Abstract: Provided herein are tetracyclic heterocyclic compounds which can be useful for methods of treating a disease or for increasing neural plasticity. The compounds can also be useful for increasing dendritic spine density.

Abstract: Provided herein are methods for preparing intermediate amide compounds for the preparation of ergoline analogs.

Abstract: Provided herein are ibogaine compounds which can be useful for methods of treating a neuropsychiatric disease or neurological disorder, for increasing neural plasticity, or for modulating the function of a serotonin transporter.

Abstract: The present invention provides a method of using non-hallucinogenic analogs of psychedelic compounds for increasing neural plasticity of the neuronal cell, and a method of using thereof for treating a brain disorder.

Abstract: The present invention provides a method of using non-hallucinogenic analogs of psychedelic compounds for increasing neural plasticity of the neuronal cell, and a method of using thereof for treating a brain disorder.

Abstract: The present invention provides azepino-indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides R-3,4-methylenedioxy-N,N-dimethylamphetamine, and salts thereof, for treating brain disorders.

Abstract: Provided herein are psychoplastogens which can be useful for treating hearing loss.

Abstract: Provided herein are tetracyclic heterocyclic compounds which can be useful for methods of treating a disease or for increasing neural plasticity. The compounds can also be useful for increasing dendritic spine density.

Abstract: Provided herein are ergoline-derived heterocyclic compounds which can be useful for methods of treating a disease or for increasing neural plasticity. The compounds can also be useful for increasing dendritic spine density.

Abstract: Disclosed herein are compounds, compositions, and methods for promoting neuronal growth and/or improving neuronal structure with the compounds and compositions disclosed herein. Also described are methods of treating diseases or disorders that are mediated by the loss of synaptic connectivity and/or plasticity, such as neurological diseases and disorders, with non-hallucinogenic psychoplastogens.

Abstract: The present invention provides azepino-indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides substituted 1,2,3,4,5,6-hexahydroazepino[4,5-b]indoles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides N-substituted indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides N-substituted indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides N-substituted indoles and other heterocycles and methods of using the compounds for treating brain disorders.

Abstract: The present invention provides a method of using non-hallucinogenic analogs of psychedelic compounds for increasing neural plasticity of the neuronal cell, and a method of using thereof for treating a brain disorder.

Abstract: The present invention relates a composite insulation and shielding article and a method of permanently installing the composite article onto a system to provide at least radioactive shielding. The composite shielding for permanently reducing radioactive radiation emanating from a system comprises at least one inner layer, at least one outer layer, and a shielding layer between said inner and outer layers, said shielding layer comprising a shield material that reduces said radioactive radiation.

Abstract: An intelligent asynchronous controller (IAC) for use in operably coupling a plurality of asynchronous input/output (I/O) devices to a host central processing unit (CPU) is disclosed. The IAC is designed and programmed to control the transfer of data between the plurality of I/O devices and the CPU, to perform character processing on the data received from the I/O devices before transmission to the host CPU and to perform other types of data processing.

Abstract: A system for measuring and displaying the side and top profiles of an underwater pipeline as the pipeline is being laid on the sea floor by a pipe laying vessel. The profiles are determined by sequentially measuring the position of points spaced apart along the pipeline with respect to a point on the vessel. The measurements are accomplished by sequentially transmitting an acoustic signal from three, non-colinear transducers. The acoustic signals from each transmission is detected by a plurality of receivers spaced apart along the pipeline. As each receiver detects a transmission it produces an indicating signal on a pair of electrical conductors which are connected to the vessel and all of the receivers on the pipeline. The elapsed time between a transmission from a given transducer and detection of that transmission by each receiver is an indication of the distance between the transducer and each receiver.