Abstract: The invention relates to a method of determining prefocused pulses with sufficiently low power and short duration to allow multi-slice in-vivo spectroscopic imaging of humans. The method has two main stages, analytic and numerical. In the analytic stage a magnetization response is selected with certain desired characteristics such as prefocused time. During the numerical stage, the response is then transformed into an RF pulse for use in magnetic resonance imaging. The theoretical response to the RF pulse is evaluated and characteristics such as duration and amplitude may be altered to meet further requirements. The theoretical response is then transformed into an RF pulse for use in magnetic resonance imaging or for further application of the numerical stage.