Patents by Inventor David F Horrobin

David F Horrobin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 6630157
    Abstract: Compostions of GLA and/or other EFAs with TA or related compounds, and their use in therapy or nutrition or in preparation of composition for therapy or nutrition, especially to improve cell membrane EFA concentration and/or (particularly in diabetic complications) impaired nerve function and blood flow.
    Type: Grant
    Filed: August 15, 2000
    Date of Patent: October 7, 2003
    Assignee: Viatris GmbH & Co. KG.
    Inventors: David F. Horrobin, Hans-Jurgen Tritschler
  • Publication number: 20030017974
    Abstract: The use in preparation of a medicament for treating and preventing the side effects of anti-cancer chemotherapy of a polyunsaturated fatty acid with a carbon chain length of 14 to 26 and with 2 to 6 double bonds in the molecule in cis or trans configuration, and a method of such treatment or prevention wherein said fatty acid is used as an active.
    Type: Application
    Filed: June 7, 2002
    Publication date: January 23, 2003
    Inventors: Catherine A. Scott, David F. Horrobin
  • Patent number: 6441038
    Abstract: A method of treatment of disorders of neurological origin and drug formulations for use in the method are disclosed. These conditions comprise fatigue and associated syndromes of pain, weakness and depressed mood which are associated with chronic fatigue syndrome, brain injury and stroke, stress, fibromyalgia, and irritable bowel syndrome. The treatment comprises administering to a patient in need thereof a selective inhibitor of noradrenaline reuptake combined with either phenylalanine or tyrosine in the same dosage form or the same pack.# The noradrenergic drug may be selected from lofepramine, desipramine or reboxetine. The selective inhibitor may be a combined inhibitor of both noradrenaline and serotonin reuptake such as venlafaxine, duloxetine or milnacipran, or an inhibitor of both noradrenaline and dopamine reuptake such as bupropion.
    Type: Grant
    Filed: October 12, 2000
    Date of Patent: August 27, 2002
    Assignee: Laxdale Limited
    Inventors: Cari Loder, David F. Horrobin
  • Patent number: 6407075
    Abstract: The use in preparation of a medicament for treating and preventing the side effects of anti-cancer chemotherapy of a polyunsaturated fatty acid with a carbon chain length of 14 to 26 and with 2 to 6 double bonds in the molecule in cis or trans configuration, and a method of such treatment or prevention wherein said fatty acid is used as an active.
    Type: Grant
    Filed: July 6, 1999
    Date of Patent: June 18, 2002
    Inventors: Catherine A. Scott, David F. Horrobin
  • Patent number: 6184251
    Abstract: This invention relates to the administration of arachidonic acid or docosahexaenoic acid or precursors thereof to children or pregnant women for the treatment or prevention of dyspraxia.
    Type: Grant
    Filed: February 4, 2000
    Date of Patent: February 6, 2001
    Assignee: Scotia Holdings PLC
    Inventors: Barbara Jacqueline Stordy, David F. Horrobin
  • Patent number: 6177470
    Abstract: Optimum conditions for prostaglandin synthesis are provided by internally administering an ascorbic-6-acid ester of gamma-linolenic acid or an ascorbic-6-acid ester of dihomo-gamma-linolenic acid.
    Type: Grant
    Filed: March 2, 1998
    Date of Patent: January 23, 2001
    Assignee: Scotia Holdings PLC
    Inventors: David F Horrobin, Philip Knowles, Mehar S Manku
  • Patent number: 5990164
    Abstract: An N-alkylpolyhydroxyamine salt of an n-6 or n-3 essential fatty acid (EFA) that is beyond the 6-desaturation step, or of any polyunsaturated fatty acid, other than those belonging to the n-6 and n-3 series, having 16 to 26 carbon atoms and up to six double bonds, the double bonds being in the cis or trans configuration, the salt being formed with the fatty acid either as such or in the form of a covalent derivative, through the carboxyl group, of a bifunctional compound itself having a free acid function.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: November 23, 1999
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Philip Knowles, Mehar Manku, John C. Stewart
  • Patent number: 5922345
    Abstract: Countering side effects of parenteral or fluid-diet enteral nutrition by adding one or more 6-desaturated essential fatty acids (EFAs) to parenteral or enteral composition (particularly low-fat compositions) being given, or giving them in addition to the compositions.
    Type: Grant
    Filed: January 11, 1996
    Date of Patent: July 13, 1999
    Assignee: Scotia Holdings Plc
    Inventors: David F. Horrobin, Lars Lindmark
  • Patent number: 5888541
    Abstract: Increase gut calcium absorption in humans or animals by the administration of GLA, DGLA or LA as such or in salt or other pharmacologically acceptable form, optionally in association with EPA, DHA or other EFA in similar forms, specifically useful in the treatment of osteoporosis.
    Type: Grant
    Filed: January 15, 1997
    Date of Patent: March 30, 1999
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Brenda E. Reynolds
  • Patent number: 5871757
    Abstract: Polyunsaturated oils such as triply or higher ethylenically unsaturated organic materials are stabilized against ambient temperature atmospheric oxidation by the addition of an essential oil such as thyme oil, oregano oil, pepper oil or clove oil.
    Type: Grant
    Filed: October 16, 1996
    Date of Patent: February 16, 1999
    Assignee: Scotia Holdings PLC
    Inventors: John B. Cloughley, David F Horrobin
  • Patent number: 5866703
    Abstract: Triglycerides with at least two different acids chosen from 6-desaturated essential fatty acids and oleic acid, useful in nutrition and in medicine.
    Type: Grant
    Filed: October 16, 1995
    Date of Patent: February 2, 1999
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Austin McMordie, Mehar Singh Manku, Philip Knowles
  • Patent number: 5859055
    Abstract: Gamma-linolenic acid and/or dihomo-gamma-linolenic acid is used in the preparation of a medicament for inhibiting reocclusion of an artery from which an occlusion or other blockage has been removed, or for preventing occlusion of peripheral or coronary arteries. The medicament may also comprise eicosapentaenoic acid.
    Type: Grant
    Filed: November 14, 1995
    Date of Patent: January 12, 1999
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, John C. M. Stewart
  • Patent number: 5847000
    Abstract: Ascorbyl-GLA or Ascorbyl-DGLA in medicaments for treatment of asthma and other disorders.
    Type: Grant
    Filed: March 28, 1997
    Date of Patent: December 8, 1998
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Philip Knowles, Mehar S Manku
  • Patent number: 5763484
    Abstract: A method of treatment of a disorder, including breast cancer and other cancer, with effective amounts of one or more of the metabolites of linoleic acid (GLA, DGLA, AA, 22:4n-y or 22:5n-6) and one or more of the metabolites of .alpha.-linolenic acid (18:4n-3, 20:4n-3, 20:5n-3, 22:5n-3 or 22:6n-3) administered as such or in the form of an ester, salt, amide or other derivative convertible in the body thereto alone or in acceptable pharmaceutical carrier or diluent.
    Type: Grant
    Filed: March 24, 1997
    Date of Patent: June 9, 1998
    Assignee: Scotia Holdings plc
    Inventor: David F. Horrobin
  • Patent number: 5670540
    Abstract: A triglyceride for use in therapy or as a nutritional supplement, or a composition containing a triglyceride, wherein the triglyceride comprises a fatty acid selected from gamma-linolenic acid and the n-6 EPAs naturally derived therefrom and stearidonic acid and the n-3 EFAs naturally derived therefrom, forming a triple ester with glycerol or alternatively forming a double ester in which the other esterifying acide is a single residue of linoleic acid, with the proviso that the di-gammalinolenoyl-mono-linoleoyl glyceride if selected is used as a preparation containing more than 20% by weight thereof.
    Type: Grant
    Filed: May 15, 1995
    Date of Patent: September 23, 1997
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Philip Knowles, Mehar Singh Manku, Austin McMordie
  • Patent number: 5663202
    Abstract: Damage to the gastrointestinal tract as a consequence of exposure to ionising radiation is prevented or treated by administration of GLA and/or DGLA. Medicaments containing GLA and/or DGLA for such treatment or prevention may also further comprise EPA and/or DHA.
    Type: Grant
    Filed: July 31, 1996
    Date of Patent: September 2, 1997
    Assignee: Soctia Holdings PLC
    Inventors: David F. Horrobin, Catherine A. Scott
  • Patent number: 5635189
    Abstract: A natural vitamin E preparation, i.e. vitamin E extracted from natural sources, comprising one or more of the alpha-, beta-, gamma- and delta-tocopherol forms, either as the tocopherol itself, or as a derivative, such as the acetate, in which the total concentration of Wendt PAHs is less than 100 ppb.
    Type: Grant
    Filed: August 29, 1994
    Date of Patent: June 3, 1997
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Mehar S. Manku
  • Patent number: 5620701
    Abstract: Atopic eczema, breast pain or premenstrual syndrome are treated by administering to a person in need of same a composition containing at least 20% di-linoleoyl-mono-gamma-linolenyl glycerol by weight.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: April 15, 1997
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Yung-Sheng Huang
  • Patent number: 5618558
    Abstract: Increasing gut calcium absorption in humans or animals by the administration of GLA, DGLA or LA as such or in salt or other pharmacologically acceptabe form, optionally in association with EPA, DHA or other EFA in similar forms, specifically useful in treatment of osteoporosis.
    Type: Grant
    Filed: August 16, 1993
    Date of Patent: April 8, 1997
    Assignee: Scotia Holdings PLC
    Inventors: David F. Horrobin, Brenda E. Reynolds
  • Patent number: 5614208
    Abstract: Atopic eczema, breast pain or premenstrual syndrome are treated by administering to a person in need of same a composition containing at least 20% di-linoleoyl-mono-gamma-linolenyl glycerol by weight.
    Type: Grant
    Filed: February 14, 1996
    Date of Patent: March 25, 1997
    Assignee: Efamol Holdings PLC
    Inventors: David F. Horrobin, Yung-Sheng Huang