Abstract: Some aspects of this disclosure are directed to implementing hardware-based obfuscation of digital data. For example, some aspects of this disclosure relate to a method, including performing a capture operation that loads a plurality of primary input (PI) bits into corresponding shift registers of a plurality of test data registers (TDRs) disposed on one or more digital semiconductor devices and configured to store a plurality of secret information bits. The method further includes performing a sequence of shift operations on the plurality of TDRs to obtain a plurality of output bits. The method further includes applying, by an authenticating processor, a derivation function on the plurality of output bits to extract the plurality of secret information bits thereby authenticating the one or more digital semiconductor devices.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. The wound roll forms an upper axial end and a lower axial end. The wound roll is defined by a length extending between the upper axial end and the lower axial end. The cylindrical sleeve forms a distal end and a proximal end. The cylindrical sleeve is defined by a length extending between the distal end and the proximal end.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. The wound roll forms an upper axial end and a lower axial end. The wound roll is defined by a length extending between the upper axial end and the lower axial end. The cylindrical sleeve forms a distal end and a proximal end. The cylindrical sleeve is defined by a length extending between the distal end and the proximal end.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. The wound roll forms an upper axial end and a lower axial end. The wound roll is defined by a length extending between the upper axial end and the lower axial end. The cylindrical sleeve forms a distal end and a proximal end. The cylindrical sleeve is defined by a length extending between the distal end and the proximal end.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. At least a portion of the inner surface of the cylindrical sleeve is defined by a Sheffield Smoothness that is less than 350. A method is also disclosed.

Abstract: An apparatus includes first and second panels continuously joined along a first side edge, a second side edge and a bottom edge. A top portion of the respective first and second side panels defines an opening of the bag. A pair of hems each extend along the top portion of the bag. Drawstrings are enclosed within respective ones of the hems and short seals are provided to weld the first panel, the second panel, and respective ends of the drawstrings together. The short seals are each located proximate to respective ones of the side edges. A first reduced opening seal is provided to weld the first panel, the second panel, and the drawstrings together. The first reduced opening seal is located adjacent to the first side edge and includes a convex polygonal shape.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. The wound roll forms an upper axial end and a lower axial end. The wound roll is defined by a length extending between the upper axial end and the lower axial end. The cylindrical sleeve forms a distal end and a proximal end. The cylindrical sleeve is defined by a length extending between the distal end and the proximal end.

Abstract: An assembly is disclosed. The assembly includes a cylindrical sleeve and a length of material that is wound upon itself defining a wound roll. The cylindrical sleeve includes an inner surface and an outer surface. The inner surface of the cylindrical sleeve defines a passage extending through the cylindrical sleeve. The length of material includes an inner surface and an outer surface. A portion of the inner surface of the length of material forms a passage extending through the wound roll. The outer surface of the cylindrical sleeve is secured to the portion of the inner surface of the length of material that forms the passage extending through the wound roll. At least a portion of the inner surface of the cylindrical sleeve is defined by a Sheffield Smoothness that is less than 350. A method is also disclosed.

Abstract: An apparatus includes first and second panels continuously joined along a first side edge, a second side edge and a bottom edge. A top portion of the respective first and second side panels defines an opening of the bag. A pair of hems each extend along the top portion of the bag. Drawstrings are enclosed within respective ones of the hems and short seals are provided to weld the first panel, the second panel, and respective ends of the drawstrings together. The short seals are each located proximate to respective ones of the side edges. A first reduced opening seal is provided to weld the first panel, the second panel, and the drawstrings together. The first reduced opening seal is located adjacent to the first side edge and includes a convex polygonal shape.

Abstract: The invention concerns RAC-PK and fragments thereof, as well as activators and inhibitors of RAC-PK for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK for use in screening potential mimics or modulators thereof. A method for screening for agents capable of affecting the activity of GSK3 is also disclosed. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. There is also provided a process for activating RAC-PK comprising treatment thereof with a phosphatase inhibitor.

Abstract: The invention concerns RAC-PK and fragments thereof, as well as activators and inhibitors of RAC-PK for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK for use in screening potential mimics or modulators thereof. A method for screening for agents capable of affecting the activity of GSK3 is also disclosed. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. There is also provided a process for activating RAC-PK comprising treatment thereof with a phosphatase inhibitor.

Abstract: The present invention relates to a method and system for edge treatment of a film in which one or both edges of the film is heated to a temperature above a softening point of a DSC onset temperature. In one embodiment, the edges of film are heated to a temperature above the peak DSC temperature. A central portion of the film between the edges remains at a lower temperature. In one embodiment, an edge heat treatment apparatus having a heated channel is used to receive an edge portion of the film and heat the edge portion.

Abstract: The invention concerns RAC-PK and fragments thereof, as well as activators and inhibitors of RAC-PK for use as medicaments, particularly in the treatment of diseases concerned with abnormalities in processes modulated by insulin, such as cellular proliferation, insulin deficiency and/or excess blood sugar levels. Moreover, the invention provides RAC-PK for use in screening potential mimics or modulators thereof. A method for screening for agents capable of affecting the activity of GSK3 is also disclosed. The invention further provides a screening kit comprising the RAC-PK as an active principle, and a method for screening compounds which are candidate mimics or modulators of RAC-PK activity comprising detecting specific interactions between the candidate compounds and RAC-PK. There is also provided a process for activating RAC-PK comprising treatment thereof with a phosphatase inhibitor.

Abstract: Disclosed are crystallisable mutants of protein kinase B/Akt, crystals of these mutants, and X-ray coordinate data for the crystals. Methods of use of the coordinate data for identification of modulators of protein kinase activity and for structural analysis of other protein kinases are provided. Also provided are methods of activating protein kinases, in particular AGC kinases, using peptide or non-peptide mimetics of sequences from protein kinase B/Akt, or other AGC protein kinases such as PRK2.

Abstract: Disclosed are mutants of protein kinase B/Akt which can be crystallised in an enzymatically active conformation, crystals of these mutants and X-ray coordinate data for the crystals. Also disclosed are methods of using the coordinate data provided for identification of modulators of protein kinase activity and for structural analysis of other protein kinases, in particular AGC kinases.