Patents by Inventor David F. Grant

David F. Grant has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Inhibitors of epoxide hydrolases for the treatment of inflammation
    Patent number: 8815951
    Abstract: The invention provides compounds that inhibit epoxide hydrolase in therapeutic applications for treating hypertension. A preferred class of compounds for practicing the invention have the structure shown by Formula 1 wherein Z is oxygen or sulfur, W is carbon phosphorous or sulfur, X and Y is each independently nitrogen, oxygen, or sulfur, and X can further be carbon, at least one of R1-R4 is hydrogen, R2 is hydrogen when X is nitrogen but is not present when X is sulfur or oxygen, R4 is hydrogen when Y is nitrogen but is not present when Y is sulfur or oxygen, R1 and R3 is each independently C1-C20 substituted or unsubstituted alkyl, cycloalkyl, aryl, acyl, or heterocyclic.
    Type: Grant
    Filed: December 1, 2006
    Date of Patent: August 26, 2014
    Assignee: The Regents of the University of California
    Inventors: Bruce D Hammock, Jiang Zheng, Christophe Morisseau, Kazuhiko Motoba, Mehran F. Moghaddam, Babak Borhan, David F. Grant, Jessica Greene, Marlene F. Sisemore, James Sanborn
  • Material processing system
    Patent number: 7481091
    Abstract: A drive wheel has a generally cylindrical exterior surface with a circumferential groove. A block has a cylindrical working surface in sliding contact with the drive wheel, an operational face with an opening there through. A die is located in the opening and has an interior surface constituting a continuation of the working surface of the block. The die has an exit opening. A diverter is secured to the die and extends into the recess with a leading abutment edge positioned in operative proximity to the exit opening.
    Type: Grant
    Filed: July 27, 2006
    Date of Patent: January 27, 2009
    Inventors: David F. Grant, Patrick B. Berbon, Timothy C. Wang, Paul A. Burkey
  • Epoxide hydrolase inhibitor methods
    Patent number: 6174695
    Abstract: The present invention provides methods of treating inflammatory diseases mediated by poly-unsaturated lipid metabolites by inhibiting epoxide hydrolase, methods for assaying or screening the epoxide hydrolase inhibitors for inhibitory specificity and for toxicity, and novel biologically active tetrahydrofuran diols of arachidonic acid, including antibodies thereto.
    Type: Grant
    Filed: May 14, 1999
    Date of Patent: January 16, 2001
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Mehran F. Moghaddam, Jeffrey M. Cheek, Babak Borhan, James Fergusson, David F. Grant, Jessica F. Greene, Kazuhiko Matoba, Jiang Zheng, Marlene F. Sisemore
  • Dihydroxy-oxy-eicosadienoates
    Patent number: 5955496
    Abstract: The present invention provides novel biologically active tetrahydrofuran diols of arachidonic acid.
    Type: Grant
    Filed: August 12, 1997
    Date of Patent: September 21, 1999
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, Mehran F. Moghaddam, Jeffrey M. Cheek, Babak Borhan, James Fergusson, David F. Grant, Jessica F. Greene, Kazuhiko Matoba, Jiang Zheng, Marlene F. Sisemore
  • Stud and washer system for golf shoe spikes
    Patent number: 5655317
    Abstract: A golf spike system includes a stud having an upper portion in a generally cylindrical configuration with screw threads on its exterior surface, a lower portion having a generally cone shaped configuration, a first intermediate portion adjacent to the upper portion having a surface adapted to mate with a correspondingly shaped surface of a washer, and a second intermediate portion adjacent to the lower portion having a surface adapted to cooperatively couple with an insertion tool and a washer having an aperture therethrough, the aperture having an internal surface adapted to cooperatively receive the first intermediate portion for being rotated thereby during the coupling and uncoupling of the golf spike system with respect to a golf shoe.
    Type: Grant
    Filed: March 4, 1996
    Date of Patent: August 12, 1997
    Inventor: David F. Grant
  • Recombinant soluble epoxide hydrolase
    Patent number: 5445956
    Abstract: The present invention relates to nucleic acid sequences and methods useful for producing recombinant human soluble epoxide hydrolase (sEH).
    Type: Grant
    Filed: August 13, 1993
    Date of Patent: August 29, 1995
    Assignee: The Regents of the University of California
    Inventors: Bruce D. Hammock, David F. Grant, Jeffrey K. Beetham
  • Golf spike
    Patent number: D374762
    Type: Grant
    Filed: August 28, 1995
    Date of Patent: October 22, 1996
    Inventor: David F. Grant