Abstract: An organosilicon compound with carbinol groups is prepared. A catalyzed hydrogenation process for combining an aldehyde-functional organosilicon compound with hydrogen produces the carbinol-functional organosilicon compound.

Abstract: An organosilicon compound with carboxy-functional groups is prepared. An oxidation process in which an aldehyde-functional organosilicon compound and an oxygen source are combined produces the carboxy-functional organosilicon compound.

Abstract: An organosilicon compound with a primary amino-functional group is prepared. A catalyzed reductive amination process for combining a secondary imine-functional organosilicon compound with ammonia and hydrogen produces the primary amino-functional organosilicon compound.

Abstract: An organosilicon compound with a primary aminopropyl-functional group is prepared. A catalyzed reductive amination process for combining a secondary propylimine-functional organosilicon compound with ammonia and hydrogen produces the primary aminopropyl-functional organosilicon compound.

Abstract: A polyolefin-polydiorganosiloxane block copolymer may be prepared by Piers-Rubinsztajn reaction.

Abstract: A catalyzed hydroformylation process of an alkenyl-functional organosilicon compound with carbon monoxide and hydrogen produces an aldehyde-functional organosilicon compound.

Abstract: A composition includes a silyl hydride (having at least one silicon-bonded hydrogen atom per molecule) and a fluorinated triarylborane Lewis acid. In the method, the Lewis acid catalyzes reaction of silicon bonded hydrogen atoms from the silyl hydride and water, thereby forming a siloxane bond in the resulting product. The composition and method can be used to form siloxane intermediates and cured networks.

Abstract: A polyolefin-polydiorganosiloxane block copolymer may be prepared by hydrosilylation reaction.

Abstract: A polyolefin-polydiorganosiloxane block copolymer may be prepared by hydrosilylation reaction.

Abstract: A polyolefin-polydiorganosiloxane block copolymer may be prepared by Piers-Rubinsztajn reaction.

Abstract: The present disclosure provides a composition. In an embodiment, a composition is provided and comprises a Compound 1 shown below: For Compound 1, R1 through R24 are the same or different. R1 through R24 each is independently selected from the group consisting of hydrogen, unsubstituted hydrocarbyl, substituted hydrocarbyl, cyano, alkoxy, aryloxy, and NR?2. R? is hydrogen or hydrocarbyl; wherein two or more of adjacent R1 to R24 may optionally form one or more ring structures. The Component Z is selected from the group consisting Group Z-1, Group Z-2, Group Z-3, Group Z-4, Group Z-5, Group Z-6 and Group Z-7 shown below: For Compound 1, one or more hydrogen atoms may optionally be substituted with deuterium.

Abstract: Provided is a composition comprising a compound selected from Structure 1, as described herein:

Abstract: The present disclosure provides a composition. In an embodiment, a composition is provided and comprises a Compound 1 shown below: For Compound 1, R1 through R24 are the same or different. R1 through R24 each is independently selected from the group consisting of hydrogen, unsubstituted hydrocarbyl, substituted hydrocarbyl, cyano, alkoxy, aryloxy, and NR?2. R? is hydrogen or hydrocarbyl; wherein two or more of adjacent R1 to R24 may optionally form one or more ring structures. The Component Z is selected from the group consisting Group Z-1, Group Z-2, Group Z-3, Group Z-4, Group Z-5, Group Z-6 and Group Z-7 shown below: For Compound 1, one or more hydrogen atoms may optionally be substituted with deuterium.

Abstract: Provided is a composition comprising a compound selected from Structure 1, as described herein:

Abstract: Graft copolymer polyelectrolyte complexes are disclosed for the efficient delivery of anionic, cationic or polyelectrolyte therapeutic agents into biological cells, and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such complexes comprise (1) an anionic graft copolymer containing an anionic polymer backbone, with pendent carboxylic acid groups and pendant chains containing amphipathic or hydrophilic polymers covalently bonded to a portion of the pendant carboxylic acid groups, (2) one or more anionic, cationic or polyelectrolyte therapeutic agents, and (3) optionally a liposome optionally containing an additional therapeutic agent. Also disclosed are functional nanoparticles containing the complexes.

Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.

Abstract: Graft copolymer polyelectrolyte complexes are disclosed for the efficient delivery of anionic, cationic or polyelectrolyte therapeutic agents into biological cells, and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such complexes comprise (1) an anionic graft copolymer containing an anionic polymer backbone, with pendent carboxylic acid groups and pendant chains containing amphipathic or hydrophilic polymers covalently bonded to a portion of the pendant carboxylic acid groups, (2) one or more anionic, cationic or polyelectrolyte therapeutic agents, and (3) optionally a liposome optionally containing an additional therapeutic agent. Also disclosed are functional nanoparticles containing the complexes.

Abstract: Graft copolymer polyelectrolyte complexes are disclosed for the efficient delivery of anionic, cationic or polyelectrolyte therapeutic agents into biological cells, and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such complexes comprise (1) an anionic graft copolymer containing an anionic polymer backbone, with pendent carboxylic acid groups and pendant chains containing amphipathic or hydrophilic polymers covalently bonded to a portion of the pendant carboxylic acid groups, (2) one or more anionic, cationic or polyelectrolyte therapeutic agents, and (3) optionally a liposome optionally containing an additional therapeutic agent. Also disclosed are functional nanoparticles containing the complexes.

Abstract: Innovative graft polymers designed for the efficient delivery of antisense molecules into biological cells and for maintaining the biological activity of these molecules while in serum and other aqueous environments are provided. Such polymers may comprise an anionic graft polymer comprising an anionic polymer backbone with pendant carboxylic acid groups and pendant chains comprising amphipathic or hydrophilic polymers covalently bonded to a portion of said pendant carboxylic acid groups. Antisense molecule delivery vectors comprising such polymers in combination with cationic agents for delivery of antisense molecules are also disclosed.

Abstract: Biocompatible, biodegradable copolymer-xerogel nanocomposites contain a biodegradable, biocompatible copolymer, silica nanoparticles and one or more therapeutic agents, that are useful for wound dressings, medical devices and drug delivery applications.