Abstract: The present invention provides compositions and methods for simultaneously detecting mutational status and gene copy number. In particular, the present invention provides simultaneous measurement of gene copy number and detection of the L858R and Exon 19 del mutations in a tissue sample.

Abstract: The present invention provides compositions and methods for simultaneously detecting mutational status and gene copy number. In particular, the present invention provides simultaneous measurement of gene copy number and detection of the L858R and Exon 19 del mutations in a tissue sample.

Abstract: The invention relates to chemical compounds of formula (I): or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.

Abstract: The invention relates to chemical compounds of formula IA or IB: or pharmaceutically acceptable salts thereof which possess CSF-1R kinase inhibitory activity and are accordingly useful for their anti-cancer activity and thus in methods of treatment of the human or animal body. The invention also relates to processes for the manufacture of said chemical compounds, to pharmaceutical compositions containing them and to their use in the manufacture of medicaments of use in the production of an anti-cancer effect in a warm-blooded animal such as man.

Abstract: The gazebo structure is made of four aluminum columns that support a roof made of aluminum, stainless steal, and trans-lucid acrylic resistant to ultraviolet rays.

Abstract: A rail that requires minimum force to slide an object. It can be assemble by rail pieces until obtaining the desired length.

Abstract: A moveable gazebo structure that slides over the pool to cover it. The gazebo is mounted on a platform that rolls on rails installed adjacent to the pool. The gazebo may slide from north to south and vice-versa or from east to west or vice-versa. This invention is motorized but it may be moved manually.

Abstract: An apparatus for drying resinous material includes a reaction vessel and a pair of counter-rotating hollow shafts disposed in the vessel. Each of the shafts supports a plurality of blades for stirring the resinous material to be dried in the vessel. A flow of hot gas is continuously supplied through hollow shafts into the blades and released into a reaction vessel through a plurality of apertures in the blades when the blades are in contact with the resinous material.

Abstract: A reactor apparatus is provided with an outer jacket surrounding the reaction vessel. The jacket is formed by a plurality of baffles having triangular cross-section. At least some of the baffles are provided with adjustable deflectors. Heat exchanging fluid is admitted into the space between the jacket and the vessel outer wall. The triangular cross-section of the baffles and adjustable deflectors allow optimum regulation of reaction conditions, for example reaction temperature and in effect increase reactor productivity.