Patents by Inventor David Douda

David Douda has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MULTIVALENT AND BISPECIFIC ANTIBODY CONSTRUCTS AND METHODS OF USE THEREOF
    Publication number: 20260242471
    Abstract: The present disclosure relates to multivalent, e.g., trivalent, and bispecific antibody constructs capable of binding an antigen on a cytotoxic effector cell and a tumor-associated antigen (TAA) on a tumor cell. Pharmaceutical compositions comprising such antibody constructs and methods of preparing and using such constructs and compositions, e.g., for the treatment of cancer, are also disclosed.
    Type: Application
    Filed: April 16, 2025
    Publication date: August 20, 2026
    Inventors: Nicole AFACAN, Chayne L. Piscitelli, Thomas Spreter Von Kreudenstein, Patricia Zwierzchowski, Nina E. Weisser, David DOUDA, Kara White-Moyes, Harsh Pratap
  • TRIVALENT AND TRISPECIFIC ANTIBODY CONSTRUCTS AND METHODS OF USE THEREOF
    Publication number: 20260028403
    Abstract: The present disclosure provides trivalent and trispecific antibody constructs capable of binding two different antigens on one or more cytotoxic effector cell(s) and a tumor-associated antigen (TAA) on a tumor cell. Pharmaceutical compositions comprising such antibody constructs and methods of preparing and using such constructs and compositions, e.g., for the treatment of cancer, are also disclosed.
    Type: Application
    Filed: April 15, 2025
    Publication date: January 29, 2026
    Inventors: Nicole Afacan, Chayne L. Piscitelli, Lisa Newhook, Purva Prashant Bhojane, Patricia Zwierzchowski, Peter Repenning, Nina E. Weisser, Thomas Spreter Von Kreudenstein, Paula Tao, David Douda, Kelsey Ferns, Sylwia Jancowski, Sukhbir Singh Kang, Lee Freiburger, Nichole K. Escalante
  • MULTIVALENT AND BISPECIFIC ANTIBODY CONSTRUCTS AND METHODS OF USE THEREOF
    Publication number: 20240327516
    Abstract: The present disclosure relates to multivalent, e.g., trivalent, and bispecific antibody constructs capable of binding an antigen on a cytotoxic effector cell and a tumor-associated antigen (TAA) on a tumor cell. Pharmaceutical compositions comprising such antibody constructs and methods of preparing and using such constructs and compositions, e.g., for the treatment of cancer, are also disclosed.
    Type: Application
    Filed: June 18, 2024
    Publication date: October 3, 2024
    Inventors: Nicole AFACAN, Chayne L. PISCITELLI, Thomas SPRETER VON KREUDENSTEIN, Patricia ZWIERZCHOWSKI, Nina E. WEISSER, David DOUDA, Kara WHITE-MOYES, Harsh PRATAP
  • MASKED IL12 FUSION PROTEINS AND METHODS OF USE THEREOF
    Publication number: 20230122079
    Abstract: The present disclosure relates to masked IL12 fusion proteins, compositions comprising the same and methods of using the compositions for the treatment of a variety of diseases including cancer.
    Type: Application
    Filed: March 23, 2021
    Publication date: April 20, 2023
    Inventors: Ryan Blackler, Gesa Volkers, David Douda, Thomas Spreter Von Kreudenstein, Genevieve Desjardins, Nicole Afacan