Patents by Inventor David Fairfax

David Fairfax has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Pyrazole derivatives as ERK inhibitors
    Patent number: 8697697
    Abstract: This invention describes substituted pyrazole derivatives of Formula I and methods of making and using the compounds. These compounds have utility in the treatment of conditions or diseases in which modification of the activity of ERK would have a positive therapeutic outcome, for instance various cancers, psoriasis and actinic keratosis.
    Type: Grant
    Filed: January 3, 2012
    Date of Patent: April 15, 2014
    Assignee: Kinentia Biosciences LLC
    Inventors: David Fairfax, Russell Joseph Deorazio
  • PYRAZOLE DERIVATIVES AS ERK INHIBITORS
    Publication number: 20140011806
    Abstract: This invention describes substituted pyrazole derivatives of Formula I and methods of making and using the compounds. These compounds have utility in the treatment of conditions or diseases in which modification of the activity of ERK would have a positive therapeutic outcome, for instance various cancers, psoriasis and actinic keratosis.
    Type: Application
    Filed: January 3, 2012
    Publication date: January 9, 2014
    Applicant: KINENTIA BIOSCIENCES LLC
    Inventors: David Fairfax, Russell Joseph Deorazio
  • COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES
    Publication number: 20120083495
    Abstract: Compounds useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Application
    Filed: December 5, 2011
    Publication date: April 5, 2012
    Applicants: SCIENCE APPLICATIONS INTERNATIONAL INC. (SAIC), ALBANY MOLECULAR RESEARCH, INC., DEPARTMENT OF HEALTH AND HUMAN SERVICES
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • Compounds for the treatment of spinal muscular atrophy and other uses
    Patent number: 8110681
    Abstract: Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Grant
    Filed: March 13, 2007
    Date of Patent: February 7, 2012
    Assignees: The United States of America as represented by the Secretary, Department of Health and Human Services, Albany Molecular Research, Inc., Science Applications International Inc. (SAIC)
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • COMPOUNDS FOR THE TREATMENT OF SPINAL MUSCULAR ATROPHY AND OTHER USES
    Publication number: 20090312323
    Abstract: Compounds of Formula (I) or (II) useful for the treatment of spinal muscular atrophy or other uses, as well as methods of using such compounds to increase SMN expression, increase EAAT2 expression, or increase the expression of a nucleic acid that encodes a translational stop codon introduced by mutation or frameshift.
    Type: Application
    Filed: March 16, 2007
    Publication date: December 17, 2009
    Applicants: The Government of the United States of America, as represented by the Secretary, Department of HHS, Albany Molecular Research, Inc., Science Applications International Corporation
    Inventors: Jill Heemskerk, Keith D. Barnes, John M. McCall, Graham Johnson, David Fairfax, Matthew Robert Johnson
  • Benzoxazole Carboxamides For Treating CINV and IBS-D
    Publication number: 20080108609
    Abstract: Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.
    Type: Application
    Filed: November 2, 2007
    Publication date: May 8, 2008
    Applicant: AMR TECHNOLOGY, INC.
    Inventors: David Fairfax, Zhicai Yang
  • Novel soluble 1,4 benzodiazepine compounds and stable salts thereof
    Publication number: 20080064686
    Abstract: The present invention relates to novel chemical compounds, methods for their discovery, and their therapeutic use. In particular, the present invention provides benzodiazepine derivatives and related compounds and methods of using benzodiazepine derivatives and related compounds as therapeutic agents to treat a number of conditions associated with the faulty regulation of the processes of programmed cell death, autoimmunity, inflammation, hyperproliferation, and the like.
    Type: Application
    Filed: April 26, 2007
    Publication date: March 13, 2008
    Applicant: The Regents of the University of Michigan
    Inventors: Manzer Durrani, William Geiss, David Fairfax, Dmytro Tymoshenko, Van-Duc Le, Lisa Peterson
  • Tricycloundecane compounds useful as modulators of nuclear hormone receptor function
    Publication number: 20070088029
    Abstract: Tricycloundecanes compounds, methods of using such compounds in the treatment of nuclear hormone receptor-associated conditions such as cancer and immune disorders, and pharmaceutical compositions containing such compounds are disclosed.
    Type: Application
    Filed: October 17, 2006
    Publication date: April 19, 2007
    Inventors: James Balog, David Fairfax, Gregory Martin, Mark Salvati, Hai-Yun Xiao
  • Benzoxazole carboxamides for treating CINV and IBS-D
    Publication number: 20060183769
    Abstract: Compounds of formulae I and II: are disclosed as 5-HT3 inhibitors. Those compounds that exhibit central activity are useful in treating CINV; those that inhibit peripheral receptors are useful to treat IBS-D.
    Type: Application
    Filed: February 17, 2006
    Publication date: August 17, 2006
    Applicant: AMR Technology, Inc.
    Inventors: David Fairfax, Zhicai Yang