Abstract: This invention relates to the treatment of chronic kidney disease, including diabetic nephropathy, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, non-diabetic chronic kidney disease, renal fibrosis or acute kidney injury by the administration of an RGD mimetic integrin receptor antagonist, either as a single agent or in combination with other agents.

Abstract: Use of a GPR119 agonist in the prevention or treatment of hypoglycemia is disclosed, addition, pharmaceutical compositions and combinations of a GPR1 19 agonist with insulin, insulin analog, insulin secretagogue or or other drug(s) that reduces plasma glucose levels to below 70 mg/dL described herein.

Abstract: This invention relates to the treatment of chronic kidney disease, including diabetic nephropathy, focal segmental glomerulosclerosis (FSGS), nephrotic syndrome, non-diabetic chronic kidney disease, renal fibrosis or acute kidney injury by the administration of an RGD mimetic integrin receptor antagonist, either as a single agent or in combination with other agents.

Abstract: Methods for identifying drug-saccharide conjugates that bind the mannose receptor, C type 1, (MRC1) and may be taken up by cells expressing MRC1, and the use of such drug-saccharide conjugates for treatment of particular diseases are described. In particular, the methods for identifying insulin-saccharide conjugates that bind the MRC1 receptor and may be taken up by cells expressing the MRC1 and use of such conjugates for treatment of diabetes are described.

Abstract: Methods for identifying drug-saccharide conjugates that bind the mannose receptor, C type 1, (MRC1) and may be taken up by cells expressing MRC1, and the use of such drug-saccharide conjugates for treatment of particular diseases are described. In particular, the methods for identifying insulin-saccharide conjugates that bind the MRC1 receptor and may be taken up by cells expressing the MRC1 and use of such conjugates for treatment of diabetes are described.

Abstract: Systems and methods improve the equitable distribution the processing capacity of a computing device processing work items retrieved from multiple queues in a workflow system. A retrieval priority is determined for each of the plurality of queues and work items are retrieved from each of the multiple queues according to the retrieval priority. The retrieved work items are then stored in a central data structure. Multiple processing components process the work items stored in the central data structure. The number of processing components is selectively adjusted to maximize efficiency.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods automatically generate a model of a form or other document and identify the form or other document. In one aspect, a system and method normalize an image of a document and identify the relative positions of vertical and horizontal lines in the normalized image. The relative positions of vertical and horizontal lines of the normalized image are the model of the document image. The model may be stored in a record, such as an array. The system and method compare the relative positions of vertical and horizontal lines of the model to the relative positions of vertical and horizontal lines of other models to identify a matching model.

Abstract: Systems and methods automatically generate a model of a form or other document and identify the form or other document. In one aspect, a system and method normalize an image of a document and identify the relative positions of the vertical and horizontal lines in the normalized image. The relative positions of the vertical and horizontal lines of the normalized image are the model of the document image. The model may be stored in a record, such as an array. The system and method compare the relative positions of the horizontal and vertical lines of the model to the relative positions of horizontal and vertical lines of other models to identify a matching model.

Abstract: Systems and methods automatically generate a model of a form or other document and identify the form or other document. In one aspect, a system and method normalize an image of a document and identify the relative positions of vertical and horizontal lines in the normalized image. The relative positions of vertical and horizontal lines of the normalized image are the model of the document image. The model may be stored in a record, such as an array. The system and method compare the relative positions of vertical and horizontal lines of the model to the relative positions of vertical and horizontal lines of other models to identify a matching model.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods automatically generate a model of a form or other document and identify the form or other document. In one aspect, a system and method normalize an image of a document and identify the relative positions of vertical and horizontal lines in the normalized image. The relative positions of vertical and horizontal lines of the normalized image are the model of the document image. The model may be stored in a record, such as an array. The system and method compare the relative positions of vertical and horizontal lines of the model to the relative positions of vertical and horizontal lines of other models to identify a matching model.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods automatically generate a model of a form or other document and identify the form or other document. In one aspect, a system and method normalize an image of a document and identify the relative positions of vertical and horizontal lines in the normalized image. The relative positions of vertical and horizontal lines of the normalized image are the model of the document image. The model may be stored in a record, such as an array. The system and method compare the relative positions of vertical and horizontal lines of the model to the relative positions of vertical and horizontal lines of other models to identify a matching model.

Abstract: Systems and methods improve the equitable distribution the processing capacity of a computing device processing work items retrieved from multiple queues in a workflow system. A retrieval priority is determined for each of the plurality of queues and work items are retrieved from each of the multiple queues according to the retrieval priority. The retrieved work items are then stored in a central data structure. Multiple processing components process the work items stored in the central data structure. The number of processing components is selectively adjusted to maximize efficiency.

Abstract: Systems and methods improve the equitable distribution the processing capacity of a computing device processing work items retrieved from multiple queues in a workflow system. A retrieval priority is determined for each of the plurality of queues and work items are retrieved from each of the multiple queues according to the retrieval priority. The retrieved work items are then stored in a central data structure. Multiple processing components process the work items stored in the central data structure. The number of processing components is selectively adjusted to maximize efficiency.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.

Abstract: Systems and methods analyze the physical structure of text rows in a document image, including the positions of one or more alignments of one or more character blocks in one or more text rows of the document image. The systems and methods determine one or more groups of text rows that are placed into a class based on the structures of the text rows, such as the positions of the one or more alignments of the one or more character blocks in each text row.