Abstract: Methods for the treatment of textiles used for facial masks assure for the inactivation of viruses captured by the textile. The aerosol droplets are absorbed by the textile, and any viruses in the water droplets react with a virucidal substance. The surface of textile fibers is first exposed to gaseous plasma to assure appropriate wettability. The textile is then soaked in a diluted water solution of a virucidal substance. The excessive water solution is optionally removed by draining, and the drained textile is then dried. The methods enable uniform coating of the textile fibers with an extremely thin film of virucidal substance. A typical concentration of the virucidal substance in the textiles treated according to the methods of the aspects of disclosed embodiments is about 10 g/kg. Such a small concentration is benign to humans but effectively inactivates the viruses that might be captured by the textile.

Abstract: An energy-efficient disinfection or sterilisation of contaminated liquid, such as water contaminated with viruses or microbes includes an asymmetric configuration of a cavitation nozzle made from dielectric material that enables the formation of a single, stable cavitation bubble of a large volume. A low-pressure gaseous plasma is continuously formed inside the cavitation bubble by electrodes to prevent contact of the metallic electrode with liquid water and Ohmic heating of the contaminated water. The electrodes are connected to a high voltage power supply. The power supply enables formation of a continuous stable gaseous discharge inside the cavitation bubble and radicals and radiation useful for destruction of viruses to the levels below the current US EPA standard in few minutes, while the temperature of liquid water remains practically unchanged. Use is not only for hospitals and pharmaceutical companies but the food industry and agriculture as well.

Abstract: The present disclosure provides improved methods for purifying recombinant protein, vaccine and gene therapy preparations, such as vectors in a suspension, as well as new means to better assay residual nucleic acids in a composition comprising genetically engineered particles. One aspect of the present disclosure is a method for purifying a liquid composition comprising genetically engineered particles from nucleic acid impurities comprising the steps of (i) adding a Dps protein to the suspension comprising genetically engineered particles, (ii) precipitating a complex comprising the nucleic acid impurities and the Dps protein and (iii) removing the precipitated complex comprising the nucleic acid impurities and Dps protein from the suspension comprising genetically engineered particles. Another aspect of the disclosure is a method to assay nucleic acid impurities in a liquid composition comprising genetically engineered particles or a pharmaceutical composition comprising genetically engineered particles.

Abstract: An energy-efficient disinfection or sterilisation of contaminated liquid, such as water contaminated with viruses or microbes includes an asymmetric configuration of a cavitation nozzle made from dielectric material that enables the formation of a single, stable cavitation bubble of a large volume. A low-pressure gaseous plasma is continuously formed inside the cavitation bubble by electrodes to prevent contact of the metallic electrode with liquid water and Ohmic heating of the contaminated water. The electrodes are connected to a high voltage power supply. The power supply enables formation of a continuous stable gaseous discharge inside the cavitation bubble and radicals and radiation useful for destruction of viruses to the levels below the current US EPA standard in few minutes, while the temperature of liquid water remains practically unchanged. Use is not only for hospitals and pharmaceutical companies but the food industry and agriculture as well.