Patents by Inventor David DeGoey

David DeGoey has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and Methods for Treating HCV Infection
    Publication number: 20190358214
    Abstract: The present invention features compositions and methods for the treatment of HCV infection. In one embodiment, the compositions of the invention comprise (1) Compound 1 or a pharmaceutically acceptable salt thereof, and (2) Compound 2a or a pharmaceutically acceptable salt thereof. In another embodiment, the compositions of the invention comprise (1) Compound 1 or a pharmaceutically acceptable salt thereof, and (2) a prodrug of Compound 2a (e.g., one of Compounds 2b-2k or Examples 3-1 to 3-10) or a pharmaceutically acceptable salt of said prodrug.
    Type: Application
    Filed: November 13, 2017
    Publication date: November 28, 2019
    Applicant: AbbVie Inc.
    Inventors: Brian Brown, Hui-Ju Chen, David DeGoey, Geoff Halvorsen, John Hartung, Howard R. Heyman, Nathan Ide, Dale Kempf, Allen C. Krueger, Tao Li, Tongmei Li, Steven R. Martinez, Christopher C. Marvin, John T. Randolph, Eric Voight, Rolf Wagner, Jaclyn Chau
  • (Indazol-4-yl) hexahydropyrrolopyrrolones and methods of use
    Patent number: 9682985
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein GAr, L1, Z1 and Z2 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav1.7 and/or Nav1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
    Type: Grant
    Filed: March 14, 2016
    Date of Patent: June 20, 2017
    Assignee: AbbVie Inc.
    Inventors: Jerome Daanen, David DeGoey, Jennifer M. Frost, Tammie Jinkerson, Steve Latshaw, Lei Shi
  • (Indazol-4-YL) Hexahydropyrrolopyrrolones and Methods of Use
    Publication number: 20160264582
    Abstract: Compounds of formula (I) and pharmaceutically acceptable salts, esters, amides, or radiolabelled forms thereof, wherein GAr, L1, Z1 and Z2 are as defined in the specification, are useful in treating conditions or disorders prevented by or ameliorated by voltage-gated sodium channels, e.g., Nav 1.7 and/or Nav 1.8. Methods for making the compounds are disclosed. Also disclosed are pharmaceutical compositions of compounds of formula (I), and methods for using such compounds and compositions.
    Type: Application
    Filed: March 14, 2016
    Publication date: September 15, 2016
    Applicant: AbbVie Inc.
    Inventors: Jerome Daanen, David DeGoey, Jennifer M. Frost, Tammie Jinkerson, Steve Latshaw, Lei Shi
  • Potassium channel modulators
    Patent number: 8859549
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein ring G1, R1, and R2 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Grant
    Filed: May 8, 2012
    Date of Patent: October 14, 2014
    Assignee: AbbVie, Inc.
    Inventors: Brian S. Brown, Tongmei Li, Sridhar Peddi, Arturo Perez-Medrano, David DeGoey
  • Potassium channel modulators
    Patent number: 8609674
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein G1, R2, R1a, R1b, X, X1, X2, X3, Rx, J, k, n, q, and t are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: December 17, 2013
    Assignee: AbbVie Inc.
    Inventors: Arturo Perez-Medrano, Sridhar Peddi, David DeGoey
  • Potassium channel modulators
    Patent number: 8609669
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein R1, R2, R3, R4, and R5 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: December 17, 2013
    Assignee: AbbVie Inc.
    Inventors: Xiangdong Xu, Jennifer Van Camp, Marc J. Scanio, William H. Bunnelle, Lei Shi, Augustine T. Osuma, David DeGoey, Arturo Perez-Medrano, Sridhar Peddi, Jyoti R. Patel
  • POTASSIUM CHANNEL MODULATORS
    Publication number: 20120289500
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein ring G1, R1, and R2 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Application
    Filed: May 8, 2012
    Publication date: November 15, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Brian S. Brown, Tongmei Li, Sridhar Peddi, Arturo Perez-Medrano, David DeGoey
  • Potassium Channel Modulators
    Publication number: 20120122890
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein G1, R2, R1a, R1b, X, X1, X2, X3, Rx, J, k, n, q, and t are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 17, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Arturo Perez-Medrano, Sridhar Peddi, David DeGoey
  • Potassium Channel Modulators
    Publication number: 20120122888
    Abstract: Disclosed herein are KCNQ potassium channels modulators of formula (I) wherein R1, R2, R3, R4, and R5 are as defined in the specification. Compositions comprising such compounds; and methods for treating conditions and disorders using such compounds and compositions are also described.
    Type: Application
    Filed: November 2, 2011
    Publication date: May 17, 2012
    Applicant: ABBOTT LABORATORIES
    Inventors: Xiangdong Xu, Jennifer Van Camp, Marc J. Scanio, William H. Bunnelle, Lei Shi, Augustine T. Osuma, David DeGoey, Arturo Perez-Medrano, Sridhar Peddi, Jyoti R. Patel
  • Prodrugs of HIV protease inhibitors
    Publication number: 20070270383
    Abstract: A compound of the formula is disclosed as a prodrug of an HIV protease inhibitor. Methods and compositions for inhibiting HIV protease activity and treating HIV infection are also disclosed.
    Type: Application
    Filed: June 29, 2005
    Publication date: November 22, 2007
    Inventors: David DeGoey, William Flosi, David Grampovnik, Larry Klein, Dale Kempf, Xiu Wang
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20070232627
    Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
    Type: Application
    Filed: December 20, 2006
    Publication date: October 4, 2007
    Inventors: David Betebenner, David DeGoey, Clarence Maring, Allan Krueger, Nobuhiko Iwasaki, Todd Rockway, Curt Cooper, David Anderson, Pamela Donner, Brian Green, Dale Kempf, Dachun Liu, Keith McDaniel, Darold Madigan, Christopher Motter, John Pratt, Jason Shanley, Michael Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami Pilot-Matias, Sherie Masse, Robert Carrick, Wenping He, Liangjun Lu, David Grampovnik
  • ANTI-VIRAL COMPOUNDS
    Publication number: 20070197558
    Abstract: Compounds effective in inhibiting replication of Hepatitis C virus (“HCV”) or other viruses are disclosed. This invention is also directed to compositions comprising such compounds, co-formulation or co-administration of such compounds with other anti-viral or therapeutic agents, processes and intermediates for the syntheses of such compounds, and methods of using such compounds for the treatment of HCV or other viral infections.
    Type: Application
    Filed: December 20, 2006
    Publication date: August 23, 2007
    Inventors: David Betebenner, David DeGoey, Clarence Maring, Allan Krueger, Nobuhiko Iwasaki, Todd Rockway, Curt Cooper, David Anderson, Pamela Donner, Brian Green, Dale Kempf, Dachun Liu, Keith McDaniel, Darold Madigan, Christopher Motter, John Pratt, Jason Shanley, Michael Tufano, Rolf Wagner, Rong Zhang, Akhteruzzaman Molla, Hongmei Mo, Tami Pilot-Matias, Sherie Masse, Robert Carrick, Wenping He, Liangjun Lu, David Grampovnik
  • HIV protease inhibiting compounds
    Publication number: 20050159469
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 10, 2004
    Publication date: July 21, 2005
    Inventors: John Randolph, Hui-Ju Chen, David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Peggy Huang, Douglas Hutchinson, Dale Kempf, Larry Klein, Ming Yeung
  • HIV protease inhibiting compounds
    Publication number: 20050148623
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 9, 2004
    Publication date: July 7, 2005
    Inventors: David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Dale Kempf, Larry Klein, Ming Yeung, John Randolph, Xiu Wang, Su Yu
  • HIV protease inhibiting compounds
    Publication number: 20050131042
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 11, 2003
    Publication date: June 16, 2005
    Inventors: Charles Flentge, Hui-Ju Chen, David DeGoey, William Flosi, David Grampovnik, Peggy Huang, Dale Kempf, Larry Klein, Allan Krueger, Darold Madigan, John Randolph, Minghua Sun, Ming Yeung, Chen Zhao
  • HIV protease inhibiting compounds
    Publication number: 20050131017
    Abstract: A compound of the formula is disclosed as an HIV protease inhibitor. Methods and compositions for inhibiting an HIV infection are also disclosed.
    Type: Application
    Filed: December 11, 2003
    Publication date: June 16, 2005
    Inventors: David DeGoey, Charles Flentge, William Flosi, David Grampovnik, Dale Kempf, Larry Klein