Patents by Inventor David F. Woodward

David F. Woodward has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE
    Publication number: 20140249192
    Abstract: The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfonamido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Application
    Filed: February 12, 2014
    Publication date: September 4, 2014
    Applicant: Allergan, Inc.
    Inventors: Jose L. Martos, William R. Carling, David F. Woodward, Jenny W. Wang, Jussi J. Kangasmetsa
  • FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN
    Publication number: 20140187596
    Abstract: The present invention provides a method of treating a patient suffering from pain or other FAAH mediated conditions by administering a fatty acid amide inhibiting amount of a compound represented by the formula: wherein R1 is H; R2 is a radical selected from the group consisting of H, hydrocarbyl and substituted hydrocarbyl; R3 is a radical selected from the group consisting of H, hydrocarbyl and substituted hydrocarbyl; X is CHCH, (CH2)n or O(CH2)n, wherein n is 0 or an integer of from 1 to 4; and W is O, S, or NR6, wherein R6 is selected from the group consisting of H and alkyl.
    Type: Application
    Filed: May 23, 2012
    Publication date: July 3, 2014
    Applicant: ALLERGAN, INC.
    Inventors: David F. Woodward, Jose L. Martos, William R. Carling, Andrew D. Jones, Jenny W. Wang
  • COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE
    Publication number: 20140121258
    Abstract: The present invention provides a compound, that is a 1-[(2-{[(alkyl or aryl)methyl]oxyl}halo or haloalkyl substituted-phenyl)alkyl]-5-hydrocarbyl or substituted hydrocarbyl-1H-pyrazole carboxylic acid or alkylenylcarboxylic acid or a hydrocarbyl or substituted hydrocarbyl sulfonamide of said carboxylic acid or said alkylenylcarboxylic acid, provided however said compound is not a 3-carboxylic acid, a sulfonamide thereof, or a 3-methylenylcarboxylic acid. The compound may be represented by the following formula (I). Wherein R1, R2, R3, R4, R5, R6, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Application
    Filed: July 1, 2011
    Publication date: May 1, 2014
    Applicant: ALLERGAN, INC.
    Inventors: David F. Woodward, William R. Carling, Jose L. Martos, Jenny W. Wang, Jussi J. Kangasmetsa
  • NOVEL PROSTAMIDES FOR THE TREATMENT OF GLAUCOMA AND RELATED DISEASES
    Publication number: 20140107124
    Abstract: Disclosed herein are compositions comprising an amide related to a prostaglandin and a biogenic amine. Other aspects relate to certain chemical compounds, pharmaceutical compositions, and methods of treating glaucoma.
    Type: Application
    Filed: December 20, 2013
    Publication date: April 17, 2014
    Applicant: Allergan, Inc.
    Inventors: David F. Woodward, Robert M. Burk
  • Hypotensive Lipid And Timolol Compositions And Methods Of Using Same
    Publication number: 20140051704
    Abstract: New compositions for and methods of treating ocular hypertension provide for effective treatment of ocular hypertension often using reduced concentrations of active components. Such compositions include a timolol component and a hypotensive lipid component.
    Type: Application
    Filed: October 24, 2013
    Publication date: February 20, 2014
    Applicant: ALLERGAN, INC.
    Inventors: June Chen, David F. Woodward, Alexander B. Kharlamb
  • Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
    Patent number: 8653118
    Abstract: The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfon-amido)propyl)benzyl)pyrrolidin-2-yl)oxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Grant
    Filed: August 19, 2011
    Date of Patent: February 18, 2014
    Assignee: Allergan, Inc.
    Inventors: Jose L. Martos, William R. Carling, David F. Woodward, Jenny W. Wang, Jussi J Kangasmetsa
  • Prostamides for the treatment of glaucoma and related diseases
    Patent number: 8648213
    Abstract: Disclosed herein are compositions comprising an amide related to a prostaglandin and a biogenic amine. Other aspects relate to certain chemical compounds, pharmaceutical compositions, and methods of treating glaucoma.
    Type: Grant
    Filed: October 4, 2005
    Date of Patent: February 11, 2014
    Assignee: Allergan, Inc.
    Inventors: David F. Woodward, Robert M. Burk
  • Method of enhancing hair growth
    Patent number: 8632760
    Abstract: Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
    Type: Grant
    Filed: April 6, 2012
    Date of Patent: January 21, 2014
    Assignee: Allergan, Inc.
    Inventors: David F. Woodward, Amanda M. VanDenburgh
  • Hypotensive lipid and timolol compositions and methods of using same
    Patent number: 8629140
    Abstract: New compositions for and methods of treating ocular hypertension provide for effective treatment of ocular hypertension often using reduced concentrations of active components. Such compositions include a timolol component and a hypotensive lipid component. The present compositions and methods are relatively straightforward, can be easily produced, for example, using conventional manufacturing techniques, and can be easily and conveniently practiced, for example, using application or administration techniques or methodologies which are substantially similar to those employed with prior compositions used to treat ocular hypertension.
    Type: Grant
    Filed: May 22, 2002
    Date of Patent: January 14, 2014
    Assignee: Allergan, Inc.
    Inventors: June Chen, David F. Woodward, Alexander B. Kharlamb
  • Hypotensive lipid and timolol compositions and methods of using same
    Patent number: 8618093
    Abstract: New compositions for and methods of treating ocular hypertension provide for effective treatment of ocular hypertension often using reduced concentrations of active components. Such compositions include a timolol component and a hypotensive lipid component. The present compositions and methods are relatively straightforward, can be easily produced, for example, using conventional manufacturing techniques, and can be easily and conveniently practiced, for example, using application or administration techniques or methodologies which are substantially similar to those employed with prior compositions used to treat ocular hypertension.
    Type: Grant
    Filed: March 20, 2009
    Date of Patent: December 31, 2013
    Assignee: Allergan, Inc.
    Inventors: June Chen, David F. Woodward, Alexander B. Kharlamb
  • Ester Derivatives of Bimatoprost Compositions and Methods
    Publication number: 20130324606
    Abstract: Provided herein, inter alia, are prodrugs of bimatoprost, methods of using the same and compositions including the same.
    Type: Application
    Filed: February 13, 2012
    Publication date: December 5, 2013
    Applicant: ALLERGAN, INC.
    Inventors: David F. Woodward, Jenny W. Wang, Neil J. Poloso, Todd S. Gac, Robert M. Burk, Michael E. Garst
  • METHOD OF ENHANCING HAIR GROWTH
    Publication number: 20130296435
    Abstract: Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include a cyclopentane heptanoic acid, 2-cycloalkyl or arylalkyl compound represented by the formula I wherein the dashed bonds represent a single or double bond which can be in the cis or trans configuration, A, B, Z, X, R1 and R2 are as defined in the specification. Such compositions are used in treating the skin or scalp of a human or non-human animal. Bimatoprost is preferred for this treatment.
    Type: Application
    Filed: July 9, 2013
    Publication date: November 7, 2013
    Inventors: David F. Woodward, Amanda M. VanDenburgh
  • COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE
    Publication number: 20130253028
    Abstract: The present invention provides a compound, that is a 1-[(2-{[(alkyl or aryl)methyl]oxy}halo or haloalkyl substituted-phenyl)alkyl]-5-hydrocarbyl or substituted hydrocarbyl-1H-pyrazole carboxylic acid or alkylenylcarboxylic acid or a hydrocarbyl or substituted hydrocarbyl sulfonamide of said carboxylic acid or said alkylenylcarboxylic acid, provided however said compound is not a 3-carboxylic acid, a sulfonamide thereof, or a 3-methylenylcarboxylic acid. The compound may be represented by the following formula Wherein R1, R2, R3, R4, R5, R6, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Application
    Filed: May 20, 2013
    Publication date: September 26, 2013
    Applicant: ALLERGAN, INC.
    Inventors: WILLIAM R. CARLING, JOSE L. MARTOS, DAVID F. WOODWARD, JENNY W. WANG, JUSSI J. KANGASMETSA
  • Compounds act at multiple prostaglandin receptors giving a general anti-inflammatory response
    Patent number: 8492424
    Abstract: The present invention provides a compound, that is a 1-[(2-{[(alkyl or aryl)methyl]oxy}halo or haloalkyl substituted-phenyl)alkyl]-5-hydrocarbyl or substituted hydrocarbyl-1H-pyrazole carboxylic acid or alkylenylcarboxylic acid or a hydrocarbyl or substituted hydrocarbyl sulfonamide of said carboxylic acid or said alkylenylcarboxylic acid, provided however said compound is not a 3-carboxylic acid, a sulfonamide thereof, or a 3-methylenylcarboxylic acid. The compound may be represented by the following formula Wherein R1, R2, R3, R4, R5, R6, X, W, X and Y are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Grant
    Filed: June 28, 2011
    Date of Patent: July 23, 2013
    Assignee: Allergan, Inc.
    Inventors: William R. Carling, Jose L. Martos, David F. Woodward, Jenny W. Wang, Jussi J. Kangasmetsa
  • COMPOUNDS ACT AT MULTIPLE PROSTAGLANDIN RECEPTORS GIVING A GENERAL ANTI-INFLAMMATORY RESPONSE
    Publication number: 20130150417
    Abstract: The present invention provides compounds, that are N-alkyl-2-(1-(5-substituted-2-(3-oxo-3-(trifluoromethylsulfon-amido)propyl)benzyppyrrolidin-2-ypoxazole-4-carboxamide wherein the 5 substituent is selected from the group consisting of halo and alkyloxy radicals. The compound may be represented by the following formula wherein R1 is selected from the group consisting of CO2R7 and CON(R7)SO2R7 wherein R1, R2, R3, R4, and R7 are as defined in the specification. The compounds may be administered to treat DP1, FP, EP1, EP3, TP and/or EP4 receptor mediated diseases or conditions.
    Type: Application
    Filed: August 19, 2011
    Publication date: June 13, 2013
    Applicant: ALLERGAN, INC.
    Inventors: Jose L. Martos, William R. Carling, David F. Woodward, Jenny W. Wang, Jussi J. Kangasmetsa
  • S1P ANTAGONISTS AS ADJUNCT OCULAR HYPOTENSIVES
    Publication number: 20130079290
    Abstract: The invention provides compositions and methods for further reducing IOP in a subject who has already achieved maximal IOP reduction using known IOP lowering agents. The activity of an ocular hypotensive treatment regimen may be increased by adding an S1P antagonist to prevent S1P mediated reversal as a result of decreased aqueous humor outflow.
    Type: Application
    Filed: March 26, 2012
    Publication date: March 28, 2013
    Applicant: ALLERGAN, INC.
    Inventors: David F. Woodward, Todd M. Heidelbaugh, W. Daniel Stamer
  • COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS, HAIR THINNING, AND HAIR COLOR LOSS
    Publication number: 20130041025
    Abstract: Described herein are compositions including prostaglandin analogs including prostamides and methods for using these compositions for increasing eyelash and eyebrow growth and hair growth on the scalp.
    Type: Application
    Filed: March 23, 2011
    Publication date: February 14, 2013
    Applicant: ALLERGAN, INC.
    Inventors: John G. Walt, David F. Woodward, Amanda M. Vandenburgh
  • COMPOSITIONS AND METHODS FOR TREATING HAIR LOSS, HAIR THINNING, AND HAIR COLOR LOSS
    Publication number: 20130030055
    Abstract: Described herein are compositions including at least one prostaglandin or prostamide and methods for using these compositions for increasing hair growth on the scalp eyebrow growth.
    Type: Application
    Filed: March 23, 2011
    Publication date: January 31, 2013
    Applicant: ALLERGAN, INC.
    Inventors: John G. Walt, David F. Woodward, Amanda M. Vandenburgh
  • FATTY ACID AMIDE HYDROLASE INHIHIBITORS FOR TREATING PAIN
    Publication number: 20120329843
    Abstract: The present invention provides a method of treating a patient suffering from pain or other FAAH mediated conditions by administering a fatty acid amide inhibiting amount of a compound represented by the formula: wherein R1 is H; R2 is a radical selected from the group consisting of H, hydrocarbyl and substituted hydrocarbyl; R3 is a radical selected from the group consisting of H, hydrocarbyl and substituted hydrocarbyl; X is CHCH, (CH2)n or O(CH2)n, wherein n is 0 or an integer of from 1 to 4; and W is O, S, or NR6, wherein R6 is selected from the group consisting of H and alkyl.
    Type: Application
    Filed: May 23, 2012
    Publication date: December 27, 2012
    Inventors: David F. Woodward, Jose L. Martos, William R. Carling, Andrew D. Jones, Jenny W. Wang
  • METHOD OF ENHANCING HAIR GROWTH
    Publication number: 20120302588
    Abstract: Methods and compositions for stimulating the growth of hair are disclosed wherein said compositions include bimatoprost and minoxidil in a vehicle for topical application to the skin of a mammal, e.g. a human, whereby the combination of bimatoprost and minoxidil produces a faster onset of hair growth in humans or other mammals and wherein said composition brings about a synergestic result of faster onset of hair growth as compared to compositions comprising bimatoprost and minoxidil, alone.
    Type: Application
    Filed: January 30, 2012
    Publication date: November 29, 2012
    Inventors: David F. Woodward, Jenny W. Wang