Patents by Inventor David Craig McGowan

David Craig McGowan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bicyclic pyridazinones and methods of use thereof
    Patent number: 11858913
    Abstract: Disclosed herein are compounds of Formula I: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: January 2, 2024
    Assignee: Aligos Therapeutics, Inc.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • Modulators of THR-? and methods of use thereof
    Patent number: 11840532
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a patient with one or more of the above compounds.
    Type: Grant
    Filed: July 8, 2021
    Date of Patent: December 12, 2023
    Assignee: Aligos Therapeutics, Inc.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval
  • Oxindoles and methods of use thereof
    Patent number: 11793815
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: October 24, 2023
    Assignee: Aligos Therapeutics, Inc.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • 2-pyridones and methods of use thereof
    Patent number: 11786532
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Grant
    Filed: November 5, 2021
    Date of Patent: October 17, 2023
    Assignee: Aligos Therapeutics, Inc.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • BICYCLIC PYRIDAZINONES AND METHODS OF USE THEREOF
    Publication number: 20220144811
    Abstract: Disclosed herein are compounds of Formula I: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Application
    Filed: November 5, 2021
    Publication date: May 12, 2022
    Applicant: ALIGOS THERAPEUTICS, INC.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • 2-PYRIDONES AND METHODS OF USE THEREOF
    Publication number: 20220143032
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Application
    Filed: November 5, 2021
    Publication date: May 12, 2022
    Applicant: ALIGOS THERAPEUTICS, INC.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • OXINDOLES AND METHODS OF USE THEREOF
    Publication number: 20220143031
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a subject with one or more of the above compounds.
    Type: Application
    Filed: November 5, 2021
    Publication date: May 12, 2022
    Applicant: ALIGOS THERAPEUTICS, INC.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval, Leonid Beigelman
  • MODULATORS OF THR-BETA AND METHODS OF USE THEREOF
    Publication number: 20220009924
    Abstract: Disclosed herein are compounds of Formula I?: or a stereoisomer or a tautomer thereof, or a pharmaceutically acceptable salt thereof, pharmaceutical compositions comprising such compounds, and methods of treating disease by administering or contacting a patient with one or more of the above compounds.
    Type: Application
    Filed: July 8, 2021
    Publication date: January 13, 2022
    Applicant: ALIGOS THERAPEUTICS, INC.
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Koen Vandyck, Jerome Deval
  • Pyrrolo[3,2-d] pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 11220504
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: January 11, 2022
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Stefaan Julien Last, Serge Maria Aloysius Pieters, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Aryl substituted pyrimidines for use in influenza virus infection
    Patent number: 11117887
    Abstract: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
    Type: Grant
    Filed: April 3, 2020
    Date of Patent: September 14, 2021
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Tim Hugo Maria Jonckers, David Craig McGowan, Jérôme Émile Georges Guillemont, Werner Constant J Embrechts, Guillaume Jean Maurice Mercey, Christophe Francis Robert Nestor Buyck, Wendy Mia Albert Balemans, Pierre Jean-Marie Bernard Raboisson
  • Purine derivatives for the treatment of viral infections
    Patent number: 11104678
    Abstract: The present invention relates to purine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 6, 2019
    Date of Patent: August 31, 2021
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: Jean-François Bonfanti, Frédéric Marc Maurice Doublet, Werner Embrechts, Jérôme Michel Claude Fortin, David Craig McGowan, Pierre Jean-Marie Bernard Raboisson
  • Dihydropyranopyrimidines for the treatment of viral infections
    Patent number: 11053256
    Abstract: This invention relates to dihydropyranopynmidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: June 30, 2017
    Date of Patent: July 6, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, Jérôme Émile Georges Guillemont, David Craig McGowan, Werner Constant Johan Embrechts, Ludwig Paul Cooymans, Laurent Calmus
  • Pyrimidine prodrugs for the treatment of viral infections and further diseases
    Patent number: 10968184
    Abstract: This invention relates to pyrimidine prodrug derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
    Type: Grant
    Filed: September 28, 2017
    Date of Patent: April 6, 2021
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Jérôme Émile Georges Guillemont, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson, David Craig McGowan, Werner Constant Johan Embrechts, Bart Henri Theresia Stoops, Florence Marie Herschke, Jacques Armand Henri Bollekens, Laurent Jacques Emile Calmus
  • Pyridone derivatives for the treatment of viral infections and further diseases
    Patent number: 10865193
    Abstract: This invention relates to pyridone derivatives, processes for their preparation, pharmaceutical compositions, and their use in therapy.
    Type: Grant
    Filed: June 5, 2019
    Date of Patent: December 15, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson
  • Thieno[3,2-d]pyrimidines derivatives for the treatment of viral infections
    Patent number: 10822347
    Abstract: This invention relates to thieno[3,2-d]pyrimidines derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: May 7, 2019
    Date of Patent: November 3, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson
  • Pyrrolo [3,2-d]pyrimidine derivatives for the treatment of viral infections and other diseases
    Patent number: 10781216
    Abstract: This invention concerns pyrrolo[3,2-d]pyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treatment and/or therapy of diseases.
    Type: Grant
    Filed: June 14, 2019
    Date of Patent: September 22, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Serge Maria Aloysius Pieters, Stefaan Julien Last, Werner Embrechts, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • Heterocyclic substituted 2-amino quinazoline derivatives for the treatment of viral infections
    Patent number: 10723707
    Abstract: This invention relates to heterocyclic substituted 2-amino-quinazoline derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: April 8, 2019
    Date of Patent: July 28, 2020
    Assignee: Janssen Sciences Ireland Unlimited Company
    Inventors: Stefaan Julien Last, David Craig McGowan, Werner Embrechts, Serge Maria Aloysius Pieters, Tim Hugo Maria Jonckers, Pierre Jean-Marie Bernard Raboisson
  • 2-aminopyrimidine derivatives for the treatment of viral infections
    Patent number: 10647684
    Abstract: This invention relates to 2-aminopyrimidine derivatives, processes for their preparation, pharmaceutical compositions, and their use in treating viral infections.
    Type: Grant
    Filed: April 12, 2019
    Date of Patent: May 12, 2020
    Assignee: JANSSEN SCIENCES IRELAND UNLIMITED COMPANY
    Inventors: David Craig McGowan, Pierre Jean-Marie Bernard Raboisson, Tim Hugo Maria Jonckers
  • Heterocyclic indoles for use in influenza virus infection
    Patent number: 10626108
    Abstract: The current invention relates to a compound of formula (I) which can be used for the treatment of, or against viral influenza infections.
    Type: Grant
    Filed: November 25, 2016
    Date of Patent: April 21, 2020
    Assignee: JANSSEN SCIENCES IRELAND UC
    Inventors: Tim Hugo Maria Jonckers, David Craig McGowan, Jérôme Émile Georges Guilllemont, Ludwig Paul Cooymans, Werner Constant Johan Embrechts, Christophe Francis Robert Nestor Buyck, Wendy Mia Albert Balemans, Pierre Jean-Marie Bernard Raboisson
  • Aryl substituted pyrimidines for use in influenza virus infection
    Patent number: 10611755
    Abstract: The invention relates to compounds having the structure of formula (I) which can be used for the treatment of or against influenza infections.
    Type: Grant
    Filed: January 19, 2017
    Date of Patent: April 7, 2020
    Assignee: Janssen Sciences Ireland UC
    Inventors: Tim Hugo Maria Jonckers, David Craig McGowan, Jérôme Émile Georges Guillemont, Werner Constant J Embrechts, Guillaume Jean Maurice Mercey, Christophe Francis Robert Nestor Buyck, Wendy Mia Albert Balemans, Pierre Jean-Marie Bernard Raboisson