Patents by Inventor David E. Junker
David E. Junker has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 7892561Abstract: The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.Type: GrantFiled: August 4, 2009Date of Patent: February 22, 2011Assignee: Schering-Plough Animal Health CorporationInventors: David E. Junker, Mark D. Cochran
-
Publication number: 20090311282Abstract: The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.Type: ApplicationFiled: August 4, 2009Publication date: December 17, 2009Inventors: DAVID E. JUNKER, MARK D. COCHRAN
-
Patent number: 7585648Abstract: The invention provides new, specific nucleic acids encoding antigenic peptides from the protein GDF8. The invention also provides nucleic acids encoding fusion proteins comprising the new peptides, immunogens and vaccines based on the nucleic acids encoding new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.Type: GrantFiled: April 2, 2008Date of Patent: September 8, 2009Assignee: Schering-Plough Animal Health CorporationInventors: David E. Junker, Mark D. Cochran
-
Publication number: 20090208522Abstract: The invention provides a fusion protein comprising a plant virus coat protein and a GDF8 peptide domain, or antigenic fragment of the GDF8 peptide domain. Plant virus vectors expressing the fusion protein and methods of using these vectors are also provided.Type: ApplicationFiled: August 22, 2008Publication date: August 20, 2009Inventors: David E. Junker, Mark D. Cochran, Mark L. Smith, Kenneth E. Palmer, Gregory P. Pogue
-
Patent number: 7432079Abstract: The invention provides a fusion protein comprising a plant virus coat protein and a GDF8 peptide domain, or antigenic fragment of the GDF8 peptide domain. Plant virus vectors expressing the fusion protein and methods of using these vectors are also provided.Type: GrantFiled: December 21, 2005Date of Patent: October 7, 2008Assignee: Schering-Plough Animal Health CorporationInventors: David E. Junker, Mark D. Cochran, Mark L. Smith, Kenneth E. Palmer, Gregory P. Pogue
-
Publication number: 20080227156Abstract: The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.Type: ApplicationFiled: April 2, 2008Publication date: September 18, 2008Inventors: David E. Junker, Mark D. Cochran
-
Patent number: 7371726Abstract: The invention provides new, specific antigenic peptides from the protein GDF8. The invention also provides fusion proteins comprising the new peptides, immunogens and vaccines based on the new peptides and/or fusion proteins, antibodies that specifically bind to the new peptides of GDF8, and methods of treating animals in order to modulate the activity of GDF8, employing vaccines or antibodies according to the invention.Type: GrantFiled: December 21, 2004Date of Patent: May 13, 2008Assignee: Schering-Plough Animal Health CorporationInventors: David E. Junker, Mark D. Cochran
-
Patent number: 6497882Abstract: This invention provides a recombinant swinepox virus comprising a foreign DNA sequence inserted into the swinepox virus genomic DNA, wherein the foreign DNA sequence is inserted within a HindIII K fragment of the swinepox virus genomic DNA and is capable of being expressed in a swinepox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: December 24, 2002Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6328975Abstract: This invention provides a recombinant swinepox virus comprising a foreign DNA sequence which is (a) inserted into the swinepox virus genomic DNA, wherein the foreign DNA sequence is inserted within a region of the genome which corresponds to the 2.0 kb HindIII to BglII subfragment located within the HindIII M fragment of the swinepox virus genome and (b) is expressed in a swinepox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: January 19, 1995Date of Patent: December 11, 2001Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6299882Abstract: The present invention provides methods and reagents for inducing active immunity in animals. In particular, the present invention provides recombinant herpesviruses having foreign DNA that are capable of inducing immunity to the herpesvirus and/or the source of the foreign DNA. The present invention also provides mutant herpesviruses having portions of their genome deleted. Preferably, foreign DNA is introduced, or portions of the genome are deleted, in the UL54.5 open reading frame of avian herpesviruses or the UL43 open reading frame of Marek's disease virus.Type: GrantFiled: April 9, 1999Date of Patent: October 9, 2001Assignee: Schering CorporationInventor: David E. Junker
-
Patent number: 6294176Abstract: The present invention provides a recombinant raccoonpox virus comprising a raccoonpox virus viral genome which contains a foreign DNA sequence inserted into a non-essential region within the HindIII “U” genomic region, the HindIII “M” genomic region, or HindIII “N” genomic region of the raccoonpox virus genome. The present invention provides a recombinant raccoonpox virus comprising a raccoonpox virus viral genome which contains a deletion in a raccoonpox virus host range gene of the viral genome. The present invention provides a homology vector for producing a recombinant raccoonpox virus by inserting a foreign DNA sequence into the raccoonpox virus genome. The present invention provides a recombinant raccoonpox virus which is useful as a vaccine in mammalian and avian species.Type: GrantFiled: July 10, 1998Date of Patent: September 25, 2001Assignee: Schering-Plough Veterinary Corp.Inventors: Mark D. Cochran, David E. Junker
-
Patent number: 6251403Abstract: This invention provides a recombinant swinepox virus comprising a foreign DNA sequence inserted into the swinepox virus genomic DNA, wherein the foreign DNA sequence is inserted within a HindIII M fragment of the swinepox virus genomic DNA and is capable of being expressed in a swinepox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: June 26, 2001Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6221361Abstract: This invention provides a recombinant swinepox virus comprising a foreign DNA inserted into a swinepox virus genomic DNA, wherein the foreign DNA is inserted into an EcoRI site within the approximately 3.2 Kb subfragment of the HindIII K fragment of the swinepox virus genomic DNA and is capable of being expressed in a swinepox virus infected host cell. The invention further provides a recombinant swinepox virus designated S-SPV-120, S-SPV-121, S-SPV-122, S-SPV-127, and S-SPV-128. The invention further provides vaccines and methods of immunization of the recombinant swinepox virus.Type: GrantFiled: July 25, 1996Date of Patent: April 24, 2001Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6136318Abstract: This invention provides a recombinant fowlpox virus comprising a foreign DNA sequence inserted into the fowlpox virus genomic DNA, wherein the foreign DNA sequence is inserted within a 3.5 kB EcoRI fragment of the fowlpox virus genomic DNA and is capable of being expressed in a fowlpox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: October 24, 2000Inventors: Mark D. Cochran, David E. Junker
-
Patent number: 6127163Abstract: The present invention relates to a recombinant swinepox virus capable of replication comprising foreign DNA inserted into a site in the swinepox viral DNA which is not essential for replication of the swinepox virus.Type: GrantFiled: January 19, 1996Date of Patent: October 3, 2000Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6123949Abstract: The present invention provides a recombinant fowlpox virus designated S-FPV-043 (ATCC Accession No. VR 2395). A vaccine useful for immunizing an animal against fowlpox virus and Newcastle disease virus is provided which comprises an effective immunizing amount of S-FPV-043 and a suitable carrier. A method of immunizing an animal against fowlpox virus and Newcastle disease virus is also provided which comprises administering to the animal an effective immunizing dose of the vaccine.Type: GrantFiled: June 7, 1995Date of Patent: September 26, 2000Inventors: Mark D. Cochran, David E. Junker
-
Patent number: 6033904Abstract: This invention provides a recombinant swinepox virus comprising a foreign DNA sequence inserted into the swinepox virus genomic DNA, wherein the foreign DNA sequence is inserted within a HindIII N fragment of the swinepox virus genomic DNA and is capable of being expressed in a swinepox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: March 7, 2000Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 6001369Abstract: This invention provides a recombinant fowlpox virus comprising a foreign DNA sequence inserted into the fowlpox virus genomic DNA, wherein the foreign DNA sequence is inserted within a 4.2 kB EcoRI fragment of the fowlpox virus genomic DNA and is capable of being expressed in a fowlpox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: December 14, 1999Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker
-
Patent number: 5965138Abstract: This invention provides a recombinant herpesvirus of turkeys comprising a herpesvirus of turkeys viral genome which contains a foreign DNA sequence inserted within the EcoR1 #9 fragment of the herpesvirus of turkeys viral genome, and the foreign DNA sequence is capable of being expressed in a host cell infected with the herpesvirus of turkeys.This invention provides a recombinant herpesvirus of turkeys-Marek's disease virus chimera comprising a herpesvirus of turkeys unique long viral genome region and a Marek's disease virus unique short region.Lastly, this invention provides homology vectors for producing a recombinant herpesvirus of turkeys, host cells, and vaccines and methods for immunization.Type: GrantFiled: December 22, 1994Date of Patent: October 12, 1999Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker, Martha A. Wild, Phillip A. Singer
-
Patent number: 5925358Abstract: This invention provides a recombinant fowlpox virus comprising a foreign DNA sequence inserted into the fowlpox virus genomic DNA, wherein the foreign DNA sequence is inserted within a 2.8 kB EcoRI fragment of the fowlpox virus genomic DNA and is capable of being expressed in a fowlpox virus infected host cell. The invention further provides homology vectors, vaccines and methods of immunization.Type: GrantFiled: June 7, 1995Date of Patent: July 20, 1999Assignee: Syntro CorporationInventors: Mark D. Cochran, David E. Junker