Patents by Inventor David E. Trentham

David E. Trentham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of treating rheumatoid arthritis with low dose type II collagen
    Patent number: 5856446
    Abstract: A method for suppressing autoimmune response in an afflicted joint in a human. The method involves oral administration of between about 5 and 25 .mu.g per day of type II collagen.
    Type: Grant
    Filed: July 5, 1996
    Date of Patent: January 5, 1999
    Assignee: Autoimmune Inc.
    Inventors: Howard L. Weiner, David A. Hafler, David E. Trentham
  • Method of treating rheumatoid arthritis with type II collagen
    Patent number: 5843445
    Abstract: The present invention is directed to a method and pharmaceutical formulations for the treatment of autoimmune arthritis and animal models therefore in mammals, including humans, by the oral, enteral or by-inhalation administration of whole collagen protein or biologically active peptide fragments of collagen.
    Type: Grant
    Filed: September 21, 1993
    Date of Patent: December 1, 1998
    Assignee: AutoImmune, Inc.
    Inventors: Howard L. Weiner, David E. Trentham
  • Method of treating rheumatoid arthritis with type collagen peptide fragments containing repeating sequences
    Patent number: 5783188
    Abstract: The present invention is directed to a method and pharmaceutical formulations for the treatment of autoimmune arthritis and animal models therefore in mammals, including humans, by the oral, enteral or by-inhalation administration of whole collagen protein or biologically active peptide fragments of collagen.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: July 21, 1998
    Assignee: AutoImmune, Inc.
    Inventors: Howard L. Weiner, David E. Trentham, David A. Hafler
  • Method of treating rheumatoid arthritis with soluble collagen
    Patent number: 5720955
    Abstract: The present invention is directed to a method and pharmaceutical formulations for the treatment of autoimmune arthritis and animal models therefore in mammals, including humans, by the oral, enteral or by-inhalation administration of whole collagen protein or biologically active peptide fragments of collagen.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: February 24, 1998
    Assignee: AutoImmune, Inc.
    Inventors: Howard L. Weiner, David E. Trentham, David A. Hafler
  • Method of treating rheumatoid arthritis with type II collagen
    Patent number: 5399347
    Abstract: The present invention is directed to a method and pharmaceutical formulations for the treatment of autoimmune arthritis and animal models therefore in mammals, including humans, by the oral, enteral or by-inhalation administration of whole collagen protein or biologically active peptide fragments of collagen.
    Type: Grant
    Filed: September 25, 1992
    Date of Patent: March 21, 1995
    Assignee: Autoimmune, Inc.
    Inventors: David E. Trentham, Howard L. Weiner, David A. Hafler