Patents by Inventor David E. Honigs

David E. Honigs has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6477392
    Abstract: In a method to improve the calibration of a non-invasive, near infrared (NIR) measurement device, a plurality of data terms is formed for the NIR measurement device. Then the codependence of the data terms is evaluated by forming cross-products terms using the data terms. Next, sets of prespecified sizes are randomly formed from the data terms and the cross-product terms. Each of these sets of terms is evaluated by testing the ability of the set to predict a set of accurate measurements using regression analysis. The method then selects one of the sets based on preselected criteria and uses the selected set to calibrate the NIR measurement device.
    Type: Grant
    Filed: July 14, 2000
    Date of Patent: November 5, 2002
    Assignee: Futrex Inc.
    Inventors: David E. Honigs, Robert D. Rosenthal
  • Patent number: 6151517
    Abstract: A method and apparatus for performing quantitative noninvasive measurement of blood analytes, includes correction for measurement interference caused by pulse beat and changing body chemistry associated with blood circulation through the part of the body being measured as a function of time. A hypoglycemia monitor and alarm is provided which takes advantage of the methods described for separating pulse beat information from the measurement signals.
    Type: Grant
    Filed: January 22, 1999
    Date of Patent: November 21, 2000
    Assignee: Futrex Inc.
    Inventors: David E. Honigs, Robert D. Rosenthal
  • Patent number: 5545376
    Abstract: In the system for analyzing aqueous samples, the aqueous sample is deposited upon a sheet of filter paper which is held in a filter holder by clamping the peripheral edges of the filter paper between male and female threaded members of the filter holder. The filter paper with the sample is dried by a heated air stream directed perpendicularly toward the paper so that it flows around and through the paper. After the sample has been dried, it is analyzed by near infrared spectral analysis to measure the constituents of the dried sample.
    Type: Grant
    Filed: August 1, 1990
    Date of Patent: August 13, 1996
    Assignee: Perstorp Analytical, Inc.
    Inventors: David E. Honigs, Donald Lynch
  • Patent number: 5251006
    Abstract: In a spectrophotometer having an oscillating grating, an automatic calibration system is provided to ensure that the instrument constants are recomputed before each measurement of an unknown sample. In the system, whenever a reference scan is carried out, a second scan through an absorbance standard is carried out automatically and the data obtained is used to correct the instrument coefficients relating the angular position of the grating to the wavelength. The corrected coefficients are then stored to be used in the measurement of the unknown sample immediately thereafter. For near infrared spectrum measurements, the absorbance standard is a polystyrene plate. For visual measurements, the absorbance standard is a didymium plate. The didymium plate is mounted on the polystyrene plates eclipse a portion of the polystyrene plate.
    Type: Grant
    Filed: March 7, 1991
    Date of Patent: October 5, 1993
    Assignee: NIRSystems Incorporated
    Inventors: David E. Honigs, Timothy G. Kelly
  • Patent number: 5055684
    Abstract: An improved near infrared spectrophotometer is disclosed which reduces wave shift errors arising from hot spots in a light source. A ground quartz plate uniformly diffuses radiation from the light source to evenly illuminate the entrance slit for a diffraction grating. Radiation emerges from the entrance slit with a uniform angular intensity distribution and is dispersed into a spectrum by a reflecting diffraction grating towards an exit slit. A narrow wavelength band of radiation passes through the exit slit to illuminate a sample. Because the entrance slit is uniformly illuminated, without regard to variations in radiation intensity due to hot spots in the source, wave shift errors in the reflectivity measurements for the sample are reduced.
    Type: Grant
    Filed: December 6, 1989
    Date of Patent: October 8, 1991
    Assignee: NIRSystems Incorporated
    Inventor: David E. Honigs
  • Patent number: 4847066
    Abstract: A method is described for treating consumable products, such as foods, drugs or dietary supplements, for example drugs enclosed in capsules, to detect contamination. A colorimetric indicator, which can react with a contaminating substance such as cyanide, is incorporated into the consumable product or the packaging for the product. When the indicator comes in contact with the contaminating substance, a readily detectable color signal is produced.
    Type: Grant
    Filed: February 2, 1987
    Date of Patent: July 11, 1989
    Assignee: Board of Regents of the University of Washington
    Inventors: David E. Honigs, Jonathan H. Perkins, Bradley J. Tenge
  • Patent number: 4800279
    Abstract: Methods are disclosed for quantifying physical properties of gaseous, liquid or solid samples. The near-infrared absorbance spectra of a representative field of calibration samples are measured and recorded using a spectrophotometer. The absorbance spectra of the calibration samples are evaluated by a row-reduction algorithm to determine which wavelengths in the near-infrared spectrum, and associated weighting constants, are statistically correlated to the physical property being quantified. The near-infrared absorbance of actual samples is then measured at each of the correlated wavelengths, and then corrected by the corresponding weighting constants. A reference value for the physical property being quantified is then computed from the corrected measure of the absorbance of the sample at each of the correlated wavelengths.
    Type: Grant
    Filed: September 13, 1985
    Date of Patent: January 24, 1989
    Assignee: Indiana University Foundation
    Inventors: Gary M. Hieftje, David E. Honigs, Thomas B. Hirschfeld
  • Patent number: 4746616
    Abstract: A method is described for treating consumable products, such as foods, drugs or dietary supplements, for example drugs enclosed in capsules, to detect contamination. A colorimetric indicator, which can react with a contaminating substance such as cyanide, is incorporated into the consumable product or the packaging for the product. When the indicator comes in contact with the contaminating substance, a readily detectable color signal is produced.
    Type: Grant
    Filed: July 16, 1988
    Date of Patent: May 24, 1988
    Assignee: The Board of Regents of the University of Washington
    Inventors: David E. Honigs, Jonathan H. Perkins, Bradley J. Tenge