Patents by Inventor David E. NADIG

David E. NADIG has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases
    Patent number: 10231932
    Abstract: Processes of preparing pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of administering, and kits thereof are disclosed.
    Type: Grant
    Filed: October 31, 2014
    Date of Patent: March 19, 2019
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: Kelly Ann Swinney, Patricia Nell Hurter, David E. Nadig, David Smith, Vance Hayden Thomas, Martin Paul Warman
  • PROCESS OF PREPARING PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF CFTR MEDIATED DISEASES
    Publication number: 20160354316
    Abstract: Processes of preparing pharmaceutical compositions comprising 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid (Compound 1) in Form I and a solid dispersion comprising substantially amorphous N-(5-hydroxy-2,4-ditert-butyl-phenyl)-4-oxo-1H-quinoline-3-carboxamide (Compound 2), methods of treating, lessening the severity of or symptomatically treating CFTR mediated diseases, such as cystic fibrosis, methods of administering, and kits thereof are disclosed.
    Type: Application
    Filed: October 31, 2014
    Publication date: December 8, 2016
    Applicant: VERTEX PHARMACEUTICALS INCORPORATED
    Inventors: Kelly Ann SWINNEY, Patricia Nell HUNTER, David E. NADIG, David SMITH, Vance Hayden THOMAS, Martin Paul WARMAN