Abstract: A core, rotatably fitted within a body of a manifold assembly, includes a flow channel configured so that, when the core is rotated 360 degrees, fluid communication between ports of the body is only established by the channel at a first position, between first and second ports, and at a second position, between third and fourth ports. The channel may define an angle greater than 90 degrees and less than 180 degrees, preferably 120 degrees; and, the rotation, between first and second positions, may be approximately 180 degrees. In a medical injection system, the first and second ports are fill ports of the assembly, the first being coupled to a reservoir, and the second being coupled to a pump; and the third and fourth ports are injection ports of the assembly, the third being coupled to the pump, and the fourth being coupled to an injection line.

Abstract: A core, rotatably fitted within a body of a manifold assembly, includes a flow channel configured so that, when the core is rotated 360 degrees, fluid communication between ports of the body is only established by the channel at a first position, between first and second ports, and at a second position, between third and fourth ports. The channel may define an angle greater than 90 degrees and less than 180 degrees, preferably 120 degrees; and, the rotation, between first and second positions, may be approximately 180 degrees. In a medical injection system, the first and second ports are fill ports of the assembly, the first being coupled to a reservoir, and the second being coupled to a pump; and the third and fourth ports are injection ports of the assembly, the third being coupled to the pump, and the fourth being coupled to an injection line.