Patents by Inventor David F. Gardiner

David F. Gardiner has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinations of Hepatitis C Virus Inhibitors
    Publication number: 20150335655
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit Hepatitis C virus (HCV), compositions comprising such compounds, and methods for treating hepatitis C using such combinations.
    Type: Application
    Filed: July 31, 2015
    Publication date: November 26, 2015
    Inventors: Min Gao, David F. Gardiner, Julie A. Lemm, Fiona McPhee, Stacey A. Voss
  • Codon-optimized DNA molecules encoding the receptor binding domains of toxins A and B, and methods of use thereof
    Patent number: 8852600
    Abstract: In one aspect, the invention provides a DNA molecule. The DNA molecule includes a nucleotide sequence that encodes the receptor-binding domain of Clostridium difficile toxin A or toxin B in which at least about 10% of the in-frame codons for each amino acid residue has a higher percentage use in the human genome than the corresponding in-frame codons of C. difficile toxin A or toxin B having a known sequence. Methods for generating antibodies to Clostridium difficile toxin A or toxin B, methods for reducing the risk of a C. difficile infection, and methods for treating a C. difficile are also provided.
    Type: Grant
    Filed: June 7, 2007
    Date of Patent: October 7, 2014
    Assignees: The Rockefeller University, Cornell University
    Inventors: David F. Gardiner, Yaoxing Huang
  • Combinations of Hepatitis C Virus Inhibitors
    Publication number: 20140235617
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit Hepatitis C virus (HCV), compositions comprising such compounds, and methods for treating hepatitis C using such combinations.
    Type: Application
    Filed: April 28, 2014
    Publication date: August 21, 2014
    Inventors: Min Gao, David F. Gardiner, Julie A. Lemm, Fiona McPhee, Stacey A. Voss
  • Combinations of Hepatitis C Virus Inhibitors
    Publication number: 20120196794
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to combinations of compounds which can inhibit Hepatitis C virus (HCV), compositions comprising such compounds, and methods for treating hepatitis C using such combinations.
    Type: Application
    Filed: August 1, 2011
    Publication date: August 2, 2012
    Inventors: Min Gao, David F. Gardiner, Julie A. Lemm, Fiona McPhee, Stacey A. Voss
  • Codon-Optimized Dna Molecules Encoding the Receptor Binding Domains of Clostridium Difficile Toxins A and B, and Methods of Use Thereof
    Publication number: 20100278868
    Abstract: In one aspect, the invention provides a DNA molecule. The DNA molecule includes a nucleotide sequence that encodes the receptor-binding domain of Clostridium difficile toxin A or toxin B in which at least about 10% of the in-frame codons for each amino acid residue has a higher percentage use in the human genome than the corresponding in-frame codons of C. difficile toxin A or toxin B having a known sequence. Methods for generating antibodies to Clostridium difficile toxin A or toxin B, methods for reducing the risk of a C. difficile infection, and methods for treating a C. difficile are also provided.
    Type: Application
    Filed: June 7, 2007
    Publication date: November 4, 2010
    Inventors: David F. Gardiner, Yaoxing Huang