Patents by Inventor David E. Modrak

David E. Modrak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Sphingomyelin therapy of autoimmune disease
    Patent number: 7683044
    Abstract: Autoimmune disease therapy in a patient treated with apoptosis-inducing agents is enhanced by co-administration of sphingomyelin. The combination most likely enhances an autoimmune disease cell's ability to undergo ceramide-induced apoptosis by increasing the levels of sphingomyelin in all cellular compartments, thereby providing sufficient substrate for activated sphingomyelinase. In alternative embodiments, sphingomyelin may be administered alone, in combination with corticosteroids, and/or in combination with a apoptosis-inducing agent.
    Type: Grant
    Filed: September 18, 2007
    Date of Patent: March 23, 2010
    Assignee: Center for Molecular Medicine and Immunology
    Inventors: David E. Modrak, David M. Goldenberg