Abstract: Aspects of the subject disclosure may include, for example, receiving employee performance data for a group of employees including a particular employee, the employee performance data including particular performance data for the particular employee, the employee performance data associated with key performance indicator (KPIs) for the group of employees including a particular KPI associated with the a task performed by the particular employee; determining, for a plurality of training courses, a probability of each training course being associated with improved performance by the group of employees for each KPI of the KPIs; producing a probability distribution and a confidence score, recommending, based on the probability distribution, one or more recommended training courses for the employee; exploring, based on the confidence score, training courses of the plurality of training courses having a relatively low confidence score; receiving subsequent performance data for a time period following completion of t

Abstract: A method and apparatus for identifying a plurality of users of a service of a network service provider as users known to each other are disclosed. For example, the method implemented via a processor obtains location information of a plurality of users of a service of a network service provider, selects a subset of users from the plurality of users that are deemed to be stationary, generates a score for each particular pair of users selected from the subset of users, determines for each particular pair of users, whether the score that is generated is greater than or equal to a threshold, identifies the pair of users as users who know each other, when the score for the particular pair of users is greater than or equal to the threshold, and performs an analysis to provide an offer to the pair of users, wherein the offer is based on the pair of users being identified as users who know each other.

Abstract: An apparatus, method, and system for changing or removal of a LED driver, a PCB or the lens after installation with one person, and minimal equipment and time and with ease of maintenance without removing the main support structure of the light fixture from a support structure.

Abstract: A method and apparatus for identifying a plurality of users of a service of a network service provider as users known to each other are disclosed. For example, the method implemented via a processor obtains location information of a plurality of users of a service of a network service provider, selects a subset of users from the plurality of users that are deemed to be stationary, generates a score for each particular pair of users selected from the subset of users, determines for each particular pair of users, whether the score that is generated is greater than or equal to a threshold, identifies the pair of users as users who know each other, when the score for the particular pair of users is greater than or equal to the threshold, and performs an analysis to provide an offer to the pair of users, wherein the offer is based on the pair of users being identified as users who know each other.

Abstract: A lighted emitting pole anchored to the ground. The bottom housing is bolted or anchored to an embedded support. The upper housing contains the light portion of the pole. The upper housing is constructed of an inner welded aluminum construction with optical film and an opaque acrylic tube or light guide. A fist donut shaped LED board with optics is mounted to a top of the upper housing and a second LED board with optics is mounted to a bottom of the upper housing. The LEDs emit light between the optical film and the light guide, which provides for an evenly distributed light throughout the pole. A cap is affixed to the top of the upper housing to protect the interior of the pole from the elements.

Abstract: An apparatus, method, and system for changing or removal of a LED driver, a PCB or the lens after installation with one person, and minimal equipment and time and with ease of maintenance without removing the main support structure of the light fixture from a support structure.

Abstract: The specification and drawing figures describe and show an edge illuminable wayfinder that includes a an illuminable graphic sandwich operatively connectable to a sealed light-emitting diode platform that are enclosed in a housing.

Abstract: The problem of how to select out of a large chemically accessible universe molecules representative of the diversity of that universe is resolved by the discovery of a method to validate molecular structural descriptors. Using the validated descriptors, optimally diverse subsets can be selected. In addition, from the universe, molecules with characteristics similar to a selected molecule can be identified. The validated descriptors also enable the generation of a huge virtual library of potential product molecules which could be formed by combinatorial arrangement of structural variations and cores. In this virtual library it is possible to search billions of possible product compounds in relatively short time frames.

Abstract: The use for biological screening purposes of a subset (library) of a large combinatorially accessible chemical universe increases the efficiency of the screening process only if the subset contains members representative of the total diversity of the universe. In order to insure inclusion in the subset of molecules representing the total diversity of the universe under consideration, valid molecular descriptors which quantitatively reflect the diversity of the molecules in the universe are required. A unique validation method is used to examine both a new three dimensional steric metric and some prior art metrics. With this method, the relative usefulness/validity of individual metrics can be ascertained from their application to randomly selected literature data sets.

Abstract: The distribution of chemical compounds in high-dimensional molecular descriptor space can be viewed in two dimensions by applying the projection method of this invention. This method has particular usefulness for viewing the relationships of a large number of compounds such as found in a large scale HTS or virtual combinatorial library. After selecting a representative subset of the larger data set of compounds, initially components from the high-dimensional descriptor space are determined by PCA. In order to relax an NLM projection using the PCA components as a start, the stress function is modified to reflect a local horizon beyound which the separation of the compounds is not meaningfully measureable. The resulting two dimensional projections provide a clear insight into the distribution of the chemical compounds in the higher dimensional space.

Abstract: The use for biological screening purposes of a subset (library) of a large combinatorially accessible chemical universe increases the efficiency of the screening process only if the subset contains members representative of the total diversity of the universe. In order to insure inclusion in the subset of molecules representing the total diversity of the universe under consideration, valid molecular descriptors which quantitatively reflect the diversity of the molecules in the universe are required. A unique validation method is used to examine both a new three dimensional steric metric and some prior art metrics. With this method, the relative usefulness/validity of individual metrics can be ascertained from their application to randomly selected literature data sets.

Abstract: The distribution of chemical compounds in high-dimensional molecular descriptor space can be viewed in two dimensions by applying the projection method of this invention. This method has particular usefulness for viewing the relationships of a large number of compounds such as found in a large scale HTS or virtual combinatorial library. After selecting a representative subset of the larger data set of comounds, initially components from the high-dimensional descriptor space are determined by PCA. In order to relax an NLM projection using the PCA components as a start, the stress function is modified to reflect a local horizon beyound which the separation of the compounds is not meaningfully measureable. The resulting two dimensional projections provide a clear insight into the distribution of the chemical compounds in the higher dimensional space.

Abstract: The use for biological screening purposes of a subset (library) of a large combinatorially accessible chemical universe increases the efficiency of the screening process only if the subset contains members representative of the total diversity of the universe. In order to insure inclusion in the subset of molecules representing the total diversity of the universe under consideration, valid molecular descriptors which quantitatively reflect the diversity of the molecules in the universe are required. A unique validation method is used to examine both a new three dimensional steric metric and some prior art metrics. With this method, the relative usefulness/validity of individual metrics can be ascertained from their application to randomly selected literature data sets.

Abstract: The use for biological screening purposes of a subset (library) of a large combinatorially accessible chemical universe increases the efficiency of the screening process only if the subset contains members representative of the total diversity of the universe. In order to insure inclusion in the subset of molecules representing the total diversity of the universe under consideration, valid molecular descriptors which quantitatively reflect the diversity of the molecules in the universe are required. A unique validation method is used to examine both a new three dimensional steric metric and some prior art metrics. With this method, the relative usefulness/validity of individual metrics can be ascertained from their application to randomly selected literature data sets.

Abstract: The problem of how to select out of a large chemically accessible universe molecules representative of the diversity of that universe is resolved by the discovery of a method to validate molecular structural descriptors. Using the validated descriptors, optimally diverse subsets can be selected. In addition, from the universe, molecules with characteristics similar to a selected molecule can be identified. The validated descriptors also enable the generation of a huge virtual library of potential product molecules which could be formed by combinatorial arrangement of structural variations and cores. In this virtual library it is possible to search billions of possible product compounds in relatively short time frames.

Abstract: The problem of how to select out of a large chemically accessible universe molecules representative of the diversity of that universe is resolved by the discovery of a method to validate molecular structural descriptors. Using the validated descriptors, optimally diverse subsets can be selected. In addition, from the universe, molecules with characteristics similar to a selected molecule can be identified. The validated descriptors also enable the generation of a huge virtual library of potential product molecules which could be formed by combinatorial arrangement of structural variations and cores. In this virtual library it is possible to search billions of possible product compounds in relatively short time frames.

Abstract: The problem of how to select out of a large chemically accessible universe molecules representative of the diversity of that universe is resolved by the discovery of a method to validate molecular structural descriptors. Using the validated descriptors, optimally diverse subsets can be selected. In addition, from the universe, molecules with characteristics similar to a selected molecule can be identified. The validated descriptors also enable the generation of a huge virtual library of potential product molecules which could be formed by combinatorial arrangement of structural variations and cores. In this virtual library it is possible to search billions of possible product compounds in relatively short time frames.

Abstract: The use of biological screening purposes of a subset (library) of a large combinatorially accessible chemical universe increases the efficiency of the screening process only if the subset contains members representative of the total diversity of the universe. In order to insure inclusion in the subset of molecules representing the total diversity of the universe under consideration, valid molecular descriptors which quantitatively reflect the diversity of the molecules in the universe are required. A unique validation method is used to examine both a new three dimensional steric metric and some prior art metrics. With this method, the relative usefulness/validity of individual metrics can be ascertained from their application to randomly selected literature data sets.

Abstract: An intermittent gas-lift apparatus and process of lifting liquids is described. The apparatus includes a chamber on the downhole end of a production tubing in communication with a sidestring tube. The sidestring tube is in communication with the high pressure gas stored within the casing above and below a packer. A valve in the sidestring permits the entrance of a lifting gas into the chamber to lift the liquids flowing therein to the surface. A surface bleed-down system minimizes the pressure in the production tubing. This increases the pressure differential between the formation and the interior of the casing and lifting chamber during the operation of the apparatus. The apparatus and process are suitable for use in many types of wells including wells of great depth and also those containing long hydrocarbon producing zones and/or deviated wells.