Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.

Abstract: An aerosol-generating system is provided, including: an aerosol-generating device including a heater element; and an aerosol-generating article configured to engage with the aerosol-generating device and including a medicament source; a volatile delivery enhancing compound source; at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source; and at least one piercing element disposed on a wall of the aerosol-generating article, the medicament source and the volatile delivery enhancing compound source being moveable relative to the at least one piercing element, and the at least one piercing element being configured to pierce the at least one frangible barrier when activated by a user.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device. The aerosol-generating article includes a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source. The aerosol-generating system also includes at least one piercing element disposed on one of the aerosol-generating device and the aerosol-generating article, the at least one piercing element being configured to pierce the at least one frangible barrier when activated by a user.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element; an aerosol-generating article, including a medicament source and a volatile delivery enhancing compound source; and at least one resilient member provided in the aerosol-generating device or the aerosol-generating article and being resiliently biased against the heater element, wherein at least one of the medicament source and the volatile delivery enhancing compound source contacts the at least one resilient member, and the aerosol-generating system is configured to heat the medicament source and the volatile delivery enhancing compound source of the aerosol-generating article so that the medicament source has a higher temperature than that of the volatile delivery enhancing compound source.

Abstract: An aerosol-forming article is provided, including an airflow inlet and an airflow outlet; a medicament source and a volatile delivery enhancing compound source disposed between the airflow inlet and the airflow outlet, and a moveable portion moveable between an open position in which the medicament source and the volatile delivery enhancing compound source are in fluid communication with both the airflow inlet and the airflow outlet, and a closed position in which each of the medicament source and the volatile delivery enhancing compound source is in communication with only one or none of the airflow inlet and the airflow outlet.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element; an aerosol-generating article including a medicament source and a volatile delivery enhancing compound source; a bimetallic strip provided in the aerosol-generating device or the aerosol-generating article, the bimetallic strip including a first end in thermal contact with the heater element and a second end in thermal contact with the volatile delivery enhancing compound source, the bimetallic strip being configured so that heating the first end of the bimetallic strip above a predetermined temperature results in displacement of the first end of the bimetallic strip away from the heater element.

Abstract: A method and device are provided for measuring a level of a clinically relevant analyte (such as glucose) in a fluid (such as blood). The device includes a flow path for conducting said fluid through the device; a detection chamber arranged on said flow path; and detector means arranged to detect analyte levels in the fluid in said chamber, wherein: said detection chamber contains a predetermined amount of an analyte such that that analyte mixes with fluid in the detection chamber to form, at the detector means, a calibration sample of the fluid at a time after the arrival of the fluid in said detection chamber, and said detector means is arranged to detect a first analyte level of an unadulterated sample of the fluid at a first time which is before the formation of said calibration sample and to detect a second analyte level of said calibration sample at a second time which is after the formation of said calibration sample.

Abstract: The present invention provides a flexible format for diagnostic tests that is applicable to measuring a wide range of properties of fluids, particularly physiological fluids, by creating a concentration gradient of an indicator in the sample under analysis and measuring a flux of the indicator through the sample which is used to determine a property of the sample. Aspects of the invention include a method of testing a property of a physiological fluid in a portable test device, a portable test device and a kit including a portable test device and a processor.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device, the aerosol-generating article including a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source, the aerosol-generating system further including a rupturing portion forming part of the aerosol-generating device or the aerosol-generating article, the aerosol-generating system being configured to allow relative sliding movement between the rupturing portion and the at least one frangible barrier to rupture the at least one frangible barrier.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element; an aerosol-generating article, including a medicament source and a volatile delivery enhancing compound source; and at least one resilient member provided in the aerosol-generating device or the aerosol-generating article and being resiliently biased against the heater element, wherein at least one of the medicament source and the volatile delivery enhancing compound source contacts the at least one resilient member, and the aerosol-generating system is configured to heat the medicament source and the volatile delivery enhancing compound source of the aerosol-generating article so that the medicament source has a higher temperature than that of the volatile delivery enhancing compound source.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element, and an aerosol-generating article configured to engage with the aerosol-generating device. The aerosol-generating article includes a medicament source, a volatile delivery enhancing compound source, and at least one frangible barrier sealing the medicament source and the volatile delivery enhancing compound source. The aerosol-generating system also includes at least one piercing element disposed on one of the aerosol-generating device and the aerosol-generating article, the at least one piercing element being configured to pierce the at least one frangible barrier when activated by a user.

Abstract: An aerosol-forming article is provided, including an airflow inlet and an airflow outlet; a medicament source and a volatile delivery enhancing compound source disposed between the airflow inlet and the airflow outlet, and a moveable portion moveable between an open position in which the medicament source and the volatile delivery enhancing compound source are in fluid communication with both the airflow inlet and the airflow outlet, and a closed position in which each of the medicament source and the volatile delivery enhancing compound source is in communication with only one or none of the airflow inlet and the airflow outlet.

Abstract: An aerosol-generating system is provided, including an aerosol-generating device including a heater element; an aerosol-generating article including a medicament source and a volatile delivery enhancing compound source; a bimetallic strip provided in the aerosol-generating device or the aerosol-generating article, the bimetallic strip including a first end in thermal contact with the heater element and a second end in thermal contact with the volatile delivery enhancing compound source, the bimetallic strip being configured so that heating the first end of the bimetallic strip above a predetermined temperature results in displacement of the first end of the bimetallic strip away from the heater element.

Abstract: A method and device are provided for measuring a level of a clinically relevant analyte (such as glucose) in a fluid (such as blood). The device includes a flow path for conducting said fluid through the device; a detection chamber arranged on said flow path; and detector means arranged to detect analyte levels in the fluid in said chamber, wherein: said detection chamber contains a predetermined amount of an analyte such that that analyte mixes with fluid in the detection chamber to form, at the detector means, a calibration sample of the fluid at a time after the arrival of the fluid in said detection chamber, and said detector means is arranged to detect a first analyte level of an unadulterated sample of the fluid at a first time which is before the formation of said calibration sample and to detect a second analyte level of said calibration sample at a second time which is after the formation of said calibration sample.

Abstract: The present invention provides a flexible format for diagnostic tests that is applicable to measuring a wide range of properties of fluids, particularly physiological fluids, by creating a concentration gradient of an indicator in the sample under analysis and measuring a flux of the indicator through the sample which is used to determine a property of the sample. Aspects of the invention include a method of testing a property of a physiological fluid in a portable test device, a portable test device and a kit including a portable test device and a processor.

Abstract: A method and device are provided for measuring a level of a clinically relevant analyte (such as glucose) in a fluid (such as blood). The device includes a flow path for conducting said fluid through the device; a detection chamber arranged on said flow path; and detector means arranged to detect analyte levels in the fluid in said chamber, wherein: said detection chamber contains a predetermined amount of an analyte such that that analyte mixes with fluid in the detection chamber to form, at the detector means, a calibration sample of the fluid at a time after the arrival of the fluid in said detection chamber, and said detector means is arranged to detect a first analyte level of an unadulterated sample of the fluid at a first time which is before the formation of said calibration sample and to detect a second analyte level of said calibration sample at a second time which is after the formation of said calibration sample.