Abstract: A method of detecting a flow in sequence of images of a material. Providing a sequence of at least three images of an area of the material. Each image includes a plurality of voxels or regions of interest such that the at least three images of the area of the material provide for each voxel or region of interest an intensity for at least three points in time, Fourier transforming for each voxel or region of interest to obtain a frequency distribution including the intensities for the at least three points in time, analysing for each voxel or region of interest and generating a processed image of area of the material including the voxels or regions of interest, associating voxels or regions of interest that have a larger amplitude at a higher frequency range with a first visual property and voxels or regions of interest that have smaller amplitude in the higher frequency range with a second visual property.

Abstract: A method of analyzing tissue includes inserting a radiation source into tissue, impinging radiation upon the tissue, obtaining a sample signal of the radiation that impinges upon the tissue, and determining a refractive index of the tissue from the sample signal. The method may also include determining at least one other optical property of the tissue. The method may provide for identifying tissue as part of a biopsy method. A device for analyzing tissue may include a low-coherence interferometer and a probe optically coupled to the interferometer, where the probe includes a radiation source.