Wavelengths that are not detected on any input port are blocked by the WSS. Any wavelength detected as present at one and only one input port is switched by the WSS to the output port. If a wavelength is detected at two or more input ports, it is either blocked by the WSS at each of the input ports until user intervention, or is blocked at all but one of the input ports as defined by assigned port priorities.Type: GrantFiled: January 29, 2015Date of Patent: July 11, 2017Assignee: Lumentum Operations LLCInventors: Thomas Haslam, David Coomber, Daniel Doliska, Michael Scott Pegrum, Marc-Antoine Boutin, Brian Sungwan Kim
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Publication number: 20150139643Abstract: The invention relates to a method for auto-configuring a wavelength selective switch (WSS) device having an output port and a plurality of input ports and coupled to a WSS controller. When connected to a WDM optical network, the WSS controller is programmed to utilize one or more optical channel monitors (OCM) coupled to the input and/or output ports to detect which of the wavelengths are present at the input ports. Wavelengths that are not detected on any input port are blocked by the WSS. Any wavelength detected as present at one and only one input port is switched by the WSS to the output port. If a wavelength is detected at two or more input ports, it is either blocked by the WSS at each of the input ports until user intervention, or is blocked at all but one of the input ports as defined by assigned port priorities.Type: ApplicationFiled: January 29, 2015Publication date: May 21, 2015Inventors: Thomas HASLAM, David Coomber, Daniel Doliska, Michael Scott Pegrum, Marc-Antoine Boutin, Brian Sungwan Kim
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Patent number: 8948592Abstract: The invention relates to a method for auto-configuring a wavelength selective switch (WSS) device having an output port and a plurality of input ports and coupled to a WSS controller. When connected to a WDM optical network, the WSS controller is programmed to utilize one or more optical channel monitors (OCM) coupled to the input and/or output ports to detect which of the wavelengths are present at the input ports. Wavelengths that are not detected on any input port are blocked by the WSS. Any wavelength detected as present at one and only one input port is switched by the WSS to the output port. If a wavelength is detected at two or more input ports, it is either blocked by the WSS at each of the input ports until user intervention, or is blocked at all but one of the input ports as defined by assigned port priorities.Type: GrantFiled: March 1, 2010Date of Patent: February 3, 2015Assignee: JDS Uniphase CorporationInventors: Thomas Haslam, David Coomber, Daniel Doliska, Michael Scott Pegrum, Marc-Antoine Boutin, Brian Sungwan Kim
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Patent number: 8679781Abstract: The invention provides a method for making in vitro peptide expression libraries, and for the isolation of nucleotide sequences encoding peptides of interest, wherein the peptides or proteins are specifically associated with the DNA encoding them through non-covalent protein:DNA binding. The method describes ways of making the library itself, DNA molecules encoding the library and uses of the expression library.Type: GrantFiled: October 21, 2010Date of Patent: March 25, 2014Assignee: Isogenica LimitedInventors: Duncan McGregor, Richard Odegrip, Kevin Fitzgerald, Rosemarie Hederer, Bill Eldridge, Chris Ullman, Philip Kuhlman, David Coomber
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Patent number: 8557744Abstract: A method is selects membrane-translocating peptides (MTPs) from a peptide display library that are capable of crossing or penetrating a lipid membrane. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of nucleic acid-peptide complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide; the complexes are exposed to a population of membrane-encapsulated compartments, allowing a translocating reaction to occur; complexes that remain unassociated with the membrane are removed; optionally complexes that are associated with the membrane are removed; and internalized nucleic acid-peptide complexes are recovered. The membrane-encapsulated compartments may be artificial vesicles such as liposomes, or populations of one or more cell types.Type: GrantFiled: July 24, 2006Date of Patent: October 15, 2013Assignee: Isogenica Ltd.Inventors: David Coomber, Kevin Fitzgerald, Duncan McGregor, Chris Ullman, Tomas Leanderson
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Publication number: 20120149591Abstract: The invention provides a method for making in vitro peptide expression libraries, and for the isolation of nucleotide sequences encoding peptides of interest, wherein the peptides or proteins are specifically associated with the DNA encoding them through non-covalent protein:DNA binding. The method describes ways of making the library itself, DNA molecules encoding the library and uses of the expression library.Type: ApplicationFiled: October 21, 2010Publication date: June 14, 2012Applicant: ISOGENICA LIMITEDInventors: Duncan MCGREGOR, Richard ODEGRIP, Kevin FIZGERALD, Rosemarie HEDERER, Bill ELDRIDGE, Chris ULLMAN, Philip KUHLMAN, David COOMBER
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Patent number: 7932873Abstract: An apparatus includes a light source configured to provide a path of light and a spatial light modulator located in the path of light and configured to modulate the light source. Relay optics are configured to receive the modulated light from the spatial light modulator and to project a computer generated image to a nominal image plane. The light source is configured to illuminate the spatial light modulator with collimated light.Type: GrantFiled: July 6, 2010Date of Patent: April 26, 2011Assignee: F. Poszat Hu, LLCInventors: Mark Anthony Gleeson Smith, Stuart David Coomber, Andrew Crow
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Patent number: 7842476Abstract: The invention provides a method for making in vitro peptide expression libraries, and for the isolation of nucleotide sequences encoding peptides of interest, wherein the peptides or proteins are specifically associated with the DNA encoding them through non-covalent protein:DNA binding. The method describes ways of making the library itself, DNA molecules encoding the library and uses of the expression library.Type: GrantFiled: September 5, 2003Date of Patent: November 30, 2010Assignee: Isogenica LimitedInventors: Duncan McGregor, Richard Odegrip, Kevin Fizgerald, Rosemarie Hederer, Bill Eldridge, Chris Ullman, Philip Kuhlman, David Coomber
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Publication number: 20100271677Abstract: An apparatus includes a light source configured to provide a path of light and a spatial light modulator located in the path of light and configured to modulate the light source. Relay optics are configured to receive the modulated light from the spatial light modulator and to project a computer generated image to a nominal image plane. The light source is configured to illuminate the spatial light modulator with collimated light.Type: ApplicationFiled: July 6, 2010Publication date: October 28, 2010Applicant: F. POSZAT HU, LLCInventors: Mark Anthony Gleeson Smith, Stuart David Coomber, Andrew Crow
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Patent number: 7791560Abstract: An apparatus includes a light source configured to provide a path of light and a spatial light modulator located in the path of light and configured to modulate the light source. Relay optics are configured to receive the modulated light from the spatial light modulator and to project a computer generated image to a nominal image plane. The light source is configured to illuminate the spatial light modulator with collimated light.Type: GrantFiled: January 29, 2008Date of Patent: September 7, 2010Inventors: Mark Anthony Gleeson Smith, Stuart David Coomber, Andrew Crow
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Publication number: 20100221004Abstract: The invention relates to a method for auto-configuring a wavelength selective switch (WSS) device having an output port and a plurality of input ports and coupled to a WSS controller. When connected to a WDM optical network, the WSS controller is programmed to utilize one or more optical channel monitors (OCM) coupled to the input and/or output ports to detect which of the wavelengths are present at the input ports. Wavelengths that are not detected on any input port are blocked by the WSS. Any wavelength detected as present at one and only one input port is switched by the WSS to the output port. If a wavelength is detected at two or more input ports, it is either blocked by the WSS at each of the input ports until user intervention, or is blocked at all but one of the input ports as defined by assigned port priorities.Type: ApplicationFiled: March 1, 2010Publication date: September 2, 2010Inventors: Thomas Haslam, David Coomber, Daniel Doliska, Michael Scott Pegrum, Marc-Antoine Boutin, Brian Sungwan Kim
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Publication number: 20080287311Abstract: A method is provided for selecting membrane-translocating peptides (MTPs) from a peptide display library that are capable of crossing or penetrating a lipid membrane. A plurality of nucleic acid constructs that encode displayed peptides are expressed, resulting in the formation of a plurality of nucleic acid-peptide complexes, each complex comprising at least one displayed peptide associated with the corresponding nucleic acid construct encoding the displayed peptide; the complexes are exposed to a population of membrane-encapsulated compartments, allowing a translocating reaction to occur; complexes that remain unassociated with the membrane are removed; optionally complexes that are associated with the membrane are removed; and internalised nucleic acid-peptide complexes are recovered. The membrane-encapsulated compartments may be artificial vesicles such as liposomes, or populations of one or more cell types.Type: ApplicationFiled: July 24, 2006Publication date: November 20, 2008Applicant: Isogenica Ltd.Inventors: David Coomber, Kevin Fitzgerald, Duncan McGregor, Chris Ullman, Tomas Leanderson
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Publication number: 20080247013Abstract: An apparatus includes a light source configured to provide a path of light and a spatial light modulator located in the path of light and configured to modulate the light source. Relay optics are configured to receive the modulated light from the spatial light modulator and to project a computer generated image to a nominal image plane. The light source is configured to illuminate the spatial light modulator with collimated light.Type: ApplicationFiled: January 29, 2008Publication date: October 9, 2008Applicant: F. POSZAT HU, LLCInventors: Mark Anthony Gleeson Smith, Stuart David Coomber, Andrew Crow
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Publication number: 20080211836Abstract: A system includes a driving apparatus configured to operate on an optically addressed spatial light modulator (OASLM) including a modulation layer notionally divided into a plurality of separately addressable segments. A pulse generator is configured to provide one or more voltage patterns and an optical pattern generator configured to provide one or more optical patterns of light. For each segment of the OASLM, the driving apparatus is further configured to write, over a predetermined number of write operations, a predetermined amount of light associated with the one or more optical patterns. The driving apparatus is configured to apply a reset pulse associated with the one or more voltage patterns, such that a resulting net charge on the modulation layer is zero.Type: ApplicationFiled: February 8, 2008Publication date: September 4, 2008Applicant: F. POSZAT HU, LLCInventors: Maurice STANLEY, Stuart David Coomber
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Patent number: 7265893Abstract: A method of controlling the switching of an optically addressable spatial light modulator (OASLM), to a first surface of which a write light signal is applied and to a second surface of which a read light signal is applied. The method comprises applying a bipolar switching waveform to control electrodes of the (OASLM) during each write cycle such that the leading pulse of the waveform applies a voltage across the (OASLM) which is in the photosensitive direction and the trailing pulse applies a voltage which is not in the photosensitive direction.Type: GrantFiled: October 6, 2003Date of Patent: September 4, 2007Assignee: Qinetiq LimitedInventors: Jonathan Rennie Hughes, Stuart David Coomber, Carl Vernon Brown, Alexander John Topping
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Publication number: 20070128672Abstract: The present invention relates to nucleotide sequences which encode polypeptides of antibodies against the p53 protein in vertebrates, and to the polypeptides and antibodies (or fragments thereof) encoded by those nucleotide sequences. The invention also relates to nucleotide sequences and polypeptide sequences for use in the development of diagnostic and therapeutic compositions, and to methods of using those diagnostic and therpeutic compositions in the diagnosis and treatment of cancer, rheumatoid arthritis and other disease states which exhibit abnormalities of p53.Type: ApplicationFiled: May 31, 2006Publication date: June 7, 2007Applicant: ST. VINCENT'S HOSPITAL SYDNEY LIMITEDInventors: Robyn Ward, David Coomber
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Publication number: 20060035232Abstract: The invention provides a method for making in vitro peptide expression libraries, and for the isolation of nucleotide sequences encoding peptides of interest, wherein the peptides or proteins are specifically associated with the DNA encoding them through non-covalent protein:DNA binding. The method describes ways of making the library itself, DNA molecules encoding the library and uses of the expression library.Type: ApplicationFiled: September 5, 2003Publication date: February 16, 2006Inventors: Duncan McGregor, Richard Odegrip, Kevin Fizgerald, Rosemarie Hederer, Bill Eldridge, Chris Ullman, Philip Kuhlman, David Coomber