Patents by Inventor David Dodman

David Dodman has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process for the preparation of aryl hydrazone and aryl hydrazine
    Patent number: 7138548
    Abstract: A process for the preparation of a compound of formula (I): wherein Ar represents an optionally substituted aromatic carbocycle or heterocycle, and R1 and R2 independently represent hydrogen, C1-10 alkyl, C(O)C1-10 alkyl or optionally substituted aryl provided that R1 and R2 are not both hydrogen which process comprises reacting together a compound of formula (II): Ar—X??(II) wherein Ar is as defined in relation to formula (I) and X represents a leaving group with a a compound of formula (III) wherein R1 and R2 are as defined in relation to formula (I) under aqueous conditions in the presence of a Pd (II) salt, a ligand and a Group I or Group II metal hydroxide base at a pH greater than 7. Compounds of formula (I) may be hydrolysed to the corresponding hydrazine.
    Type: Grant
    Filed: October 2, 2002
    Date of Patent: November 21, 2006
    Assignee: Avecia Limited
    Inventors: Andrew John Blacker, David Dodman, David Anthony Jackson, Jan Michael Fielden, John Heathcote Atherton
  • Process for the preparation of aryl hydrazone and aryl hydrazine
    Publication number: 20050124824
    Abstract: A process for the preparation of a compound of formula (I): wherein Ar represents an optionally substituted aromatic carbocycle or heterocycle, and R1 and R2 independently represent hydrogen, C1-10alkyl, C(O)C1-10alkyl or optionally substituted aryl provided that R1 and R2 are not both hydrogen which process comprises reacting together a compound of formula (II): Ar—X??(II) wherein Ar is as defined in relation to formula (I) and X represents a leaving group with a a compound of formula (III) wherein R1 and R2 are as defined in relation to formula (I) under aqueous conditions in the presence of a Pd (II) salt, a ligand and a Group I or Group II metal hydroxide base at a pH greater than 7. Compounds of formula (I) may be hydrolysed to the corresponding hydrazine.
    Type: Application
    Filed: October 2, 2002
    Publication date: June 9, 2005
    Inventors: Andrew Blacker, David Dodman, David Jackson, Jan Fielden, John Atherton