Abstract: Aspects of the disclosure are directed to methods and compositions for treating or preventing an allergic airway disease in a subject in need thereof. Certain aspects relate to treatment with an effective amount of a composition comprising one or more Dickkopf-1 (Dkk-1) inhibitors and/or one or more additional allergic airway disease therapies. Further aspects relate to methods of reducing airway inflammation, reducing airway hyper-responsiveness, and/or inhibiting an adaptive or innate immune response in the airway of a subject comprising administering to the subject an effective amount of a composition comprising one or more Dkk-1 inhibitors and/or one or more additional allergic airway disease therapies.

Abstract: A pipe carrier in an embodiment includes a pipe-carrying region in which forward and rear pipe lifting assemblies are arranged to lift and carry a pipe section. For example, the pipe-carrying region lies rearwards of the front traveling support of the pipe carrier, and forwards of the rear traveling support of the pipe carrier. The pipe carrier includes a modular extension assembly carrying an energy source for powering the pipe carrier, wherein the energy source is at least partially carried within the pipe-carrying region.

Abstract: A pipe carrier in an embodiment includes a pipe-carrying region in which forward and rear pipe lifting assemblies are arranged to lift and carry a pipe section. For example, the pipe-carrying region lies rearwards of the front traveling support of the pipe carrier, and forwards of the rear traveling support of the pipe carrier. The pipe carrier includes a modular extension assembly carrying an energy source for powering the pipe carrier, wherein the energy source is at least partially carried within the pipe-carrying region.

Abstract: A computer-implemented method is described for detecting a change in one or more attributes associated with a consumer of financial services, and generating, based at least in part on the detected change, a prediction that the consumer of financial services is likely to initiate an action with regard to one or more financial accounts associated with the consumer.

Abstract: A non-traditional computing machine having no operands and no linear addressing of code or data is disclosed. A code space having multiple dimensions contains programmed instructions each having a unique position defined with respect to the code space dimensions. A data space having multiple dimensions contains data bits each having a unique position defined with respect to the data space dimensions. A code pointer has a position and a direction within the code space. The code pointer position identifies a present instruction. A data pointer has a position and a direction within the data space. The data pointer position identifies a present data bit. The programmed instructions are selected from an instruction set that includes instructions for navigating the code pointer to select instructions and navigating the data pointer to select data bits. The computing machine operates to manipulate the data in the data space according the programmed instructions.

Abstract: A non-traditional computing machine having no operands and no linear addressing of code or data is disclosed. A code space having multiple dimensions contains programmed instructions each having a unique position defined with respect to the code space dimensions. A data space having multiple dimensions contains data bits each having a unique position defined with respect to the data space dimensions. A code pointer has a position and a direction within the code space. The code pointer position identifies a present instruction. A data pointer has a position and a direction within the data space. The data pointer position identifies a present data bit. The programmed instructions are selected from an instruction set that includes instructions for navigating the code pointer to select instructions and navigating the data pointer to select data bits. The computing machine operates to manipulate the data in the data space according the programmed instructions.