Patents by Inventor David E. Minnikin

David E. Minnikin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Use of monomycolyl glycerol (MMG) as an adjuvant
    Patent number: 8563009
    Abstract: Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators of human DC's we demonstrate their use in the development of a new generation of adjuvants suitable for human administration. We furthermore identify a number of highly active synthetic MMG analogues with great potential in cancer treatment, and for vaccine adjuvants against both infectious disease and disorders like Alzheimers disease.
    Type: Grant
    Filed: June 26, 2008
    Date of Patent: October 22, 2013
    Assignee: Statens Serum Institut
    Inventors: Else Marie Agger, Claire Andersen, Peter Andersen, Gurdyal S. Besra, David E. Minnikin
  • THE USE OF MONOMYCOLYL GLYCEROL (MMG) AS AN ADJUVANT
    Publication number: 20100310585
    Abstract: Here we identify MMG and its alpha- and ketomycolic acid derivatives as highly bioactive lipids derived from M. bovis BCG (Copenhagen) capable of stimulating and activating human DC's at exceedingly low doses. In addition to their direct role as immunostimulators of human DC's we demonstrate their use in the development of a new generation of adjuvants suitable for human administration. We furthermore identify a number of highly active synthetic MMG analogues with great potential in cancer treatment, and for vaccine adjuvants against both infectious disease and disorders like Alzheimers disease.
    Type: Application
    Filed: June 26, 2008
    Publication date: December 9, 2010
    Applicant: Statens Serum Institut
    Inventors: Else Marie Agger, Claire Andersen, Peter Andersen, Gurdyal S. Besra, David E. Minnikin