Abstract: Embodiments of the present disclosure generally relate to methods for forming a waveguide. Methods may include measuring a waveguide substrate, the waveguide having a substrate thickness distribution; and depositing an index-matched layer onto a surface of the waveguide, the index-matched layer having a first surface disposed on the waveguide substrate and a second surface opposing the first surface, wherein the index-matched layer is disposed only over a portion of the waveguide substrate, and a device slope of a second surface of the index-matched layer is substantially the same as the waveguide slope of the first surface of the waveguide.

Abstract: Provided are methods of sensitizing LKB1/STK11 deficient cancers to immune therapy. A method for treatment for LKB1/STK11 deficient cancers is provided comprising administration of inhibitor or inhibitors of one or more of NAMPT, CD38, SHP2, CXCR1/2, HDAC4 and PARP in combination with immunotherapy.

Abstract: The present disclosure relates to various solid-state forms of N-hydroxy 2-{6-[(6-fluoro-quinolin-2-ylmethyl)-amino]-3-aza-bicyclo[3.1.0]hex-3-yl}pyrimidine-5-carboxamide and methods of making the same. Such forms of N-hydroxy 2-{6-[(6-fluoro-quinolin-2-ylmethyl)-amino]-3-aza-bicyclo[3.1.

Abstract: The invention relates to methods and compositions for detecting colorectal cancer and colorectal polyps by measurement of metabolites in bodily fluids such as urine, including diacetylspermine and kynurenine.

Abstract: Disclosed herein are methods and systems for creating or providing a blockchain-based digital stable token, facilitating user identification, fund transfer, and payments and trading. The systems and methods provided herein may comprise providing a stable token, a non-stable token, reward rate for payment in the stable token, interest rate for holding the stable token, wherein zero inflation and deflation of the stable token against a weighted average price, such as the PCE price index, can be achieved by constantly optimizing one or more of the i) the reward rate, ii) the interest rate, and iii) the trading between the non-stable token and stable token through a Linear-Quadratic-Gaussian controller.

Abstract: Disclosed herein are methods and systems for facilitating payment comprising the exchange of digital tokens from consumer accounts to merchant accounts in exchange for goods and/or services wherein the merchant may request the issuance of reward tokens, backed up by a central entity, to the consumer accounts. The reward tokens can then be used to facilitate payment for goods or services from the requesting merchant.

Abstract: A closet has the ability to dehumidify, heat and/or circulate the air therein in order to dry clothes. The dehumidification and circulation functions may be (1) included in a unitary closet structure, usable indoor or outdoor, (2) included as a modular unit for retro-fitting into an existing closet storage solution, or (3) a chassis that may be scaled and built into closets during their design and manufacture. The closet can include a sanitizing unit and may move air through a condenser, warm the dehumidified air, and deliver that treated air to a different portion of the closet, creating an air flow about the clothes hanging therein. A condensate collection unit may automatically shut down the system when a condensate reservoir is filled, thereby preventing condensate overflow. The closet may operate without the heat and/or dehumidification function, where external air may be circulated in and out of the closet.

Abstract: A heating assembly can include a switching valve which can include certain pressure sensitive features. These features can be configured to change from a first position to a second position based on a pressure of a fuel. The valve can be used with either a first fuel or a second fuel different from the first. The valve can become locked or be held in either the first or the second position. For example, a set fuel pressure can cause the valve to move to a closed position and the valve can become locked or held in that position. If the pressure decreases, the valve can remain in the locked position. Actuation of a reset switch can allow the valve to move to a new position, such as an open position.

Abstract: A heater assembly can be used with a gas appliance. The gas appliance can be a dual fuel appliance for use with one of a first fuel type or a second fuel type different than the first. The heater assembly can include a pressure sensor and a plurality of valves operable by a control module dependent upon a detected fuel pressure. The valves may be solenoid valves that can reduce the available fuel delivery paths to limit fuel delivery to a burner when a higher pressure, such as detection of LP gas, is detected.

Abstract: A heating assembly can include a locking valve with a reset switch which can include certain pressure sensitive features. These features can be configured to change from a first position to a second position based on a pressure of a fuel. The valve can be used with either a first fuel or a second fuel different from the first. The valve can become locked or be held in either the first or the second position. For example, a set fuel pressure can cause the valve to move to a closed position and the valve can become locked or held in that position. If the pressure decreases, the valve can remain in the locked position. Actuation of the reset switch can allow the valve to move to a new position, such as an open position. The locking valve can be linked to additional valves to lock them in position as well.

Abstract: A heater assembly can be used with a gas appliance. The gas appliance can be a dual fuel appliance for use with one of a first fuel type or a second fuel type different than the first. The heater assembly can include a housing, and an actuation member. The housing has a first fuel hook-up for connecting the first fuel type to the heater assembly, a second fuel hook-up for connecting the second fuel type to the heater assembly, and an internal valve. The actuation member can control the position of the internal valve based on whether the first or the second fuel hook-up is used.

Abstract: A heating system can include certain pressure sensitive features. These features can be configured to change from a first position to a second position based on a pressure of a fuel flowing into the feature. These features can include, fuel selector valves, pressure regulators, burner nozzles, and oxygen depletion sensor nozzles, among other features.

Abstract: A dual fuel heating system can be used in a gas appliance. A dual fuel heating system can have a fuel selector valve for selecting between a first fuel and a second fuel different from the first. The dual fuel heating system can include a regulator unit configured to regulate the pressure of the two different fuels. The selector valve determines which flow path for which fuel is open and which is closed.

Abstract: A dual fuel heating source can have a burner and a nozzle. The heating source can be configured to use one of two different fuels flowing at different pressures. The nozzle can have a body, the body defining an outlet opening, an inlet, and an inner chamber. The nozzle can be configured for the first fuel in a first position of said nozzle, and can be configured for a second fuel in a second position.

Abstract: An additive heat transfer unit (AHTU) can be part of or added to an air source heat pump HVAC system. The heat pump system can include a compressor, an expansion valve, first and second air source heat exchangers, and a reversing valve. The system can have a cooling mode and a heating mode, such that in the cooling mode the first air source heat exchanger functions as an evaporator and the second air source heat exchanger functions as a condenser, this being reversed in the heating mode. The AHTU can include a liquid source heat exchanger that can be used to increase the efficiency of the system.

Abstract: A heater assembly can be used with a gas appliance. The gas appliance can be a dual fuel appliance for use with one of a first fuel type or a second fuel type different than the first. The heater assembly can include at least one pressure regulator, a housing, and an actuation member. The housing has a first fuel hook-up for connecting the first fuel type to the heater assembly, a second fuel hook-up for connecting the second fuel type to the heater assembly, and an internal valve. The actuation member can control the position of the internal valve based on whether the first or the second fuel hook-up is used.

Abstract: A heating assembly can include a gas hook-up and a pressure switch. The pressure switch can be in fluid communication with the gas hook-up and be movable at a predetermined threshold pressure from a first position to a second position. The pressure switch can be further configured such that if a fuel is connected to the gas hook-up that has a delivery pressure either above the predetermined threshold pressure in one situation or below the predetermined threshold pressure in another, the fuel will act on the pressure switch to move it from the first position to the second position.

Abstract: A heating system can include certain pressure sensitive features. These features can be configured to change from a first position to a second position based on a pressure of a fuel flowing into the feature. These features can include, fuel selector valves, pressure regulators, burner nozzles, and oxygen depletion sensor nozzles, among other features.

Abstract: A heater can be configured to operate with either a first fuel at a first pressure or a second fuel at a second pressure. In some embodiments, a pressure regulator unit is configured to regulate the pressure of either the first fuel or the second fuel and to direct either the first fuel or the second fuel towards a combustion chamber. A nozzle assembly can be configured to inject the fuel into the combustion chamber.

Abstract: A heating assembly can be used with one of a first fuel type or a second fuel type different than the first. The heating assembly can include a housing have a first actuation member and a second actuation member. The first and second actuation members can be positioned within respective first and second fuel hook-ups. The first and second actuation members can be configured such that connecting a fuel source to the heater assembly moves one of the actuation members from a first position to a second position to control flow through the heating assembly.